Fasting impairs type 2 helper T cell infiltration in the lung of an eosinophilic asthma mouse model
Eosinophilic asthma is a form of bronchial asthma that is caused by the pulmonary infiltration of eosinophils and accounts for approximately half of the patients with severe asthma.
Yusuke Suzuki+7 more
doaj +1 more source
Reduction of Rescue Treatment With Dupilumab for Chronic Rhinosinusitis With Nasal Polyps in Japan
This observational study examined the impact of add‐on dupilumab treatment on the use of rescue therapy in Japanese individuals with chronic rhinosinusitis with nasal polyps (CRSwNPs) using data from a large hospital‐based administrative claims database.
Mamoru Yoshikawa+5 more
wiley +1 more source
Source-specific contributions of particulate matter to asthma-related pediatric emergency department utilization [PDF]
Few studies have linked specific sources of ambient particulate matter smaller than 2.5 $\mu$m (PM2.5) and asthma. In this study, we estimated the contributions of specific sources to PM2.5 and examined their association with daily asthma hospital utilization in Cincinnati, Ohio, USA.
arxiv +1 more source
Recovery of smell sense loss by mepolizumab in a patient allergic to dermatophagoides and affected by chronic rhinosinusitis with nasal polyps [PDF]
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) frequently presents with dysfunction or loss of the sense of smell, resulting in a signifcant impairment in quality of life.
Cavaliere, Carlo+7 more
core +1 more source
Cannabinoids and the Endocannabinoid System in the Treatment of Chronic Rhinosinusitis
The objective of this scoping review is to explore the role of the ECS in the pathophysiology of CRS. We identified five studies, all supporting a common conclusion that the ECS is implicated in regulating cellular inflammatory pathways potentially involved in sinonasal disease.
John J. W. Lee+7 more
wiley +1 more source
Sinonasal Intervention Reduces the Need for Pressure Equalization Tube Placement in Atopic Adults
Surgical and medical management of atopic sinonasal diseases decreases the risk of middle ear disease and the subsequent need for pressure equalization tubes. ABSTRACT Objectives To determine the impact of management of upper airway atopic disease on middle ear and eustachian tube function in adults.
Lawrance Lee+3 more
wiley +1 more source
Severe Asthma—Perspectives From Adult and Pediatric Pulmonology
Both adults and children with severe asthma represent a small proportion of the asthma population; however, they consume disproportionate resources. For both groups it is important to confirm the diagnosis of severe asthma and ensure that modifiable ...
Louise Fleming, Liam Heaney
doaj +1 more source
Bariatric Surgery Lowers Incidence of Chronic Rhinosinusitis and Functional Endoscopic Sinus Surgery
Obesity is associated with an increased risk of chronic rhinosinusitis (CRS) and increased recurrence of CRS after functional endoscopic sinus surgery (FESS). This study found that in patients with obesity, undergoing bariatric surgery decreases the risk of new‐encounter diagnoses of CRS and results in fewer FESS.
Shvetali Thatte, Mohamad R. Chaaban
wiley +1 more source
Twelve-year follow-up study after endoscopic sinus surgery in patients with chronic rhinosinusitis with nasal polyposis [PDF]
Background Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a therapeutic challenge because of the high recurrence rate. Surgical intervention should be considered in patients who fail to improve after medical treatment.
Bachert, Claus+7 more
core +1 more source
Factors Affecting Nasal Discharge in Chronic Rhinosinusitis Patients
This study aimed to identify patient‐specific factors influencing the severity of nasal drainage in chronic rhinosinusitis (CRS) patients. It found that postnasal discharge (PND) was the most severe symptom, with female gender, CRS without nasal polyps, prior endoscopic sinus surgery, and allergies significantly associated with severe PND.
Pranav A. Patel+7 more
wiley +1 more source