Expert Perspectives on a Clinical Challenge: Hematologic Malignancies and Vasculitis
Systemic vasculitis describes a collection of rare diseases each caused by inflammation of blood vessel walls that can cause severe systemic complications [[3, 4]](#ref‐0003). The pattern of vascular inflammation and resultant damage is frequently variable and may be mimicked, or directly triggered, by infection or malignancy.
Michelle L. Robinette, Hetty E. Carraway
wiley +1 more source
Leukemoid Reaction in Complicated Haemorrhagic Fever with Renal Syndrome [PDF]
Hantaan Virus (HTNV) infections are mostly associated with fever, haemorrhagic and renal manifestations, known as Haemorrhagic Fever with Renal Syndrome (HFRS). We herein describe three cases with acute HTNV infection, confirming that HTNV infection may
Xiaopeng Yang+4 more
doaj +1 more source
Adverse effects of vaccinations against the Corona-virus SARS-CoV-2: insights and hindsights from a statistical perspective [PDF]
Vaccinations against the virus SARS-CoV-2 have proven to be most effective against a severe corona disease. However, a significant minority of people is still critical of such a vaccination or even strictly reject it. One but surely not the only reason for this is the fear of undesired adverse effects.
arxiv
The cap-snatching SFTSV endonuclease domain is an antiviral target [PDF]
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus with 12%-30% case mortality rates and is related to the Heartland virus (HRTV) identified in the United States.
Amarasinghe, Gaya K+11 more
core +1 more source
Epidemiologic Features and Environmental Risk Factors of Severe Fever with Thrombocytopenia Syndrome, Xinyang, China [PDF]
Background:Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease discovered in rural areas of Central China in 2009, caused by a novel bunyavirus ...
Cao, W.-C. (Wu-Chun)+16 more
core +4 more sources
Engineering strategies to mitigate toxicities associated with CAR‐T cell therapy
This review provides a brief overview of several of the major, and potentially life‐threatening, toxicities associated with CAR T cell therapies and discusses various examples of the genetic and chemical engineering strategies employed to effectively mitigate such toxicities in preclinical models and clinical studies. Abstract Chimeric antigen receptor
Tyler Wolter, Yixin Wang, Quanyin Hu
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FIGO guideline on liver disease and pregnancy
Abstract The number of women entering pregnancy with chronic liver disease is rising. Gestational liver disorders affect 3% of the pregnant population. Both can be associated with significant maternal and fetal morbidity and mortality. European guidance has recently been published to inform management.
Melanie Nana+24 more
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Human Antibody Neutralizes Severe Fever with Thrombocytopenia Syndrome Virus, an Emerging Hemorrhagic Fever Virus [PDF]
ABSTRACT Severe fever with thrombocytopenia syndrome virus (SFTSV), a newly discovered member of the Bunyaviridae family, is the causative agent of an emerging hemorrhagic fever, SFTS, in China. Currently, there are no vaccines or effective therapies against SFTS.
Jianli Hu+18 more
openaire +2 more sources
Ticks on the run: A mathematical model of Crimean-Congo Haemorrhagic Fever (CCHF)-key factors for transmission [PDF]
Crimean-Congo haemorrhagic fever (CCHF) is a tick-borne zoonotic disease caused by the Crimean-Congo hemorrhagic fever virus (CCHFV). Ticks belonging to the genus \textit{Hyalomma} are the main vectors and reservoir for the virus. It is maintained in nature in an endemic vertebrate-tick-vertebrate cycle.
arxiv
Abstract Purpose Platelet‐rich plasma (PRP) could be a vector for certain diseases, and its composition may vary by pathologic condition. The main comorbidities that could affect PRP composition are infectious, oncologic and haematologic. In addition to potential alteration of clinical response, these pathologies could have a significant impact on the ...
Florent Eymard+33 more
wiley +1 more source