Results 141 to 150 of about 3,150,561 (392)
Cytometry Part A, EarlyView.ABSTRACT This 36‐color flow cytometry panel is designed to characterize multiple lymphocyte compartments, with a focus on T cells, their memory subpopulations, and immune checkpoints in human whole blood samples. In clinical settings, the amount of blood available from patients for scientific research is often limited.
Marie‐Theres Thieme‐Ehlert +3 more
wiley +1 more source
The management and treatment of malaria [PDF]
, 1989 Falciparum malaria can create severe complications. Antimalarial drugs such as quinine or chloroquine help in the treatment and management to these complications. The use of chemoprophylaxis is a must for persons travelling abroad to countries subject to
Gilles, Herbert M.
core
Environmental and Molecular Mutagenesis, EarlyView.Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons +17 more
wiley +1 more source
Oxidative Medicine and Cellular Longevity, 2015 Oxidative stress plays an important role in the pathogenesis of falciparum malaria, a disease still claiming close to 1 million deaths and 200 million new cases per year.
E. Schwarzer +2 more
semanticscholar +1 more source
The upside of epilepsy: Theories of an evolutionary paradox
Epilepsia Open, EarlyView.Abstract The persistence of common, heritable conditions, like epilepsy, that are associated with reduced reproductive fitness is an evolutionary paradox. Endogenous analgesic, anti‐depressant, and inflammatory mechanisms able to repair compromised functions can offer advantages in unexpected crises.
Alyssa Ailion +3 more
wiley +1 more source
Cytoadherence in paediatric malaria: ABO blood group, CD36, and ICAM1 expression and severe Plasmodium falciparum infection [PDF]
, 2012 As a leading cause of childhood mortality worldwide, selection pressure by Plasmodium falciparum continues to shape the human genome. Severe disturbances within the microcirculation result from the adhesion of infected erythrocytes to host receptors on ...
Cserti-Gazdewich, Christine M +8 more
core +2 more sources
Exploring the Potential and Advancements of Circular RNA Therapeutics
Exploration, EarlyView.Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang +6 more
wiley +1 more source
Impact of Malaria Severity on Serum Levels of Hepcidin and Iron Status in Children
Online Journal of Health & Allied Sciences, 2019 Malaria is a life threatening disease and one of the leading causes of death in Africa especially in children. This study aimed to assess the impact of malaria on levels of hepcidin and iron status (haemoglobin, serum iron and total iron binding capacity)
Oluboyo, O. Adeola +3 more
doaj
Clinical and epidemiological characterization of severe Plasmodium vivax malaria in Gujarat, India
Virulence, 2020 The mounting evidence supporting the capacity of Plasmodium vivax to cause severe disease has prompted the need for a better characterization of the resulting clinical complications. India is making progress with reducing malaria, but epidemics of severe
Anupkumar R. Anvikar +11 more
doaj +1 more source
In vitro inhibition of Plasmodium falciparum rosette formation by Curdlan sulfate [PDF]
, 2007 Spontaneous binding of infected erythrocytes to uninfected erythrocytes to form rosettes is a property of some strains of Plasmodium falciparum that is linked to severe complications of malaria.
Arman, Monica +7 more
core +2 more sources