Results 1 to 10 of about 56,821 (298)
Frontiers in Medicine, 2022 Multiple sevoflurane exposure may result in cognitive deficits in neonatal animals. This study attempted to investigate the potential mechanism of sevoflurane-induced neurotoxicity in developing hippocampus.
Piao Zhang +3 more
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Effect of histone demethylase KDM5B on long-term cognitive impairment in neonatal rats induced by sevoflurane [PDF]
Frontiers in Molecular NeuroscienceIntroductionWhether repeated inhalation of sevoflurane during the neonatal period causes long-term learning and memory impairments in humans is unclear.
Yanhong Wang +8 more
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Sevoflurane Preconditioning Increases Stress Resistance via IMB-2/DAF-16 in Caenorhabditis Elegans
Dose-Response, 2022 Sevoflurane preconditioning has been proved to possess therapeutic effects on stress. However, the mechanism by which sevoflurane preconditioning protects against stress remains unclear.
Yue Cao MMed +5 more
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Chinese Journal of Physiology, 2023 Anesthetics exposure induces neurocognitive deficits during brain development and impairs self-renewal and differentiation of neural stem cells (NSCs).
Minmin Cai, Xiang Gao, Shenghui Yu
doaj +1 more source
F1000Research, 2015 Sevoflurane has been available for clinical practice for about 20 years. Nowadays, its pharmacodynamic and pharmacokinetic properties together with its absence of major adverse side effects on the different organ systems have made this drug accepted worldwide as a safe and reliable anesthetic agent for clinical practice in various settings.
Stefan De Hert, Anneliese Moerman
openaire +3 more sources
NUDT21 relieves sevoflurane-induced neurological damage in rats by down-regulating LIMK2
Open Life Sciences, 2023 Postoperative cognitive dysfunction (POCD) is a common complication of cognitive decline after surgery and anesthesia. Sevoflurane, as a commonly used anesthetic, was found to cause POCD. Nudix Hydrolase 21 (NUDT21), a conserved splicing factor, has been
Zhong Yuanping +5 more
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Frontiers in Aging Neuroscience, 2022 Sevoflurane anesthesia induces cognitive impairment, which may lead to perioperative neurocognitive disorders (PND). However, the factors and molecular mechanism underlying this impairment remains unclear.
Lichi Xu +13 more
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Direct and specific effect of sevoflurane anesthesia on rat Per2 expression in the suprachiasmatic nucleus. [PDF]
PLoS ONE, 2013 BACKGROUND: Our previous studies revealed that application of the inhalation anesthetic, sevoflurane, reversibly repressed the expression of Per2 in the mouse suprachiasmatic nucleus (SCN). We aimed to examine whether sevoflurane directly affects the SCN.
Megumi Anzai +10 more
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Influence of the sevoflurane concentration on the occurrence of epileptiform EEG patterns. [PDF]
PLoS ONE, 2014 OBJECTIVES AND AIM: This study was performed to analyse the effects of different sevoflurane concentrations on the incidence of epileptiform EEG activity during induction of anaesthesia in children in the clinical routine. BACKGROUND: It was suggested in
Ines Kreuzer +3 more
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