Sevoflurane posttreatment prevents oxidative and inflammatory injury in ventilator-induced lung injury. [PDF]
PLoS ONE, 2018 Mechanical ventilation is a life-saving clinical treatment but it can induce or aggravate lung injury. New therapeutic strategies, aimed at reducing the negative effects of mechanical ventilation such as excessive production of reactive oxygen species ...
Julie Wagner +7 more
doaj +1 more source
Mediators of Inflammation, 2020 To investigate the mechanism dexmedetomidine in relieving the neurotoxicity of a developing brain induced by sevoflurane. Sprague-Dawley rats, 6 days old, were randomly divided into three groups.
Yunxia Dong +5 more
doaj +1 more source
miRNA‐384‐3p alleviates sevoflurane‐induced nerve injury by inhibiting Aak1 kinase in neonatal rats
Brain and Behavior, 2022 Objective Sevoflurane is a common anesthetic and is widely used in pediatric clinical surgery to induce and maintain anesthesia through inhalation. Increasing studies have revealed that sevoflurane has neurotoxic effects on neurons, apoptosis, and memory
Yuanyuan Chen, Xuan Gao, Hao Pei
doaj +1 more source
The effects of rapid increases in desflurane and sevoflurane concentrations on spirometry in humans during balanced anesthesia with remifentanil [PDF]
, 2008 Background: The noble gas helium induces pre- and postconditioning in animals and humans. Volatile anesthetics induce cardioprotection in humans undergoing coronary artery bypass graft (CABG) surgery.
De Baerdemaeker, Luc +3 more
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Mechanisms of the beneficial effect of sevoflurane in liver ischemia/reperfusion injury [PDF]
Acta Cirúrgica Brasileira, 2015 PURPOSE: To evaluate the underlying mechanisms by which sevoflurane protects the liver against ischemia/reperfusion injury evaluate the mechanism by which sevoflurane exerts this protective effect.
Fernanda Paula Cavalcante +7 more
doaj +2 more sources
Journal of Pharmacological Sciences, 2021 Objective: To investigate the effect of sevoflurane on inflammation of microglia in hippocampus of neonatal rats, and to investigate whether the related mechanism is related to Wnt/β-Catenin/CaMKIV pathway. Methods: Neonatal rats were anesthetized with 2%
Fengjuan Wang +3 more
doaj +1 more source
Comparison of emergence agitation between sevoflurane/nitrous oxide administration and sevoflurane administration alone in children undergoing adenotonsillectomy with preemptive ketorolac [PDF]
Korean Journal of Anesthesiology, 2014 BackgroundSevoflurane anesthesia commonly causes emergence agitation (EA) in children. One previous study has reported that the use of nitrous oxide (N2O) during the washout of sevoflurane may reduce EA by decreasing the residual sevoflurane ...
Ji Hye Park +6 more
doaj +1 more source
The effects of midazolam and sevoflurane on the GABA receptors with alternatively spliced variants of the γ2 subunit [PDF]
Korean Journal of Anesthesiology, 2011 BackgroundEmergence agitation after sevoflurane anesthesia in children can be prevented by midazolam. Alternative splicing of the GABAA receptor changes with age.
Woosik Eom +5 more
doaj +1 more source
The role of Volatile Anesthetics in Cardioprotection: a systematic review. [PDF]
, 2012 This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in both clinical and laboratory research and furthermore assesses possible cardiac side effects upon usage.
Applegate, Richard L +5 more
core +1 more source
EEG signals analysis using multiscale entropy for depth of anesthesia monitoring during surgery through artificial neural networks [PDF]
, 2015 In order to build a reliable index to monitor the depth of anesthesia (DOA), many algorithms have been proposed in recent years, one of which is sample entropy (SampEn), a commonly used and important tool to measure the regularity of data series. However,
Abbod, MF +4 more
core +9 more sources