Results 11 to 20 of about 57,547 (259)
Frontiers in Cell and Developmental Biology, 2022 Background: Alzheimer’s disease (AD) is the most common form of dementia worldwide. Previous studies have reported that sevoflurane, a frequently used anesthetic, can induce cognitive impairment in preclinical and clinical settings.
Dingyuan Tian +6 more
semanticscholar +1 more source
Frontiers in Medicine, 2022 Multiple sevoflurane exposure may result in cognitive deficits in neonatal animals. This study attempted to investigate the potential mechanism of sevoflurane-induced neurotoxicity in developing hippocampus.
Piao Zhang +3 more
semanticscholar +1 more source
Update on the Mechanism and Treatment of Sevoflurane-Induced Postoperative Cognitive Dysfunction
Frontiers in Aging Neuroscience, 2021 Sevoflurane is one of the most widely used anesthetics for the induction and maintenance of general anesthesia in surgical patients. Sevoflurane treatment may increase the incidence of postoperative cognitive dysfunction (POCD), and patients with POCD ...
Cong Wang +4 more
semanticscholar +1 more source
Mechanistic insight into sevoflurane-associated developmental neurotoxicity
Cell Biology and Toxicology, 2021 With the development of technology, more infants receive general anesthesia for surgery, other interventions, or clinical examination at an early stage after birth.
Mingyang Sun +3 more
semanticscholar +1 more source
Protective effects of sevoflurane in cerebral ischemia reperfusion injury: a narrative review
Medical Gas Research, 2021 Ischemia/reperfusion (I/R) injury is a phenomenon that the reperfusion of ischemic organs or tissues aggravates their damage, which poses a serious health threat and economic burden to the world.
Tianyu Liang +5 more
semanticscholar +1 more source
The anesthetic sevoflurane induces tau trafficking from neurons to microglia
Communications Biology, 2021 Accumulation and spread of tau in Alzheimer’s disease and other tauopathies occur in a prion-like manner. However, the mechanisms and downstream consequences of tau trafficking remain largely unknown.
Yuanlin Dong +8 more
semanticscholar +1 more source
F1000Research, 2015 Sevoflurane has been available for clinical practice for about 20 years. Nowadays, its pharmacodynamic and pharmacokinetic properties together with its absence of major adverse side effects on the different organ systems have made this drug accepted worldwide as a safe and reliable anesthetic agent for clinical practice in various settings.
Stefan De Hert, Anneliese Moerman
openaire +3 more sources
The Mechanisms of Sevoflurane-Induced Neuroinflammation
Frontiers in Aging Neuroscience, 2021 Sevoflurane is one of the most commonly used inhaled anesthetics due to its low blood gas coefficient, fast onset, low airway irritation, and aromatic smell.
Xiangfei Huang +11 more
semanticscholar +1 more source
Sevoflurane and cardioprotection [PDF]
British Journal of Anaesthesia, 2008 The authors hypothesize that the cardioprotective effect of sevoflurane administered throughout CABG operation may be time- and dose-dependent.
L. Siracusano +3 more
openaire +4 more sources
Tau Contributes to Sevoflurane-induced Neurocognitive Impairment in Neonatal Mice
Anesthesiology, 2020 Background: Sevoflurane anesthesia induces Tau phosphorylation and cognitive impairment in neonatal but not in adult mice. This study tested the hypothesis that differences in brain Tau amounts and in the activity of mitochondria–adenosine triphosphate ...
Yang Yu +13 more
semanticscholar +1 more source