Results 11 to 20 of about 58,127 (276)

The anesthetic sevoflurane induces tau trafficking from neurons to microglia

Communications Biology, 2021
Accumulation and spread of tau in Alzheimer’s disease and other tauopathies occur in a prion-like manner. However, the mechanisms and downstream consequences of tau trafficking remain largely unknown.
Yuanlin Dong, Feng Liang, Lining Huang, F. Fang, Guang Yang, R. Tanzi, Yiying Zhang, Qimin Quan, Zhongcong Xie   +8 more
semanticscholar   +1 more source

Protective effects of sevoflurane in cerebral ischemia reperfusion injury: a narrative review

Medical Gas Research, 2021
Ischemia/reperfusion (I/R) injury is a phenomenon that the reperfusion of ischemic organs or tissues aggravates their damage, which poses a serious health threat and economic burden to the world.
Tianyu Liang, Song-Yang Peng, Mian Ma, Haiying Li, Zhong Wang, Gang Chen   +5 more
semanticscholar   +1 more source

Sevoflurane Preconditioning Increases Stress Resistance via IMB-2/DAF-16 in Caenorhabditis Elegans

Dose-Response, 2022
Sevoflurane preconditioning has been proved to possess therapeutic effects on stress. However, the mechanism by which sevoflurane preconditioning protects against stress remains unclear.
Yue Cao MMed, Yongchen Cui MMed, Junling Liao MMed, Chente Gao MMed, Zhe Zhao MD, Junfeng Zhang MD   +5 more
doaj   +1 more source

Sevoflurane [PDF]

F1000Research, 2015
Sevoflurane has been available for clinical practice for about 20 years. Nowadays, its pharmacodynamic and pharmacokinetic properties together with its absence of major adverse side effects on the different organ systems have made this drug accepted worldwide as a safe and reliable anesthetic agent for clinical practice in various settings.
Stefan De Hert, Anneliese Moerman
openaire   +3 more sources

Dose of intra‐operative opioids has no impact on recurrence or survival in primary liver cancer

Cancer Medicine, Volume 11, Issue 24, Page 4927-4934, December 2022., 2022
Kaplan‐meier curves for recurrence‐free and overall survial of high‐dose and low‐dose groups. No significant difference in recurrence‐free survial (A) or overall survial (B) after surgery was noted when comparing high‐dose with low‐dose groups. Abstract Background Intra‐operative use of opioid analgesics might have an impact on cancer recurrence and ...
Liuyuan Zhao, Lei Teng, Wenhui Zhang, Shiyan Lin, Xuejiao Liu, Junzhu Dai, Hongxue Shao, Xiaoshi Li, Quan Liu, Huichao Zou   +9 more
wiley   +1 more source

The Mechanisms of Sevoflurane-Induced Neuroinflammation

Frontiers in Aging Neuroscience, 2021
Sevoflurane is one of the most commonly used inhaled anesthetics due to its low blood gas coefficient, fast onset, low airway irritation, and aromatic smell.
Xiangfei Huang, Jun Ying, Danying Yang, P. Fang, Xifeng Wang, Bin Zhou, Lieliang Zhang, Yang Fang, Wen Yu, Xing Liu, Qingcui Zhen, Fuzhou Hua   +11 more
semanticscholar   +1 more source

A companion to the preclinical common data elements and case report forms for in vivo rodent neuroimaging: A report of the TASK3‐WG3 Neuroimaging Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet, Riikka Immonen, Ofer Prager, Alon Friedman, Jens P. Bankstahl, David K. Wright, Terence J. O'Brien, Heidrun Potschka, Olli Gröhn, Neil G. Harris   +9 more
wiley   +1 more source

NUDT21 relieves sevoflurane-induced neurological damage in rats by down-regulating LIMK2

Open Life Sciences, 2023
Postoperative cognitive dysfunction (POCD) is a common complication of cognitive decline after surgery and anesthesia. Sevoflurane, as a commonly used anesthetic, was found to cause POCD. Nudix Hydrolase 21 (NUDT21), a conserved splicing factor, has been
Zhong Yuanping, Zhao Pengcheng, Zhang Chao, Wu Zhenyu, Fang Xu, Zhu Zhaoqiong   +5 more
doaj   +1 more source

Sevoflurane and cardioprotection [PDF]

British Journal of Anaesthesia, 2008
The authors hypothesize that the cardioprotective effect of sevoflurane administered throughout CABG operation may be time- and dose-dependent.
L. Siracusano, V. Girasole, V. Piriou, J. Mantz   +3 more
openaire   +4 more sources

Inhibition of Adult Hippocampal Neurogenesis Plays a Role in Sevoflurane-Induced Cognitive Impairment in Aged Mice Through Brain-Derived Neurotrophic Factor/Tyrosine Receptor Kinase B and Neurotrophin-3/Tropomyosin Receptor Kinase C Pathways

Frontiers in Aging Neuroscience, 2022
Sevoflurane anesthesia induces cognitive impairment, which may lead to perioperative neurocognitive disorders (PND). However, the factors and molecular mechanism underlying this impairment remains unclear.
Lichi Xu, Yanjing Guo, Yanjing Guo, Gongming Wang, Gongming Wang, Guoqing Sun, Guoqing Sun, Wei Sun, Wei Sun, Jingjing Li, Xinlei Li, Jiangnan Wu, Mengyuan Zhang, Mengyuan Zhang   +13 more
doaj   +1 more source