Results 21 to 30 of about 65,541 (293)

Sevoflurane Preconditioning Increases Stress Resistance via IMB-2/DAF-16 in Caenorhabditis Elegans

Dose-Response, 2022
Sevoflurane preconditioning has been proved to possess therapeutic effects on stress. However, the mechanism by which sevoflurane preconditioning protects against stress remains unclear.
Yue Cao MMed, Yongchen Cui MMed, Junling Liao MMed, Chente Gao MMed, Zhe Zhao MD, Junfeng Zhang MD   +5 more
doaj   +1 more source

NUDT21 relieves sevoflurane-induced neurological damage in rats by down-regulating LIMK2

Open Life Sciences, 2023
Postoperative cognitive dysfunction (POCD) is a common complication of cognitive decline after surgery and anesthesia. Sevoflurane, as a commonly used anesthetic, was found to cause POCD. Nudix Hydrolase 21 (NUDT21), a conserved splicing factor, has been
Zhong Yuanping, Zhao Pengcheng, Zhang Chao, Wu Zhenyu, Fang Xu, Zhu Zhaoqiong   +5 more
doaj   +1 more source

Inhibition of Adult Hippocampal Neurogenesis Plays a Role in Sevoflurane-Induced Cognitive Impairment in Aged Mice Through Brain-Derived Neurotrophic Factor/Tyrosine Receptor Kinase B and Neurotrophin-3/Tropomyosin Receptor Kinase C Pathways

Frontiers in Aging Neuroscience, 2022
Sevoflurane anesthesia induces cognitive impairment, which may lead to perioperative neurocognitive disorders (PND). However, the factors and molecular mechanism underlying this impairment remains unclear.
Lichi Xu, Yanjing Guo, Yanjing Guo, Gongming Wang, Gongming Wang, Guoqing Sun, Guoqing Sun, Wei Sun, Wei Sun, Jingjing Li, Xinlei Li, Jiangnan Wu, Mengyuan Zhang, Mengyuan Zhang   +13 more
doaj   +1 more source

Impacts of sufentanil/remifentanil plus sevoflurane versus propofol in adults undergoing laparoscopic herniorrhaphy [PDF]

Am J Transl Res
Fabin Huang
openalex   +2 more sources

Direct and specific effect of sevoflurane anesthesia on rat Per2 expression in the suprachiasmatic nucleus. [PDF]

PLoS ONE, 2013
BACKGROUND: Our previous studies revealed that application of the inhalation anesthetic, sevoflurane, reversibly repressed the expression of Per2 in the mouse suprachiasmatic nucleus (SCN). We aimed to examine whether sevoflurane directly affects the SCN.
Megumi Anzai, Norio Iijima, Shimpei Higo, Ken Takumi, Izumi Matsuo, Keisuke Mori, Yumiko Ohe, Kana Kadota, Toshio Akimoto, Atsuhiro Sakamoto, Hitoshi Ozawa   +10 more
doaj   +1 more source

Sevoflurane

British Journal of Anaesthesia, 1996
Sevoflurane is a fluoridated derivative of methyl isopropyl ether. Its administration does not require the use of sophisticated vaporizers and its blood/gas partition coefficient is 0.69. Sevoflurane is the only ethereal anesthesia that does not trigger a reflex response or cause airway irritation during inhaled induction.
F, Gilsanz, R, Celemín, G, Blanc, M M, Orts   +3 more
openaire   +4 more sources

The Effect of Sevoflurane Plus Propofol on Pain and Complications after Laminectomy: A Randomized Double Blind Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Pain is one of the most important reasons for the patients concern after surgery. The perfect sedative should have properties like rapid onset, least pain and adverse effects.
Aminolah Vasigh, Fatemeh Najafi, Molouk Jaafarpour, Javaher Khajavikhan, Ali Khani   +4 more
doaj   +1 more source

Cognitive dysfunction following desflurane versus sevoflurane general anesthesia in elderly patients: a randomized controlled trial. [PDF]

, 2014
UnlabelledAs life expectancy increases, more patients ≥65 years undergo general anesthesia. Anesthetic agents may contribute to postoperative cognitive dysfunction, and incidence may differ with anesthetic agents or intraoperative anesthesia depth ...
Allard, Martin, Anderson, Donald, Applegate, Richard L, Azer, Sherif, Kim, Amy, Mehdizadeh, Ali, Meineke, Minhthy, Rasmussen, Thomas   +7 more
core   +1 more source

Neuroprotective effects of sevoflurane against electromagnetic pulse-induced brain injury through inhibition of neuronal oxidative stress and apoptosis. [PDF]

PLoS ONE, 2014
Electromagnetic pulse (EMP) causes central nervous system damage and neurobehavioral disorders, and sevoflurane protects the brain from ischemic injury. We investigated the effects of sevoflurane on EMP-induced brain injury.
Bin Deng, Hao Xu, Jin Zhang, Jin Wang, Li-Chun Han, Li-Ya Li, Guang-Li Wu, Yan-Ning Hou, Guo-Zhen Guo, Qiang Wang, Han-Fei Sang, Li-Xian Xu   +11 more
doaj   +1 more source

PEX5R/Trip8b-HCN2 channel regulating neuroinflammation involved in perioperative neurocognitive disorders

Cell & Bioscience, 2022
Background Clinical and animal studies demonstrated that neuroinflammation from anesthesia (sevoflurane) is the main contributor to cause perioperative neurocognitive disorders (PND).
Feng Xu, Yafeng Wang, Linlin Han, Daling Deng, Yuanyuan Ding, LuLin Ma, Qingtong Zhang, Xiangdong Chen   +7 more
doaj   +1 more source