Results 31 to 40 of about 85,306 (297)

Neuroprotective effects of sevoflurane against electromagnetic pulse-induced brain injury through inhibition of neuronal oxidative stress and apoptosis. [PDF]

PLoS ONE, 2014
Electromagnetic pulse (EMP) causes central nervous system damage and neurobehavioral disorders, and sevoflurane protects the brain from ischemic injury. We investigated the effects of sevoflurane on EMP-induced brain injury.
Bin Deng, Hao Xu, Jin Zhang, Jin Wang, Li-Chun Han, Li-Ya Li, Guang-Li Wu, Yan-Ning Hou, Guo-Zhen Guo, Qiang Wang, Han-Fei Sang, Li-Xian Xu   +11 more
doaj   +1 more source

Resveratrol Mitigates Sevoflurane-Induced Neurotoxicity by the SIRT1-Dependent Regulation of BDNF Expression in Developing Mice

Oxidative Medicine and Cellular Longevity, 2020
Various lines of evidence suggest that neonatal exposure to general anesthetics, especially repeatedly, results in neuropathological brain changes and long-term cognitive impairment.
Xiaole Tang, Yilin Zhao, Zhi-qiang Zhou, Jing Yan, Biyun Zhou, Xiaohui Chi, A. Luo, Shiyong Li   +7 more
semanticscholar   +1 more source

Sevoflurane suppresses cell viability and invasion and promotes cell apoptosis in colon cancer by modulating exosome-mediated circ-HMGCS1 via the miR-34a-5p/SGPP1 axis

Oncology Report, 2020
As a novel halogenated hydroxyl ether-inhaled general anesthetic, sevoflurane has been reported to affect the progression of diverse human cancers. In the present study, we aimed to explore the functions and underlying mechanisms of sevoflurane in colon ...
Juan He, Huaping Zhao, Xing Liu, Dongmei Wang, Yong Wang, Yanqiu Ai, Jianjun Yang   +6 more
semanticscholar   +1 more source

Influence of the sevoflurane concentration on the occurrence of epileptiform EEG patterns.

PLoS ONE, 2014
Objectives and aimThis study was performed to analyse the effects of different sevoflurane concentrations on the incidence of epileptiform EEG activity during induction of anaesthesia in children in the clinical routine.BackgroundIt was suggested in the ...
Ines Kreuzer, W Alexander Osthaus, Arthur Schultz, Barbara Schultz   +3 more
doaj   +1 more source

Do Complexity Measures of Frontal EEG Distinguish Loss of Consciousness in Geriatric Patients Under Anesthesia? [PDF]

, 2018
While geriatric patients have a high likelihood of requiring anesthesia, they carry an increased risk for adverse cognitive outcomes from its use. Previous work suggests this could be mitigated by better intraoperative monitoring using indexes defined by
Caitlin M. Drover, David R. Drover, Don A. Vaughn, Don A. Vaughn, M. Bruce MacIver, Mark S. Cohen, Mark S. Cohen, Nicholas T. Ouellette, Sarah L. Eagleman   +8 more
core   +2 more sources

Sevoflurane anesthesia ameliorates LPS-induced acute lung injury (ALI) by modulating a novel LncRNA LINC00839/miR-223/NLRP3 axis

BMC Pulmonary Medicine, 2022
Background Sevoflurane is considered as a lung-protective factor in acute lung injury (ALI), but the underlying molecular mechanism remains largely unknown.
Zhiling Fu, Xiuying Wu, Fushuang Zheng, Yan Zhang   +3 more
doaj   +1 more source

Dexmedetomidine and Clonidine Attenuate Sevoflurane-Induced Tau Phosphorylation and Cognitive Impairment in Young Mice via α-2 Adrenergic Receptor.

Anesthesia and Analgesia, 2020
BACKGROUND Anesthetic sevoflurane induces tau phosphorylation and cognitive impairment in young mice. The underlying mechanism and the targeted interventions remain largely unexplored.
Mingyang Sun, Yuanlin Dong, Mengzhu Li, Yiying Zhang, Feng Liang, Iaqiang Zhang, S. Soriano, Zhongcong Xie   +7 more
semanticscholar   +1 more source

Sevoflurane postconditioning improves spatial learning and memory ability involving mitochondrial permeability transition pore in hemorrhagic shock and resuscitation rats

Brain and Behavior, 2020
Background Hemorrhagic shock induces the cognitive deficiency. Sevoflurane postconditioning has been documented to provide neuroprotection against ischemic–reperfusion injury by suppressing apoptosis.
Li Zhang, Li Huang, Jingxian Wang, Muchun Zhang, Ye Zhang, Xianwen Hu   +5 more
doaj   +1 more source

Impact of Sevoflurane and Thiopental Used Over the Course of Electroconvulsive Therapy: Propensity Score Matching Analysis

Frontiers in Human Neuroscience, 2022
ObjectiveAlthough anesthetics play an important role in electroconvulsive therapy (ECT), the clinical efficacy and seizure adequacy of sevoflurane in the course of ECT remain unclear.
Taisuke Yatomi, Takahito Uchida, Takahito Uchida, Akihiro Takamiya, Masataka Wada, Shun Kudo, Kazuki Nakajima, Hana Nishida, Bun Yamagata, Masaru Mimura, Jinichi Hirano   +10 more
doaj   +1 more source

Inhalational or total intravenous anaesthesia: is total intravenous anaesthesia useful and are there economic benefits? [PDF]

, 2011
PURPOSE OF REVIEW: The comparison of inhalational and intravenous anaesthesia has been the subject of many controlled trials and meta-analyses. These reported diverse endpoints typically including measures of the speed and quality of induction of ...
Holmes, KA, Sneyd, JR
core   +1 more source