Results 51 to 60 of about 65,541 (293)

Janus Kinase Mediates Faster Recovery From Sevoflurane Anesthesia Than Isoflurane Anesthesia in the Migratory Locusts

Frontiers in Physiology, 2022
Inhalation anesthetics isoflurane and sevoflurane have been widely used in clinical practice for anesthesia. However, the molecular mechanisms underlying the faster recovery from sevoflurane anesthesia than isoflurane anesthesia remain largely ...
Zongyuan Ma, Jialin C. Zheng, Tianzuo Li, Zhongcong Xie, Le Kang   +4 more
doaj   +1 more source

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

Advanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li, Chang Liu, Zhaoxue Ma, Dongyou Zheng, Renkai Wang, Yongjing Yu, Guangmin Chen, Chenglong Li, Yue Bu, Hang Cao, Bing Zhang   +10 more
wiley   +1 more source

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng, Shuangyu Liu, Yu Zhang, Kang Peng, Muge Qile, Chao Wu, Mengyun Dou, Liu Liu, Na Yang, Rui Liu, Guiyang Zhang, Liangping Ni, Gaolin Liang, Fang Yang, Ye Zhang, Shufang He   +15 more
wiley   +1 more source

Sevoflurane Does Not Promote the Colony-Forming Ability of Human Mesenchymal Glioblastoma Stem Cells In Vitro

Medicina, 2022
Background and Objectives: Clinically used concentrations of sevoflurane, an inhaled anesthetic, have been reported to significantly inhibit tumor growth.
Tomohiro Shoji, Mikio Hayashi, Chisato Sumi, Munenori Kusunoki, Takeo Uba, Yoshiyuki Matsuo, Kiichi Hirota   +6 more
doaj   +1 more source

Anesthesia in the surgery of strabismus: role of anesthetic agents in the ocular deviation and surgical outcome [PDF]

, 2015
Purpose: To determine whether the changes in the ocular alignment following general anesthesia, maintained with two different inhalational anesthetic agents, sevoflurane and desflurane, can be used as a predictor for surgical outcomes in children with ...
Arrico, Loredana, Cannata, Riccardo, Collini, Saul, Malagola, Romualdo, Migliorini, Raffaele, Servidio, Annalisa   +5 more
core   +1 more source

Role of potassium and calcium channels in sevoflurane-mediated vasodilation in the foeto-placental circulation

BMC Anesthesiology, 2009
Background Sevoflurane has been demonstrated to vasodilate the foeto-placental vasculature. We aimed to determine the contribution of modulation of potassium and calcium channel function to the vasodilatory effect of sevoflurane in isolated human ...
Jarman James, Maharaj Chrisen H, Higgins Brendan D, Farragher Rachel F, Laffey Christopher D, Flynn Noel M, Laffey John G   +6 more
doaj   +1 more source

The usefulness of intraoperative electrocorticography (iECoG) in pediatric temporal lobe epilepsy surgery

Epileptic Disorders, EarlyView.
Abstract Objective This study aimed to evaluate the usefulness of intraoperative electrocorticography (iECoG) in providing a more accurate surgical strategy, thereby yielding seizure freedom following resective surgery in children with temporal lobe epilepsy (TLE).
Rafael Andrade Cruz, João Paulo Sant’ Ana Santos de Souza, Davi Casale Aragon, Úrsula Thomé Costa, Ana Paula Andrade Hamad, Américo Ceiki Sakamoto, Antônio Carlos dos Santos, Hélio Rubens Machado, Marcelo Volpon Santos   +8 more
wiley   +1 more source

Sevoflurane Inhibits Metastasis in Hepatocellular Carcinoma by Inhibiting MiR-665-Induced Activation of the ERK/MMP Pathway

Cell Transplantation, 2022
Recent evidence has indicated that inhalational anesthetics may affect the growth and malignant potential of tumor cells and ultimately influence tumor recurrence after surgery.
Xiaoyan Zhu, Chuchu Peng, Zhiyong Peng, Ruimin Chang, Qulian Guo   +4 more
doaj   +1 more source

Tracheal intubation without neuromuscular blocking drugs in children [PDF]

, 2009
No abstract ...
Aantaa, Abdallah, Aouad, Batra, Blair, Blair, Bode, Crawford, De Fatima De Assuncao Braga, Drenger, Duman, Gupta, Hansen, Hansen, Helbo-Hansen, Hiller, Humphries, Inomata, Inomata, Inomata, Inomata, Inomata, Klemola, Lerman, Meakin, Mertes, Min, Morgan, Nishina, O’Brien, Politis, Politis, Robinson, Senel, Simon, Splinter, Steyn, Swan, Taguchi, Thwaites, Wappler, Warner, Watcha, Watcha, Watcha, Watcha, Weber, Woods, Xue, Xue, Xue, Xue, Yaguchi   +52 more
core   +1 more source

Inroads into epilepsy through high‐frequency oscillations: Achievements and benchmark areas for improvement

Epilepsia, EarlyView.
Abstract High‐frequency oscillations (HFOs) were discovered more than 20 years ago, and since then they have been studied intensively in the context of epilepsy. HFOs encompass a broad spectrum of oscillations, typically ranging from 80 Hz to several kHz, that include both normal and pathological oscillations, documented in people with epilepsy and ...
Christos Panagiotis Lisgaras, Birgit Frauscher, Jean Gotman, Julia Jacobs, Philippe Kahane, Richard J. Staba, Maeike Zijlmans   +6 more
wiley   +1 more source