Results 81 to 90 of about 1,582,592 (296)

Fast evolutionary turnover and overlapping variances of sex-biased gene expression patterns defy a simple binary sex classification of somatic tissues

eLife
Sexual dimorphism in phenotypes is largely driven by genes with sex-biased expression, spanning from key regulators to numerous organ-specific effectors.
Chen Xie, Sven Künzel, Diethard Tautz
doaj   +1 more source

Strain specific effects of low level lead exposure on associative learning and memory in rats. [PDF]

, 2017
Exposure to lead (Pb) remains a significant public health concern. Lead exposure in early life impairs the normal development of numerous cognitive and neurobehavioral processes.
Schneider, J. S., Verma, Megha
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting nitric oxide bioavailability [PDF]

, 2017
Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting nitric oxide bioavailability. Am J Physiol Renal Physiol 313: F174 –F183, 2017.
Chen, Ying, Edwards, Aurelie, Layton, Anita T., Sullivan, Jennifer C.   +3 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Evolutionary and developmental dynamics of sex-biased gene expression in common frogs with proto-Y chromosomes

Genome Biology, 2018
Background The patterns of gene expression on highly differentiated sex chromosomes differ drastically from those on autosomes, due to sex-specific patterns of selection and inheritance.
Wen-Juan Ma, Paris Veltsos, Roberto Sermier, Darren J Parker, Nicolas Perrin   +4 more
doaj   +1 more source

Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer [PDF]

, 2019
Background. Fibronectin type III domain-containing (FNDC) proteins fulfill manifold functions in tissue development and regulation of cellular metabolism.
Adler, Andreas, Aigner, Felix, Becker, Olaf, Biebl, Matthias, Bosma, Madeleen, Pratschke, Johann, Quint, Janina, Spitz, Wolfgang, Stockmann, Martin, Veltzke-Schlieker, Wilfried, Weiss, Sascha, Wizenty, Jonas, Wuensch, Tilo   +12 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Sex differences in basal hypothalamic anorectic and orexigenic gene expression and the effect of quantitative and qualitative food restriction [PDF]

, 2018
Background Research into energy balance and growth has infrequently considered genetic sex, yet there is sexual dimorphism for growth across the animal kingdom.
A Heck, AP Arnold, BJ Tolkamp, BK Podisi, BL Nielsen, C Zhang, CJ Savory, D Amadon, D Huszar, D Rigaud, D Zhao, E Decuypere, G Grabauskas, G Maniatis, GB Havenstein, GJ Davies, H Hara, Health EPoA, Welfare, IC De Jong, IC De Jong, IC Dunn, IC Dunn, IC Dunn, J Chue, J Zhang, JA Mench, JJ Lees, JM Brum, JW McRorie Jr, K Ralls, L Lei, L Wang, L Yuan, LG Frank, LK Burke, LM Dixon, M Andersson, M Clinton, M Graham, M Mohammadrezaei, M Perez-Miranda, MJ Fennell, MK Ling, N Goto, N Loganathan, OA Tashani, P Lal, PM Hocking, PM Hocking, R Guillot, R Sears, RJ Agate, T Boswell, T Boswell, T Tachibana, T Tachibana, TM Hahn, V Remes, V Sandilands, V Sandilands, XQ Chen, Z Song   +61 more
core   +2 more sources

Sex expression in spinach

Hilgardia, 1925
Abstract does not appear. First page follows. As would be expected in a dioecious, wind-pollinized plant, existing varieties of spinach are in general in a highly heterozygous condition. Commercial stocks are frequently of mixed varieties, of unsuitable types, or incorrectly named.
openaire   +2 more sources