Results 41 to 50 of about 641 (96)
Viruses, 2018 The RNA3 species of the beet necrotic yellow vein virus (BNYVV), a multipartite positive-stranded RNA phytovirus, contains the ‘core’ nucleotide sequence required for its systemic movement in Beta macrocarpa.
Alyssa Flobinus +9 more
doaj +1 more source
WIREs RNA, Volume 16, Issue 2, March/April 2025.Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus +3 more
wiley +1 more source
Health Science Reports, Volume 7, Issue 10, October 2024.Abstract Background and aims Hyperglycemia, also known as diabetes, is a metabolic disorder characterized by elevated levels of glucose in the bloodstream. It can lead to the prolonged dysfunction, injury, and deterioration of several organs. In addition, dengue is a viral illness transmitted by mosquitoes that has reached epidemic proportions ...
Shandipon Roy Shawon +4 more
wiley +1 more source
, 2019 ZIka virus (ZIKV) is a single-stranded positive sense RNA flavivirus that is transmitted primarily by Aedes aegypti. To date, all vector-borne flaviviruses are known to generate stable subgenomic flavivirus RNAs (sfRNA), due to the stalling of the major cytoplasmic 5'-3' exoribonuclease XRN1 at a knot-like three helix junction structure located in ...
Ontiveros Valles, Jesús Gustavo, author +3 more
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Mechanism and structural diversity of exoribonuclease-resistant RNA structures in flaviviral RNAs
Nature Communications, 2018 Subgenomic flavivirus RNAs are generated by a host exoribonuclease and play an important role in virus replication and pathogenesis. Here, the authors show the mechanism by which subgenomic flavivirus RNAs are generated and identify two structurally ...
Andrea MacFadden +8 more
doaj +1 more source
Comparative analysis of sfRNA in the genome of pre-epidemic and epidemic Zika viruses for host interacting proteins potentially related to the recent epidemic [PDF]
, 2019 Abstract Zika virus (ZIKV), circulating in more than 70 countries since 2014, is causing severe developmental abnormality to compare to pre-epidemic infection. ZIKV related flaviviruses as the ability to produce subgenomic flaviviral RNAs (sfRNAs) which are associated with pathogenicity in foetal mice.
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The 5′ and 3′ Untranslated Regions of the Flaviviral Genome
Viruses, 2017 Flaviviruses are enveloped arthropod-borne viruses with a single-stranded, positive-sense RNA genome that can cause serious illness in humans and animals.
Wy Ching Ng +4 more
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The Multiples Fates of the Flavivirus RNA Genome During Pathogenesis
Frontiers in Genetics, 2018 The Flavivirus genus comprises many viruses (including dengue, Zika, West Nile and yellow fever viruses) which constitute important public health concerns worldwide. For several of these pathogens, neither antivirals nor vaccines are currently available.
Clément Mazeaud +2 more
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Interdependent RNA structural motifs at the 3'-terminus of the West Nile virus genome regulate viral growth. [PDF]
Nucleic Acids ResTsao LH, Brackney DE, Pyle AM.
europepmc +1 more source