SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation [PDF]
Frontiers in Immunology, 2021 Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne virus that causes hemorrhagic fever. Previous studies showed that SFTSV-infected patients exhibited elevated levels of pro-inflammatory cytokines like interleukin-1β (IL ...
Jian-Wei Liu +5 more
doaj +5 more sources
CRISPR/Cas12a Technology Combined With RPA for Rapid and Portable SFTSV Detection [PDF]
Frontiers in Microbiology, 2022 Severe fever with thrombocytopenia syndrome virus (SFTSV) is a new tick-borne pathogen that can cause severe hemorrhagic fever. Fever with thrombocytopenia syndrome caused by SFTSV is a new infectious disease that has posed a great threat to public ...
Mengqian Huang +9 more
doaj +4 more sources
Pathogen isolation and traceability analysis of a fatal case of severe fever with thrombocytopenia syndrome virus (SFTSV) infectious encephalitis in China [PDF]
Virology JournalBackground The initial clinical symptoms of severe fever with thrombocytopenia syndrome (SFTS) mainly include high fever, thrombocytopenia and gastrointestinal symptoms, and severe patients may suffer from severe complications such as multiple organ ...
Rongjiao Liu +7 more
doaj +4 more sources
Seasonal dynamics of Haemaphysalis tick species as SFTSV vectors in South Korea. [PDF]
Microbiol SpectrABSTRACT Ticks pose a significant public health threat due to their ability to transmit various pathogens, including emerging tick-borne diseases. This study conducted a comprehensive surveillance of Haemaphysalis tick species and their severe fever with thrombocytopenia ...
Jang H +9 more
europepmc +5 more sources
SFTSV infection in rodents and their ectoparasitic chiggers
PLoS Neglected Tropical Diseases, 2022 SFTSV, a tick-borne bunyavirus causing a severe hemorrhagic fever termed as severe fever with thrombocytopenia syndrome (SFTS). To evaluate the potential role of rodents and its ectoparasitic chiggers in the transmission of SFTSV, we collected wild ...
Xiao-Lan Gu +14 more
doaj +4 more sources
SFTSV infection is associated with transient overproliferation of monoclonal lambda-type plasma cells [PDF]
iScience, 2023 The impairment of antibody-mediated immunity is a major factor associated with fatal cases of severe fever with thrombocytopenia syndrome (SFTS). By collating the clinical diagnosis reports of 30 SFTS cases, we discovered the overproliferation of monoclonal plasma cells (MCP cells, CD38+cLambda+cKappa-) in bone marrow, which has only been reported ...
Chuansong Quan +18 more
openalex +4 more sources
An emerging hemorrhagic fever in China caused by a novel bunyavirus SFTSV [PDF]
Science China Life Sciences, 2013 Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever in rural areas of China and is caused by a new bunyavirus, SFTSV, named after the disease. The transmission vectors and animal hosts of SFTSV are unclear. Ticks are the most likely transmission vectors and domestic animals, including goats, dogs, and cattle, are ...
XiaoShuang Zhang +6 more
openalex +3 more sources
Molecular mechanism and structure-guided humanization of a broadly neutralizing antibody against SFTSV. [PDF]
PLoS PathogensSevere fever with thrombocytopenia syndrome virus (SFTSV) is a novel tick-borne bunyavirus that causes severe fever with thrombocytopenia syndrome (SFTS), with a high mortality rate of up to 30%.
Pinyi Yang +10 more
doaj +4 more sources
Two Different Strains of Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) in North and South Osaka by Phylogenetic Analysis of Evolutionary Lineage: Evidence for Independent SFTSV Transmission [PDF]
Viruses, 2021 Severe fever with thrombocytopenia syndrome (SFTS) is a novel tick-borne infectious disease, therefore, the information on the whole genome of the SFTS virus (SFTSV) is still limited. This study demonstrates a nearly whole genome of the SFTSV identified in Osaka in 2017 and 2018 by next-generation sequencing (NGS).
Ryo Ikemori +8 more
openalex +6 more sources
Virology Journal, 2023 Background Severe fever with thrombocytopenia syndrome (SFTS) is an infectious disease caused by the Dabie bandavirus, [or SFTS virus (SFTSV)] that has become increasingly widespread since it was first reported in 2009.
Kyungha Lee +4 more
doaj +3 more sources