Results 1 to 10 of about 4,025 (237)

Pathogen isolation and traceability analysis of a fatal case of severe fever with thrombocytopenia syndrome virus (SFTSV) infectious encephalitis in China [PDF]

Virology Journal
Background The initial clinical symptoms of severe fever with thrombocytopenia syndrome (SFTS) mainly include high fever, thrombocytopenia and gastrointestinal symptoms, and severe patients may suffer from severe complications such as multiple organ ...
Rongjiao Liu, Fangling He, Shengbao Chen, Juan Wang, Chan Yang, Zhifei Zhan, Yaru Xiong, Liang Cai   +7 more
doaj   +5 more sources

CRISPR/Cas12a Technology Combined With RPA for Rapid and Portable SFTSV Detection [PDF]

Frontiers in Microbiology, 2022
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a new tick-borne pathogen that can cause severe hemorrhagic fever. Fever with thrombocytopenia syndrome caused by SFTSV is a new infectious disease that has posed a great threat to public ...
Mengqian Huang, Sihua Liu, Yanan Xu, Aqian Li, Wei Wu, Mifang Liang, Guoyu Niu, Zhiyun Wang, Tao Wang, Tao Wang   +9 more
doaj   +5 more sources

Genome-wide CRISPR screening identifies LRP1 as an entry factor for SFTSV. [PDF]

Nat Commun
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease caused by the SFTS virus (SFTSV), which has high mortality rates and poses a significant threat to public health. To identify potential therapeutic targets against SFTSV,
Xing C, Zhang C, Xu Z, Wang Y, Lu W, Liu X, Zhang Y, Ma J, Yang S, Du Y, Xu G, Liu Y.   +11 more
europepmc   +6 more sources

SFTSV infection in rodents and their ectoparasitic chiggers

PLoS Neglected Tropical Diseases, 2022
SFTSV, a tick-borne bunyavirus causing a severe hemorrhagic fever termed as severe fever with thrombocytopenia syndrome (SFTS). To evaluate the potential role of rodents and its ectoparasitic chiggers in the transmission of SFTSV, we collected wild ...
Xiao-Lan Gu, Wen-Qing Su, Chuan-Min Zhou, Li-Zhu Fang, Ke Zhu, Dong-Qiang Ma, Fa-Chun Jiang, Ze-Min Li, Dan Li, Shu-Hui Duan, Qiu-Ming Peng, Rui Wang, Yuan Jiang, Hui-Ju Han, Xue-Jie Yu   +14 more
doaj   +5 more sources

SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation [PDF]

Frontiers in Immunology, 2021
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne virus that causes hemorrhagic fever. Previous studies showed that SFTSV-infected patients exhibited elevated levels of pro-inflammatory cytokines like interleukin-1β (IL ...
Jian-Wei Liu, Min Chu, Yong-jun Jiao, Chuan-Min Zhou, Rui Qi, Xue-jie Yu   +5 more
doaj   +5 more sources

Development of ¹¹¹In-Labeled Monoclonal Antibodies Targeting SFTSV Structural Proteins for Molecular Imaging of SFTS Infectious Diseases by SPECT. [PDF]

Molecules
No effective vaccines or treatments are currently available for severe fever with thrombocytopenia syndrome (SFTS), a fatal tick-borne infectious disease caused by the SFTS virus (SFTSV).
Fuchigami T, Ngwe Tun MM, Tanahara Y, Nishi K, Yoshida S, Ogawa K, Nakayama M, Hayasaka D.   +7 more
europepmc   +3 more sources

Two Point Mutations in the Glycoprotein of SFTSV Enhance the Propagation Recombinant Vesicular Stomatitis Virus Vectors at Assembly Step [PDF]

Viruses, 2023
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne pathogen for which approved therapeutic drugs or vaccines are not available.
Qiang Hu, Yuhang Zhang, Jia-Fu Jiang, Aihua Zheng   +3 more
openalex   +2 more sources

Non-Structural Protein-W61 as a Novel Target in Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV): An In-Vitro and In-Silico Study on Protein-Protein Interactions with Nucleoprotein and Viral Replication [PDF]

Viruses, 2023
The non-structural protein (NSs) and nucleoprotein (NP) of the severe fever with thrombocytopenia syndrome virus (SFTSV) encoded by the S segment are crucial for viral pathogenesis.
Ji-Young Park, Chandran Sivasankar, Perumalraja Kirthika, Dhamodharan Prabhu, John Hwa Lee   +4 more
openalex   +2 more sources

SFTSV Gn‐Head mRNA vaccine confers efficient protection against lethal viral challenge [PDF]

Journal of Medical Virology, 2023
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick‐borne virus, causing thrombocytopenia and hemorrhagic fever, with a fatality rate ranging from 12% to 30%.
Do-Kyun Kim, Chih‐Jen Lai, In‐Ho Cha, Seokmin Kang, Wan‐Shan Yang, Younho Choi, Jae U. Jung   +6 more
openalex   +2 more sources

Distribution of Tick Vectors of Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) Collected from Four Environments in Jeju

Korean Journal of Clinical Laboratory Science, 2020
The distribution of ticks and severe fever with thrombocytopenia syndrome virus (SFTSV) pathogens were investigated by collecting ticks from March to November 2018 in four environments (grass fields, copses, mountain roads, and tombs) in Jeju.
Kyoung A Chung, Hyeon Je Song, Hyeok Jae Lee, Chul Park, Min Yeung Seo   +4 more
doaj   +3 more sources