Results 31 to 40 of about 3,555 (225)

Molecular mechanism and structure-guided humanization of a broadly neutralizing antibody against SFTSV.

PLoS Pathogens
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel tick-borne bunyavirus that causes severe fever with thrombocytopenia syndrome (SFTS), with a high mortality rate of up to 30%.
Pinyi Yang, Xiaoli Wu, Hang Shang, Zixian Sun, Zhiying Wang, Zidan Song, Hong Yuan, Fei Deng, Shu Shen, Yu Guo, Nan Zhang   +10 more
doaj   +3 more sources

Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress [PDF]

Autophagy, 2021
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging negatively stranded enveloped RNA bunyavirus that causes SFTS with a high case fatality rate of up to 30%. Macroautophagy/autophagy is an evolutionarily conserved process involved in the maintenance of host homeostasis, which exhibits anti-viral or pro-viral responses in reaction ...
Yan, Jia-min, Zhang, Wen-kang, Yan, Li-na, Jiao, Yong-Jun, Zhou, Chuan-min, Yu, Xue-jie   +5 more
openaire   +2 more sources

SFTSV Prevalence in Ticks and Livestock in an SFTSV-Endemic Area in Central China. [PDF]

Pathogens
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne bunyavirus that causes a severe viral hemorrhagic fever (SFTS), with a very high case mortality rate, expanding epidemic areas, and increasing incidence. Due to the lack of an effective drug or vaccine for SFTS, reducing the incidence and mortality of SFTS primarily ...
Lu HY, Wu GD, Peng M, Wu LB, Luo YM, Xia B, Xiong D, Qin XR, Guo F, Yu XJ.   +9 more
europepmc   +2 more sources

Immunization with Recombinant SFTSV/NSs Protein Does Not Promote Virus Clearance in SFTSV-Infected C57BL/6J Mice [PDF]

Viral Immunology, 2015
The severe fever with thrombocytopenia syndrome (SFTS), caused by a novel Phlebovirus in the Bunyaviridae family named SFTS virus (SFTSV), is an emerging hemorrhagic fever with a wide distribution and high case-fatality rate. Neither effective treatment nor vaccines are available to treat and prevent this disease to date.
Rong, Liu, Dou-Dou, Huang, Jie-Ying, Bai, Lu, Zhuang, Qing-Bin, Lu, Xiao-Ai, Zhang, Wei, Liu, Jing-Yu, Wang, Wu-Chun, Cao   +8 more
openaire   +2 more sources

Reactivation of Epstein-Barr virus in SFTSV infected patients

Infectious Medicine, 2023
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever caused by a tick-borne bunyavirus SFTSV with case fatality up to 30%. The reactivation of Epstein-Barr virus (EBV) has been proven to occur in individuals with various immune suppression conditions.Here, we diagnosed 22 SFTSV infected patients with PCR in a hospital in ...
Li-Zhu Fang, Yu-Hong Dong, Zhi-Jian Yan, Chuan-Min Zhou, Xue-Jie Yu, Xiang-Rong Qin   +5 more
openaire   +3 more sources

Severe fever with thrombocytopenia syndrome virus trends and hotspots in clinical research: A bibliometric analysis of global research

Frontiers in Public Health, 2023
BackgroundSince severe fever with thrombocytopenia syndrome virus (SFTSV) was first reported in 2009, a large number of relevant studies have been published. However, no bibliometrics analysis has been conducted on the literature focusing on SFTSV.
Zhengyu Zhang, Juntao Tan, Wen Jin, Hong Qian, Loulei Wang, Hu Zhou, Yuan Yuan, Xiaoxin Wu   +7 more
doaj   +1 more source

Ecology of the Tick-Borne Phlebovirus Causing Severe Fever with Thrombocytopenia Syndrome in an Endemic Area of China. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Severe fever with thrombocytopenia syndrome (SFTS) is caused by SFTS virus (SFTSV), a tick-borne phlebovirus in family Bunyaviridae. Studies have found that humans, domestic and wildlife animals can be infected by SFTSV.
Zhifeng Li, Changjun Bao, Jianli Hu, Wendong Liu, Xiaochen Wang, Lei Zhang, Zhengmin Ji, Zhi Feng, Luxun Li, Aihua Shen, Xuejian Liu, Hongjun Zhao, Wenwen Tan, Jiangang Zhou, Xian Qi, Yefei Zhu, Fenyang Tang, Carol J Cardona, Zheng Xing   +18 more
doaj   +1 more source

M Segment-Based Minigenome System of Severe Fever with Thrombocytopenia Syndrome Virus as a Tool for Antiviral Drug Screening

Viruses, 2021
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne bunyavirus that causes severe disease in humans with case fatality rates of approximately 30%. There are few treatment options for SFTSV infection. SFTSV RNA synthesis is
Hiroshi Yamada, Satoshi Taniguchi, Masayuki Shimojima, Long Tan, Miyuki Kimura, Yoshitomo Morinaga, Takasuke Fukuhara, Yoshiharu Matsuura, Takashi Komeno, Yousuke Furuta, Masayuki Saijo, Hideki Tani   +11 more
doaj   +1 more source

A Focus on the Mechanisms of Alteration in Host Lymphocyte Level Following Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) Infection. [PDF]

J Inflamm Res
Chen Y, Miller H, Benlagha K, Byazrova MG, Filatov AV, Zhang Z, Liu L, Ding Y, Yang L, Gong Q, Liu C.   +10 more
europepmc   +3 more sources

Epidemiologic Features and Environmental Risk Factors of Severe Fever with Thrombocytopenia Syndrome, Xinyang, China [PDF]

, 2014
Background:Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease discovered in rural areas of Central China in 2009, caused by a novel bunyavirus ...
Cao, W.-C. (Wu-Chun), Cui, N. (Ning), Fang, L.Q. (Lily), Gray, G.C. (Gregory), Li, H. (Hao), Liang, S. (Song), Liu, K. (Kun), Liu, W. (Wei), Lu, Q.-B. (Qing-Bin), Peng, W. (Wei), Vlas, S.J. (Sake) de, Wang, B.-J. (Bing-Jun), Wang, H.-Y. (Hong-Yu), Wang, L.-Y. (Li-Yuan), Yang, H. (Hong), Zhang, Y.-Y. (Yao-Yun), Zhuang, L. (Lu)   +16 more
core   +9 more sources