Results 61 to 70 of about 4,025 (237)

Immunization with Recombinant SFTSV/NSs Protein Does Not Promote Virus Clearance in SFTSV-Infected C57BL/6J Mice [PDF]

Viral Immunology, 2015
The severe fever with thrombocytopenia syndrome (SFTS), caused by a novel Phlebovirus in the Bunyaviridae family named SFTS virus (SFTSV), is an emerging hemorrhagic fever with a wide distribution and high case-fatality rate. Neither effective treatment nor vaccines are available to treat and prevent this disease to date.
Jie-Ying Bai, Wei Liu, Jing-Yu Wang, Lu Zhuang, Qing-Bin Lu, Rong Liu, Xiao-Ai Zhang, Dou-Dou Huang, Wu-Chun Cao   +8 more
openaire   +3 more sources

Ecology of the Tick-Borne Phlebovirus Causing Severe Fever with Thrombocytopenia Syndrome in an Endemic Area of China. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Severe fever with thrombocytopenia syndrome (SFTS) is caused by SFTS virus (SFTSV), a tick-borne phlebovirus in family Bunyaviridae. Studies have found that humans, domestic and wildlife animals can be infected by SFTSV.
Zhifeng Li, Changjun Bao, Jianli Hu, Wendong Liu, Xiaochen Wang, Lei Zhang, Zhengmin Ji, Zhi Feng, Luxun Li, Aihua Shen, Xuejian Liu, Hongjun Zhao, Wenwen Tan, Jiangang Zhou, Xian Qi, Yefei Zhu, Fenyang Tang, Carol J Cardona, Zheng Xing   +18 more
doaj   +1 more source

Lactate Dehydrogenase/Albumin to Urea Ratio: A Novel Prognostic Indicator for Adverse Outcomes in Patients With Severe Fever With Thrombocytopenia Syndrome [PDF]

J Med Virol
ABSTRACT Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease with significant mortality risks. This study evaluated the predictive value of the lactate dehydrogenase/albumin to urea ratio (LAU) for lethal outcomes in SFTS patients.
Zhang R, Mu Y, Zhang M, Wu H, Xu Y, Zhao C, Liu Z, Lin L, Zhang W, Kong Y, Chen Z.   +10 more
europepmc   +2 more sources

The SFTSV Nonstructural Proteins Induce Autophagy to Promote Viral Replication via Interaction with Vimentin

Journal of Virology, 2023
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a newly emerging tick-borne pathogen that causes multifunctional organ failure and even death in humans.
Sihua Liu, Yazhi Su, Zhuozhuang Lu, X. Zou, Leling Xu, Yue Teng, Zhiyun Wang, Tao Wang   +7 more
semanticscholar   +1 more source

Mapping of transcription termination within the S segment of SFTS phlebovirus facilitated the generation of NSs-deletant viruses [PDF]

, 2017
SFTS phlebovirus (severe fever with thrombocytopenia syndrome virus; SFTSV) is an emerging tick-borne bunyavirus that was first reported in China in 2009. Here we report the generation of a recombinant SFTSV (rHB29NSsKO) that cannot express the viral non-
Brennan, Benjamin, Elliott, Richard M., Rezelj, Veronica V.   +2 more
core   +1 more source

Construction and Characterization of Severe Fever with Thrombocytopenia Syndrome Virus with a Fluorescent Reporter for Antiviral Drug Screening

Viruses, 2023
Severe fever with thrombocytopenia syndrome (SFTS) caused by a novel bunyavirus (SFTSV) is an emerging infectious disease with up to 30% case fatality. Currently, there are no specific antiviral drugs or vaccines for SFTS. Here, we constructed a reporter
Xiao Wang, Mingyue Xu, Huanhuan Ke, Longda Ma, Liushuai Li, Jiang Li, Fei Deng, Manli Wang, Zhihong Hu, Jia Liu   +9 more
doaj   +1 more source

Identification and characterization of three monoclonal antibodies targeting the SFTSV glycoprotein and displaying a broad spectrum recognition of SFTSV-related viruses

PLOS Neglected Tropical Diseases
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel tick-borne viral pathogen that causes severe fever with thrombocytopenia syndrome (SFTS). The disease was initially reported in central and eastern China, then later in Japan and South Korea, with a mortality rate of 13–30%.
Xiaoli Wu, Abulimiti Moming, Yanfang Zhang, Zhi Wang, Tao Zhang, Liyan Fu, Jin Qian, Jun Ni, Sijing Hu, Shuāng Táng, Xin Zheng, Huálín Wáng, Shū Shěn, Fēi Dèng   +13 more
openalex   +4 more sources

Ultra-rapid detection of nuclear protein of severe fever with thrombocytopenia syndrome virus by colloidal gold immunochromatography assay [PDF]

PeerJ
In 2009, severe fever with thrombocytopenia syndrome virus (SFTSV), also known as the Dabie bandavirus (DBV), was first discovered in Henan, China. It is a tick-borne zoonotic virus with a fatality rate ranging from 6% to 30%. Currently, we lack safe and
Zhiwei Huang, Jianhua Li, Wentao Wei, Hongyu Li, Hao Yan, Ruyi Chen, Jiaxuan Li, Xiaotian Tie, Di Wang, Guangshang Wu, Ling Zhang, Yanjun Zhang, Keda Chen, Yongliang Lou   +13 more
doaj   +2 more sources

Novel SFTSV Phylogeny Reveals New Reassortment Events and Migration Routes [PDF]

Virologica Sinica, 2020
Severe fever with thrombocytopenia syndrome virus (SFTSV), the causative agent of a febrile human disease, was first identified from central and eastern provinces in China, and later in Japan and South Korea. Hubei Province is one of the major SFTS epidemic areas in the central part of China.
Xiaoli Wu, Mingyue Li, Yanfang Zhang, Boyun Liang, Junming Shi, Yaohui Fang, Zhengyuan Su, Mengmeng Li, Wenjing Zhang, Ling Xu, Jun Wang, Qiaoli Wu, Shuang Tang, Hualin Wang, Tao Zhang, Cheng Peng, Xin Zheng, Fei Deng, Shu Shen   +18 more
openaire   +3 more sources

Emerging phleboviruses [PDF]

, 2014
The <i>Bunyavidae</i> family is the largest grouping of RNA viruses and arguably the most diverse. Bunyaviruses have a truly global distribution and can infect vertebrates, invertebrates and plants.
Bird, Bird, Bouloy, Calisher, Chare, Chen, Crabtree, Dilcher, Ding, Elliott, Ferron, Giorgi, He, Hofmann, Hubalek, Ikegami, Ikegami, Jiao, Jin, Kim, Kokernot, Lohmeyer, Lozach, Matsuno, McMullan, Narayanan, Plyusnin, Qu, Raymond, Savage, Sibold, Stone, Swei, Takahashi, Terasaki, Weber, Won, Won, Xu, Yu, Zhang, Zhang, Zhou   +42 more
core   +2 more sources