Results 51 to 60 of about 541,953 (330)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

ALGEBRAIC EQUATIONS WITH LINEAR SHIFT OPERATORS ON SEQUENCES [PDF]

open access: yesRomanian Journal of Mathematics and Computer Science, 2016
In this note we recall (see also [8]) the structure of all recurrent sequences which satisfy a fixed recurrence relation, with entries in a perfect field.
SEVER ANGEL POPESCU
doaj  

On a Chaotic Weighted Shift zpdp+1/dzp+1 of Order p in Bargmann Space

open access: yesAdvances in Mathematical Physics, 2011
This paper is devoted to the study of the chaotic properties of some specific backward shift unbounded operators Hp=A*pAP+1; p=0,1,… realized as differential operators in Bargmann space, where A and A* are the standard Bose annihilation and creation ...
Abdelkader Intissar
doaj   +1 more source

PERBEDAAN WAKTU REAKSI DAN TINGKAT KELELAHAN ANTARA PEKERJA SHIFT PAGI DAN SHIFT MALAM

open access: yesBerkala Kedokteran, 2015
Fatigue is a feeling of weariness or lack of energy that does not decrease when a person rests. The main reason of occupational accidents caused by humans is stress and fatigue.
Olivia Dewi Rianti   +2 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Les 2x12h : une solution au conflit de temporalités du travail posté ?

open access: yesTemporalités, 2009
Twelve-hour shifts appear to facilitate the flow of temporalities involved in shift work schedules and the different temporal dimensions of human functioning: particularly biological rhythms, private life, and fatigue.
Béatrice Barthe
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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