Results 41 to 50 of about 123,037 (250)

Escherichia coli strains producing a novel Shiga toxin 2 subtype circulate in China.

International Journal of Medical Microbiology, 2019
Shiga toxin (Stx) is the key virulence factor in Shiga toxin producing Escherichia coli (STEC), which can cause diarrhea and hemorrhagic colitis with life-threatening complications. Stx comprises two toxin types, Stx1 and Stx2. Several Stx1/Stx2 subtypes
Xi Yang, X. Bai, Ji Zhang, Hui Sun, Shanshan Fu, Ruyue Fan, Xiaohua He, F. Scheutz, A. Matussek, Y. Xiong   +9 more
semanticscholar   +1 more source

Baicalin Inhibits the Lethality of Shiga-Like Toxin 2 in Mice [PDF]

Antimicrobial Agents and Chemotherapy, 2015
ABSTRACT Shiga-like toxins (Stxs), produced by pathogenic Escherichia coli , are a major virulence factor involved in severe diseases in human and animals. These toxins are ribosome-inactivating proteins, and treatment for diseases caused by them is not available.
Jing, Dong, Yong, Zhang, Yutao, Chen, Xiaodi, Niu, Yu, Zhang, Cheng, Yang, Quan, Wang, Xuemei, Li, Xuming, Deng   +8 more
openaire   +2 more sources

Immunoprophylactic Potential of Cloned Shiga Toxin 2 B Subunit [PDF]

The Journal of Infectious Diseases, 2001
The Shiga toxins Stx1 and Stx2 contribute to the development of enterohemorrhagic O157:H7 Escherichia coli-mediated colitis and hemolytic-uremic syndrome in humans. The Stx2 B subunit, which binds to globotriaosylceramide (GB3) receptors on target cells, was cloned.
P, Marcato, G, Mulvey, R J, Read, , Vander Helm K, P N, Nation, G D, Armstrong   +5 more
openaire   +2 more sources

The A1 Subunit of Shiga Toxin 2 Has Higher Affinity for Ribosomes and Higher Catalytic Activity than the A1 Subunit of Shiga Toxin 1 [PDF]

Infection and Immunity, 2015
ABSTRACT Shiga toxin (Stx)-producing Escherichia coli (STEC) infections can lead to life-threatening complications, including hemorrhagic colitis (HC) and hemolytic-uremic syndrome (HUS), which is the most common cause of acute renal failure in children in the United States.
D. Basu, Xiao-Ping Li, J. N. Kahn, Kerrie L. May, P. Kahn, N. Tumer   +5 more
semanticscholar   +3 more sources

Detection of E. coli O157:H7 and Shigella dysenteriae toxins in clinical samples by PCR-ELISA

Brazilian Journal of Infectious Diseases, 2015
Shiga toxin producing bacteria are potential causes of serious human disease such as hemorrhagic colitis, severe inflammations of ileocolonic regions of gastrointestinal tract, thrombocytopenia, septicemia, malignant disorders in urinary ducts, hemolytic
Jafar Amani, Askary Ahmadpour, Abbas Ali Imani Fooladi, Shahram Nazarian   +3 more
doaj   +1 more source

Virulence profile comparison between LEE-negative Shiga toxin-producing Escherichia coli (STEC) strains isolated from cattle and humans [PDF]

, 2010
For comparison purposes, the prevalence of 8 virulence markers was investigated, by PCR, in 153 cattle and 47 human Locus for Enterocyte Effacement (LEE)-negative Shiga toxin-producing Escherichia coli (STEC) strains isolated in Argentina.
Galli, Lucía, Irino, Kinue, Leotta, Gerardo Anibal, Miliwebsky, Elizabeth, Rivas, Marta   +4 more
core   +1 more source

Cinnamon Oil Inhibits Shiga Toxin Type 2 Phage Induction and Shiga Toxin Type 2 Production in Escherichia coli O157:H7 [PDF]

Applied and Environmental Microbiology, 2016
ABSTRACT This study evaluated the inhibitory effect of cinnamon oil against Escherichia coli O157:H7 Shiga toxin (Stx) production and further explored the underlying mechanisms. The MIC and minimum bactericidal concentration (MBC) of cinnamon oil against E.
Lina, Sheng, Barbara, Rasco, Mei-Jun, Zhu   +2 more
openaire   +2 more sources

C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus

iScience, 2022
Summary: The development of anti-infectives against a large range of AB-like toxin-producing bacteria includes the identification of compounds disrupting toxin transport through both the endolysosomal and retrograde pathways.
Yu Wu, Nassim Mahtal, Eléa Paillares, Léa Swistak, Sara Sagadiev, Mridu Acharya, Caroline Demeret, Sylvie Van Der Werf, Florence Guivel-Benhassine, Olivier Schwartz, Serena Petracchini, Amel Mettouchi, Lucie Caramelle, Pierre Couvineau, Robert Thai, Peggy Barbe, Mathilde Keck, Priscille Brodin, Arnaud Machelart, Valentin Sencio, François Trottein, Martin Sachse, Gaëtan Chicanne, Bernard Payrastre, Florian Ville, Victor Kreis, Michel-Robert Popoff, Ludger Johannes, Jean-Christophe Cintrat, Julien Barbier, Daniel Gillet, Emmanuel Lemichez   +31 more
doaj   +1 more source

Role of Recent Therapeutic Applications and the Infection Strategies of Shiga Toxin-Producing Escherichia coli

Frontiers in Cellular and Infection Microbiology, 2021
Shiga toxin-producing Escherichia coli (STEC) is a global foodborne bacterial pathogen that is often accountable for colon disorder or distress. STEC commonly induces severe diarrhea in hosts but can cause critical illnesses due to the Shiga toxin ...
Su-bin Hwang, Ramachandran Chelliah, Ji Eun Kang, Momna Rubab, Eric Banan-MwineDaliri, Fazle Elahi, Deog-Hwan Oh   +6 more
doaj   +1 more source

Identification and Characterization of a Newly Isolated Shiga Toxin 2-Converting Phage from Shiga Toxin-Producing Escherichia coli [PDF]

Infection and Immunity, 1998
ABSTRACT Shiga toxins 1 (Stx1) and 2 (Stx2) are encoded by toxin-converting bacteriophages of Stx-producing Escherichia coli (STEC), and so far two Stx1- and one Stx2-converting phages have been isolated from two STEC strains (A. D. O’Brien, J. W. Newlands, S. F.
M, Watarai, T, Sato, M, Kobayashi, T, Shimizu, S, Yamasaki, T, Tobe, C, Sasakawa, Y, Takeda   +7 more
openaire   +2 more sources