Results 21 to 30 of about 19,735 (216)

Shiga and Shiga-like toxins [PDF]

open access: yesMicrobiological Reviews, 1987
Introduction . 206 Shiga Toxin in Shigella Spp. . 207 History . 207 Purification and Structure . 207 Mode of Action . 208 Receptor binding and internalization . 208 Inhibition of protein synthesis . 209 Immunology and Immunochemistry . 209 Genetics . 210 Role of Toxin in Disease . 210 Dysentery . 210 Diarrhea .210 HUS . 211 Shiga-like toxins in E. Coli
O'Brien, Alison D., Holmes, Randall K.
openaire   +2 more sources

Comparison of droplet digital PCR and qPCR for the quantification of Shiga toxin-producing Escherichia coli in bovine feces [PDF]

open access: yes, 2016
Cattle are considered to be the main reservoir for Shiga toxin-producing Escherichia coli (STEC) and are often the direct or indirect source of STEC outbreaks in humans.
De Reu, Koen   +5 more
core   +8 more sources

Shiga toxins and apoptosis [PDF]

open access: yesFEMS Microbiology Letters, 2003
The enteric pathogens Shigella dysenteriae serotype 1 and Shiga toxin-producing Escherichia coli (STEC) cause bloody diarrheal diseases that may progress to life-threatening extraintestinal complications. Although the S. dysenteriae and STEC differ in the expression of a number of virulence determinants, they share the capacity to produce one or more ...
Rama P, Cherla   +2 more
openaire   +2 more sources

Shiga Toxin-Producing Escherichia coli: Detection, Differentiation, and Implications for Food Safety

open access: yesEDIS, 2016
Shiga toxin is a protein found within the genome of a type of virus called a bacteriophage. These bacteriophages can integrate into the genomes of the bacterium E. Coli. Even though most E. coli are benign or even beneficial members of our gut microbial
William J. Zaragoza   +2 more
doaj   +5 more sources

Mass Spectrometry-Based Method of Detecting and Distinguishing Type 1 and Type 2 Shiga-Like Toxins in Human Serum

open access: yesToxins, 2015
Shiga-like toxins (verotoxins) are responsible for the virulence associated with a variety of foodborne bacterial pathogens. Direct detection of toxins requires a specific and sensitive technique.
Christopher J. Silva   +4 more
doaj   +1 more source

The pathogenic mechanisms of Shiga toxin and the Shiga‐like toxins [PDF]

open access: yesMolecular Microbiology, 1991
SummaryIt is now well documented that some enteric bacteria which cause diarrhoeal and/or dysenteric disease produce, at high levels, one or more of a family of protein toxins referred to as Shiga toxin and Shiga‐like toxins (SLTs; alternatively called verocytotoxins or VTs).
V L, Tesh, A D, O'Brien
openaire   +2 more sources

Shiga toxin 2-induced intestinal pathology in infant rabbits is A-subunit dependent and responsive to the tyrosine kinase and potential ZAK inhibitor imatinib

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
Shiga toxin producing Escherichia coli (STEC) are a major cause of food-borne illness worldwide. However, a consensus regarding the role Shiga toxins play in the onset of diarrhea and hemorrhagic colitis is lacking.
Samuel eStone   +10 more
doaj   +1 more source

Role of Recent Therapeutic Applications and the Infection Strategies of Shiga Toxin-Producing Escherichia coli

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Shiga toxin-producing Escherichia coli (STEC) is a global foodborne bacterial pathogen that is often accountable for colon disorder or distress. STEC commonly induces severe diarrhea in hosts but can cause critical illnesses due to the Shiga toxin ...
Su-bin Hwang   +6 more
doaj   +1 more source

C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus

open access: yesiScience, 2022
Summary: The development of anti-infectives against a large range of AB-like toxin-producing bacteria includes the identification of compounds disrupting toxin transport through both the endolysosomal and retrograde pathways.
Yu Wu   +31 more
doaj   +1 more source

Virulence profile comparison between LEE-negative Shiga toxin-producing Escherichia coli (STEC) strains isolated from cattle and humans [PDF]

open access: yes, 2010
For comparison purposes, the prevalence of 8 virulence markers was investigated, by PCR, in 153 cattle and 47 human Locus for Enterocyte Effacement (LEE)-negative Shiga toxin-producing Escherichia coli (STEC) strains isolated in Argentina.
Galli, Lucía   +4 more
core   +1 more source

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