Results 111 to 120 of about 24,858 (221)

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel, Manuel J. Verganista, Nuno R. Candeias   +2 more
wiley   +1 more source

New Isozyme Systems for Maize (Zea mays L.): Aconitate Hydratase, Adenylate Kinase, NADH Dehydrogenase, and Shikimate Dehydrogenase [PDF]

, 1988
Electrophoretic variation and inheritance of four novel enzyme systems were studied in maize (Zea mays L.). A minimum of 10 genetic loci collectively encodes isozymes of aconitate hydratase (ACO; EC 4.2.1.3.), adenylate kinase (ADK; EC 2.7.4.3), NADH ...
Beckett, J. B., Goodman, Major, Stuber, Charles, Wendel, Jonathan, Wendel, Jonathan   +4 more
core   +3 more sources

Process development priorities for scaling up direct microbial conversion of sugars into value‐added biochemicals

Biofuels, Bioproducts and Biorefining, Volume 20, Issue 2, Page 747-765, March/April 2026.
Abstract The study identified process development priorities toward the feasible production of five value‐added biochemicals in a sugarcane biorefinery based on achievable bioconversion performances. Multiple process scenarios using A‐molasses as feedstock were simulated in Aspen Plus® via direct microbial conversions.
Manasseh K. Sikazwe, Jeanne Louw, Johann F. Görgens   +2 more
wiley   +1 more source

Functional Characterization of Tea (Camellia sinensis) MYB4a Transcription Factor Using an Integrative Approach

Frontiers in Plant Science, 2017
Green tea (Camellia sinensis, Cs) abundantly produces a diverse array of phenylpropanoid compounds benefiting human health. To date, the regulation of the phenylpropanoid biosynthesis in tea remains to be investigated.
Mingzhuo Li, Yanzhi Li, Lili Guo, Niandi Gong, Yongzheng Pang, Wenbo Jiang, Yajun Liu, Xiaolan Jiang, Lei Zhao, Yunsheng Wang, De-Yu Xie, De-Yu Xie, Liping Gao, Tao Xia   +13 more
doaj   +1 more source

LC‐HESI‐MS/MS Profiling and Evaluation of Antioxidant, Anti‐Inflammatory, Anti‐α‐Amylase, and Anti‐Acetylcholinesterase Activities of Rhus tripartitum L. Leaf Extract: In Vitro and In Silico Studies

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
ABSTRACT This study aims to assess the biological characteristics of Rhus tripartitum leaves and identify their promising biomolecules. The numerous extracts of R. tripartitum leaves were evaluated, in vitro, for their phytochemical profile and antioxidant, anti‐acetylcholinesterase, α‐amylase, and anti‐inflammatory activities. The methanolic and ethyl
Raoudha Ben Ameur, Imen Rekik, Nourhène Hamdaoui, Siwar Soltani, Nathan Téné, Michel Treilhou, Mongi Saoudi, Noureddine Allouche   +7 more
wiley   +1 more source

Gallic Acid: A Potent Metabolite Targeting Shikimate Kinase in Acinetobacter baumannii

Metabolites
Background/Objectives: Acinetobacter baumannii is a highly multidrug-resistant pathogen resistant to almost all classes of antibiotics; new therapeutic strategies against this infectious agent are urgently needed.
Mansour S. Alturki, Abdulaziz H. Al Khzem, Mohamed S. Gomaa, Nada Tawfeeq, Marwah H. Alhamadah, Futun M. Alshehri, Raghad Alzahrani, Hanin Alghamdi, Thankhoe A. Rants’o, Khaled A. G. Ayil, Abdulaziz K. Al Mouslem, Mohammed Almaghrabi   +11 more
doaj   +1 more source

Assessment of Metabolites in Noni Fruit Slurry Fermented With Four Non‐Saccharomyces Yeasts

Food Frontiers, Volume 7, Issue 2, March 2026.
Dried noni fruit slurry (DNFS) was fermented for 14 days with selected non‐Saccharomyces yeasts. GCMS, HPLC and amino acid analysis showed that Pichia kluyveri Frootzen and Williopsis saturnus NCYC22 grew well, reduced off‐flavor fatty acids, generated fruity aroma compounds and preserved total phenolic content. ABSTRACT Noni products often suffer from
Zhuoran Zhang, Shao Quan Liu, Yuyun Lu
wiley   +1 more source

Shikimate Dehydrogenase Structure Reveals Novel Fold [PDF]

Structure, 2003
The structure of shikimate 5-dehydrogenase, the fourth enzyme in the shikimate biosynthesis pathway and a member of a large enzyme family without clear structural peer, reveals a novel topological fold for the substrate binding domain and, through homology modeling, expands the possibilities for antimicrobial and herbicide design.
openaire   +2 more sources

The arogenate dehydratase ADT2 is essential for seed development in Arabidopsis [PDF]

, 2018
Phenylalanine (Phe) biosynthesis in plants is a key process, as Phe serves as precursor of proteins and phenylpropanoids. The prephenate pathway connects chorismate, final product of the shikimate pathway, with the biosynthesis of Phe and Tyr.
Canovas-Ramos, Francisco Miguel, De la Torre, Fernando, El-Azaz Ciudad, Jorge, Ávila, Concepción   +3 more
core  

A Pathway‐Based Metabolomics Approach Reveals Metabolic Strategies and Reprogramming in Drought‐Tolerant Soybean Genotypes

Legume Science, Volume 8, Issue 1, March 2026.
ABSTRACT Soybean (Glycine max) is a globally important crop, yet its productivity is highly susceptible to drought stress, particularly in rainfed systems. To better understand the biochemical basis of drought tolerance, this study employed pathway‐based metabolomics to characterize differentially expressed metabolites between drought‐tolerant and ...
Namhee Lee, Donna K. Harris, Zenglu Li, Joon Hyuk Suh   +3 more
wiley   +1 more source