Results 131 to 140 of about 5,044 (156)

Discovery of Helicobacter pylori shikimate kinase inhibitors: Bioassay and molecular modeling

Bioorganic & Medicinal Chemistry, 2007
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway and catalyzes the phosphate transfer from ATP to shikimate in generating shikimate 3-phosphate and ADP. SK has been developed as a promising target for the discovery of antibacterial agents.
Cong, Han, Jian, Zhang, Lili, Chen, Kaixian, Chen, Xu, Shen, Hualiang, Jiang   +5 more
openaire   +2 more sources

Structure of shikimate kinase, anin vivoessential metabolic enzyme in the nosocomial pathogenAcinetobacter baumannii, in complex with shikimate

Acta Crystallographica Section D Biological Crystallography, 2015
Acinetobacter baumanniiis an opportunistic Gram-negative pathogen that is an important cause of healthcare-associated infections exhibiting high mortality rates. Clinical isolates of multidrug-resistant (MDR) and extremely drug-resistant (XDR)A. baumanniistrains are increasingly being observed.
Kristin A, Sutton, Jennifer, Breen, Ulrike, MacDonald, Janet M, Beanan, Ruth, Olson, Thomas A, Russo, L Wayne, Schultz, Timothy C, Umland   +7 more
openaire   +2 more sources

Nucleotide sequence of the shikimate kinase gene (aroI) of Bacillus subtilis

Journal of Fermentation and Bioengineering, 1994
Abstract Shikimate kinase is an enzyme in the pathway of aromatic amino acid biosynthesis. The gene for this enzyme of Bacillus subtilis, aroI , was cloned and its nucleotide sequence determined. The gene consists of 186 amino acid codons. The enzyme shares 40.4% and 26.2% amino acid identity with Escherichia coli shikimate kinase I (AroK) and II (
Akitaka Nakane, Kou-Ichiro Ogawa, Kouji Nakamura, Kunio Yamane   +3 more
openaire   +1 more source

Mechanistic studies on chorismate synthase and shikimate kinase

1994
This thesis was digitised by the British Library from microfilm. You can acquire a single copy of this thesis for research purposes by clicking on the padlock icon on the thesis file. Please be aware that the text in the supplied thesis pdf file may not be as clear as text in a thesis that was born digital or digitised directly from paper due to the ...
openaire   +1 more source

Shikimate kinase

1997
Dietmar Schomburg, Dörte Stephan
openaire   +1 more source

Shikimate Kinase Inhibitors: An Update on Promising Strategy against Mycobacterium tuberculosis

Current Drug Targets, 2023
Ashish Runthala, Inshad Khan
exaly  

Identification of novel scaffold using ligand and structure based approach targeting shikimate kinase

Bioorganic Chemistry, 2020
M K Kathiravan, M K Kathiravan
exaly  

The three-dimensional structure of shikimate kinase 1 1Edited by K. Nagai

Journal of Molecular Biology, 1998
Tino Krell, John R Coggins, A J Lapthorn   +2 more
exaly  

Structure of shikimate kinase fromMycobacterium tuberculosisreveals the binding of shikimic acid

Acta Crystallographica Section D: Biological Crystallography, 2004
Fernanda Canduri, Walter F DE AZEVEDO, Marcio Dias   +2 more
exaly  

Shikimate kinase

2007
openaire   +1 more source