BioChemMetabolic engineering of the shikimate pathway offers a promising strategy for enhancing the production of aromatic compounds in microbial hosts. However, feedback inhibition of key enzymes, such as the 3-deoxy-D-arabino-heptulosonate 7-phosphate ...
William Merre +4 more
doaj +1 more source
An Evolutionary Conservation and Druggability Analysis of Enzymes Belonging to the Bacterial Shikimate Pathway. [PDF]
Antibiotics (Basel), 2022 Frlan R.
europepmc +1 more source
The effect of an elevated atmospheric CO(_2) concentration on secondary metabolism and resource allocation in plantago maritima and armeria maritima [PDF]
, 2003 There are relatively few reports concerning carbon and nitrogen partitioning into secondary metabolism in plants grown in elevated atmospheric CO(_2). This thesis investigates the effects of changes in atmospheric CO(_2) and soil nitrogen availability ...
Davey, Matthew Paul
core
Shikimate Dehydrogenase Structure Reveals Novel Fold
, 2003 The structure of shikimate 5-dehydrogenase, the fourth enzyme in the shikimate biosynthesis pathway and a member of a large enzyme family without clear structural peer, reveals a novel topological fold for the substrate binding domain and, through ...
Vogan, Erik
core +1 more source
Structural basis for shikimate-binding specificity of Helicobacter pylori shikimate kinase
, 2010 [[abstract]]Shikimate kinase (EC 2.7.1.71) catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid in the presence of ATP. As the fifth key step in the shikimate pathway for aromatic amino acid biosynthesis in bacteria, fungi, and
Cheng WC;Chang YN;Wang WC
core +2 more sources
The Levels of DAHP Synthase, the First Enzyme of the Shikimate Pathway, Are Related to Free Aromatic Amino Acids and Glutamine Content in Nicotiana plumbaginifolia Cell Cultures. [PDF]
Plants (Basel), 2023 Forlani G, Giberti S, Doria E.
europepmc +1 more source
Novel exported fusion enzymes with chorismate mutase and cyclohexadienyl dehydratase activity: Shikimate pathway enzymes teamed up in no man's land. [PDF]
J Biol Chem, 2023 Stocker C +6 more
europepmc +1 more source
Hybrid Chemoenzymatic Synthesis of C7 -Sugars for Molecular Evidence of in vivo Shikimate Pathway Inhibition. [PDF]
Chembiochem, 2022 Rath P +6 more
europepmc +1 more source
The entry reaction of the plant shikimate pathway is subjected to highly complex metabolite-mediated regulation. [PDF]
Plant Cell, 2021 Yokoyama R +3 more
europepmc +1 more source
Computational Insights and In Vitro Validation of Antibacterial Potential of Shikimate Pathway-Derived Phenolic Acids as NorA Efflux Pump Inhibitors. [PDF]
Molecules, 2022 Singh K +3 more
europepmc +1 more source