Computational investigation of African natural products as Helicobacter pylori shikimate kinase inhibitors. [PDF]
Sharma Paudel HR.
europepmc +1 more source
Systems engineering of <i>Escherichia coli</i> for high-level hydroxytyrosol production. [PDF]
Zuo J +12 more
europepmc +1 more source
Methanol-based biosynthesis of p-coumaric acid by engineered Pichia pastoris. [PDF]
Chen M +7 more
europepmc +1 more source
Heterologous expression of hydroxylase coupled with pathway optimization enables highly efficient ʟ-DOPA production in <i>Corynebacterium glutamicum</i>. [PDF]
Jia M +7 more
europepmc +1 more source
High-yield production of hydroxytyrosol through metabolic engineering of <i>Yarrowia lipolytica</i>. [PDF]
Chen B +6 more
europepmc +1 more source
Integrated metabolomic, proteomic, and transcriptomic analyses reveal the production of bioactive metabolites and antidiabetic effects in mature <i>Solanum lasiocarpum</i> fruit. [PDF]
Li F +13 more
europepmc +1 more source
Cadmium stress triggers dopamine signaling in duckweed (<i>Lemna turionifera</i> 5511) revealed by a fluorescent biosensor. [PDF]
Hao B +6 more
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The shikimate pathway regulates programmed cell death
Journal of Genetics and Genomics, 2022Programmed cell death (PCD) is essential for both plant development and stress responses including immunity. However, how plants control PCD is not well-understood. The shikimate pathway is one of the most important metabolic pathways in plants, but its relationship to PCD is unknown. Here, we show that the shikimate pathway promotes PCD in Arabidopsis.
Xueao Zheng +2 more
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▪ Abstract The shikimate pathway links metabolism of carbohydrates to biosynthesis of aromatic compounds. In a sequence of seven metabolic steps, phosphoenolpyruvate and erythrose 4-phosphate are converted to chorismate, the precursor of the aromatic amino acids and many aromatic secondary metabolites.
Klaus M., Herrmann, Lisa M., Weaver
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Creation of a Shikimate Pathway Variant
Journal of the American Chemical Society, 2004The competition between the Escherichia coli carbohydrate phosphotransferase system and 3-deoxy-d-arabino-heptulosonate 7-phosphate (DAHP) synthase for phosphoenolpyruvate limits the concentration and yield of natural products microbially synthesized via the shikimate pathway.
Ningqing, Ran, K M, Draths, J W, Frost
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