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Creation of a Shikimate Pathway Variant
Journal of the American Chemical Society, 2004The competition between the Escherichia coli carbohydrate phosphotransferase system and 3-deoxy-d-arabino-heptulosonate 7-phosphate (DAHP) synthase for phosphoenolpyruvate limits the concentration and yield of natural products microbially synthesized via the shikimate pathway.
Ningqing, Ran, K M, Draths, J W, Frost
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The shikimate pathway regulates programmed cell death
Journal of Genetics and Genomics, 2022Programmed cell death (PCD) is essential for both plant development and stress responses including immunity. However, how plants control PCD is not well-understood. The shikimate pathway is one of the most important metabolic pathways in plants, but its relationship to PCD is unknown. Here, we show that the shikimate pathway promotes PCD in Arabidopsis.
Xuerui, Lu +6 more
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A complete shikimate pathway in Toxoplasma gondii: an ancient eukaryotic innovation
International Journal for Parasitology, 2004 The shikimate pathway is essential for survival of the apicomplexan parasites Plasmodium falciparum, Toxoplasma gondii and Cryptosporidium parvum. As it is absent in mammals it is a promising therapeutic target. Herein, we describe the genes encoding the
Thomas A Richards +2 more
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2014
Of the identified biosynthetic paths, shikimic acid pathway plays a very important role in providing precursors of a large number of aromatic compounds of diverse skeletal patterns and substitutions. Chorismic acid, an important branching point product in the shikimic acid pathway also serves as an important precursor. Natural products with C 6 –C 1 or
Sunil Kumar Talapatra, Bani Talapatra
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Of the identified biosynthetic paths, shikimic acid pathway plays a very important role in providing precursors of a large number of aromatic compounds of diverse skeletal patterns and substitutions. Chorismic acid, an important branching point product in the shikimic acid pathway also serves as an important precursor. Natural products with C 6 –C 1 or
Sunil Kumar Talapatra, Bani Talapatra
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Dynamics of the shikimate pathway in plants
Trends in Plant Science, 1997The shikimate pathway, a collection of seven enzymatic reactions whose end product is chorismate, has been studied for many years in a variety of microorganisms and plants. In microbial systems, the end product of the pathway is used primarily for the synthesis of aromatic amino acids.
Lisa M. Weaver, Klaus M. Herrmann
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Shikimic Acid Pathway: Phenols
2023Plant metabolites having one or more hydroxyl groups attached to an aromatic ring are known as phenols. Phenols are a heterogeneous group of compounds. One of the most important functions of phenols is in plant communication e.g., allelopathy, attracting pollinating and disseminating agents, attracting symbiotic bacteria, and inhibiting pathogens and ...
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1979
The shikimate pathway is the major metabolic route leading to the formation of aromatic compounds in living systems. It operates in microorganisms and in higher plants, but not in animals, which is why the latter are dependent on a dietary supply of the aromatic amino acids phenylalanine, tyrosine and tryptophan.
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The shikimate pathway is the major metabolic route leading to the formation of aromatic compounds in living systems. It operates in microorganisms and in higher plants, but not in animals, which is why the latter are dependent on a dietary supply of the aromatic amino acids phenylalanine, tyrosine and tryptophan.
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Shikimic Acid Pathway Metabolites
1981Benzenoid compounds in plants are biosynthesised by two main pathways: the shikimic acid pathway and the acetate-malonate pathway (Chapter 4). In higher plants, a large number of aromatic compounds are derived from phenylalanine, tyrosine and tryptophan, end-products of the shikimic acid pathway.
Margaret L. Vickery, Brian Vickery
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The Shikimate Pathway — A Metabolic Tree with Many Branche
Critical Reviews in Biochemistry and Molecular Biology, 1990(1990). The Shikimate Pathway — A Metabolic Tree with Many Branche. Critical Reviews in Biochemistry and Molecular Biology: Vol. 25, No. 5, pp. 307-384.
Ronald Bentley, E. Haslam
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Fluorine-containing analogs of intermediates in the shikimate pathway
Biochemistry, 1976The phosphoenolpyruvate analogue (Z)-phosphoenol-3-fluoropyruvate is a substrate for phenylalanine-inhibitable 3-deoxy-D-arabino-heptulosonic acid-7-phosphate synthase from Escherichia coli. In the presence of excess erythrose 4-phosphate, apparent KM values of 65 and 38 muM were observed for phosphoenol-3-fluoropyruvate and phosphoenolpyruvate ...
P F, Pilch, R L, Somerville
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