Results 181 to 190 of about 1,097,275 (327)

Carotid Doppler and IVC metrics for volume and mortality assessment in septic shock. [PDF]

Libyan J Med
Kaymakçı R, Arslan V, Aksan A, Karaca MA.   +3 more
europepmc   +1 more source

CRISPR in MOF Formulation with Enhanced Stability, Activity, and Altered PAM Specificity for Broad‐Spectrum Diagnosis of Bacterial Sepsis

Advanced Science, EarlyView.
CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal, Zilong Liu, Meera G. Nair, Juhong Chen   +3 more
wiley   +1 more source

Sepsis and septic shock case identification from electronic health records: an open-source workflow and comparison of cohorts by criteria. [PDF]

Crit Care
Bauer SR, Mourany L, Gunsalus PR, Milinovich A, Kane-Gill SL, Wang X, Tarabichi Y, Vachharajani V, Dalton JE.   +8 more
europepmc   +1 more source

Fever Inspiration: Precision Engineering for Safe and Systemic Immunotherapy

Advanced Science, EarlyView.
This review examines engineered fever therapy (EFT) as a novel cancer treatment, harnessing fever's immunomodulatory effects to enhance systemic immune responses. It explores molecular mechanisms, advances in nanotechnology‐driven thermal immunotherapy, and a bioengineered framework for precise, safe fever induction. The paper evaluates EFT's potential
Yang Li, Fulong Man, Jianwei Cheng, Li Chen, Yongyong Li, Haiqing Dong   +5 more
wiley   +1 more source

Factors associated with mortality in pediatric septic shock in Thai children with long-term survival analysis post-hospital discharge: a nationwide study 2015-2022. [PDF]

Sci Rep
Uppala R, Sitthikarnkha P, Niamsanit S, Techasatian L, Saengnipanthkul S, Thepsuthammarat K, Kosalaraksa P.   +6 more
europepmc   +1 more source

Pathomechanismus in Septic Shock [PDF]

, 1986
Duswald, Karl-Heimo, Eitel, F., Fritz, Hans, Inthorn, D., Jochum, Marianne, Schweiberer, L.   +5 more
core  

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Restrictive Versus Standard Intravenous Fluid Therapy and Endothelial Glycocalyx Shedding in ICU Patients With Septic Shock-A Preplanned Sub-Study of the Randomized CLASSIC Trial. [PDF]

Acta Anaesthesiol Scand
Christensen J, Sivapalan P, Meyhoff TS, Järnbert-Pettersson H, Perner A, Møller MH, Lange T, Hjortrup PB, Joelsson-Alm E, Jonmarker S, Sjöberg F, Mårtensson J, Gladh AH, Cronhjort M.   +13 more
europepmc   +1 more source

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

Advanced Science, EarlyView.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang, Qi Gao, Yi Peng, Huan Zhang, Qi Shen, Meihong Guo, Yuqing Gong, Lei Chu, Weidong Wu, Yanting Wen, Wangsen Cao, Yong Wang, Lihui Wang   +12 more
wiley   +1 more source

Current and emerging therapeutic options for refractory septic shock: A systematic review. [PDF]

World J Crit Care Med
Nacul FE, Bezerra MB, Gomes BC, Hohmann FB, Treml RE, Caldonazo T, da Silva AA, Passos RH, de Oliveira NE, Bedretchuk GP, Silva JM.   +10 more
europepmc   +1 more source