Objective To evaluate the applicability of the 2016 EULAR/ACR/PRINTO macrophage activation syndrome (MAS) classification criteria in patients with Still's disease (sJIA‐SD) treated with IL‐1‐targeted therapy and to assess the incidence of MAS in this context.
Remco G.A. Erkens+14 more
wiley +1 more source
Reversible Myocardial Depression and Dilatation in COVID-19 Shock Patients. [PDF]
Fata MJ+7 more
europepmc +1 more source
Autoantibody response towards chromatin in patients with juvenile idiopathic arthritis
Objective Juvenile idiopathic arthritis (JIA) patients frequently exhibit antinuclear antibodies (ANAs), but the specific antigen target recognized by them and the presence of additional autoantibody specificities in JIA patients remains elusive. Methods Plasma samples from 110 untreated patients with active JIA, as well as from 14 children with ...
Viola Pitkänen+13 more
wiley +1 more source
Medications, epilepsy and climate change: Added layers of complexity
Climate change—the global crisis with pervasive health impacts—has adverse consequences for people with epilepsy (PWE) who have low quality of life due to poor seizure control, socioeconomic disadvantages and comorbidities. This review focuses on the potential effects of climate change on the pharmacological characteristics of antiseizure medications ...
Medine I. Gulcebi+2 more
wiley +1 more source
The clinical significance of thrombocytopenia in sepsis and septic shock: a systematic review and meta-analysis. [PDF]
Alqeeq BF+6 more
europepmc +1 more source
Diagnostic and Predictive Values of Soluble Triggering Receptor Expressed on Myeloid Cells-1 in Sepsis: A Multi-Center Prospective Clinical Study. [PDF]
Wang K+12 more
europepmc +1 more source
Restoration of human tooth enamel
Human tooth enamel has remarkable properties but lacks self‐repair ability. Existing restorative materials cannot fully replicate enamel's microstructure and function, resulting in low restorative efficiency. This review summarizes the formation process and characteristics of enamel, and current restorative materials and future research directions are ...
Hanlin Liu+10 more
wiley +1 more source
The value of NT-proBNP, NLR, Ang-1 combined with APACHE II and SOFA scores in evaluating 28-day mortality of septic shock. [PDF]
Peng L+5 more
europepmc +1 more source
Abstract Plasma expanders (PEs) are commonly used to replace lost blood volume for septic shock patients with increased vascular permeability. Human serum albumin (HSA) is the preferred PE, due to its innate ability to restore blood colloid osmotic pressure (COP).
Amna Abdalbaqi+7 more
wiley +1 more source
Efficacy and safety of corticosteroids in critically ill patients: a systematic review and meta-analysis. [PDF]
Cao L+6 more
europepmc +1 more source