Results 21 to 30 of about 213,649 (301)

Proenkephalin A 119-159 (Penkid) Is an Early Biomarker of Septic Acute Kidney Injury: The Kidney in Sepsis and Septic Shock (Kid-SSS) Study [PDF]

, 2018
Introduction: Sepsis is the leading cause of acute kidney injury (AKI) in critically ill patients. The Kidney in Sepsis and Septic Shock (Kid-SSS) study evaluated the value of proenkephalin A 119-159 (penkid)—a sensitive biomarker of glomerular function,
Antonelli, M., Beishuizen, A., Bergmann, A., Chousterman, B. G., Constatin, J. -M., Damoisel, C., Deye, N., Di Somma, S., Dugernier, T., Francois, B., Gaudry, S., Gayat, E., Hartmann, O., Hollinger, A., Huberlant, V., Lascarrou, J. -B., Laterre, P. -F., Legrand, M., Marx, G., Mebazaa, A., Mercier, E., Oueslati, H., Pickkers, P., Sonneville, R., Struck, J., Wittebole, X.   +25 more
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Effect of stress doses of hydrocortisone on S-100B vs. interleukin-8 and polymorphonuclear elastase levels in human septic shock [PDF]

, 2005
Stress doses of hydrocortisone a re known to have immunomodulatory effects in patients with hyperdynamic septic shock. The prognosis correlates with the presence and severity of septic encephalopathy. However, neurological evaluation is influenced by the
Anderson, Annane, Astudillo, Barie, Barie, Bastos, Bertsch, Blomquist, Bollaert, Bolton, Bolton, Bone, Briegel, Briegel, Briegel, Briegel, Danielson, Donato, Eidelman, Endo, Haimoto, Herrmann, Hollenberg, Hund, Hund, Jonsson, Keh, Lindner, Marshall, Metinko, Munck, Mussack, Mussack, Pelinka, Pelinka, Rosen, Schwarz, Stanimirovic, Usui, Vincent, Waage, Weiss, Westaby, Wheeler, Wiesmann, Wunderlich, Young   +46 more
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The Role of Complement System in Septic Shock

Clinical and Developmental Immunology, 2012
Septic shock is a critical clinical condition with a high mortality rate. A better understanding of the underlying mechanisms is important to develop effective therapies.
Jean Charchaflieh, Jiandong Wei, Georges Labaze, Yunfang Joan Hou, Benjamin Babarsh, Helen Stutz, Haekyung Lee, Samrat Worah, Ming Zhang   +8 more
doaj   +1 more source

Fluid balance and cardiac function in septic shock as predictors of hospital mortality [PDF]

, 2013
INTRODUCTION: Septic shock is a major cause of morbidity and mortality throughout the world. Unfortunately, the optimal fluid management of septic shock is unknown and currently is empirical.
Doherty, Joshua A, Hampton, Nicholas, Kollef, Marin H, McEvoy, Colleen, McKenzie, Matthew, Micek, Scott T   +5 more
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Changes in Circulating Procalcitonin Versus C-Reactive Protein in Predicting Evolution of Infectious Disease in Febrile, Critically Ill Patients [PDF]

, 2013
Objective:Although absolute values for C-reactive protein (CRP) and procalcitonin (PCT) are well known to predict sepsis in the critically ill, it remains unclear how changes in CRP and PCT compare in predicting evolution of: infectious disease ...
Groeneveld, A.B.J. (Johan), Hoeboer, S.H. (Sandra)   +1 more
core   +10 more sources

Risk factors and outcomes for ineffective empiric treatment of sepsis caused by gram-negative pathogens: Stratification by onset of infection [PDF]

, 2017
Sepsis and septic shock remain serious consequences of infections, with reported mortality rates in excess of 40 percent. Timely antibiotic therapy in cases of sepsis and septic shock is recognized as an important determinant of outcome.
Hampton, Nicholas, Kollef, Marin, Micek, Scott T   +2 more
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Characteristics and Outcomes of Patients with Vasoplegic Versus Tissue Dysoxic Septic Shock [PDF]

, 2013
Background: The current consensus definition of septic shock requires hypotension after adequate fluid challenge or vasopressor requirement. Some patients with septic shock present with hypotension and hyperlactatemia greater than 2 mmol/L (tissue ...
Jones, Alan E, Kline, Jeffrey A., Puskarich, Michael A, Shapiro, Nathan I, Sterling, Sarah A, Summers, Richard L, Trzeciak, Stephen   +6 more
core   +1 more source

Is there NO treatment for severe sepsis? [PDF]

, 2008
Sepsis is a systemic inflammatory response syndrome in the presence of suspected or proven infection, and it may progress to or encompass organ failure (severe sepsis) and hypotension (septic shock).
Bredan, Amin, Cauwels, Anje
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Characteristics of Sepsis-2 septic shock patients failing to satisfy the Sepsis-3 septic shock definition: an analysis of real-time collected data

Annals of Intensive Care, 2021
Background Baseline characteristics and disease severity of patients with septic shock according to the new Sepsis-3 definition may differ from patients that only comply with the Sepsis-2 definition.
Joris Vermassen, Johan Decruyenaere, Liesbet De Bus, Pieter Depuydt, Kirsten Colpaert   +4 more
doaj   +1 more source

Terlipressin or norepinephrine in septic shock: do we have the answer? [PDF]

, 2019
Comment on Terlipressin versus norepinephrine as infusion in patients with septic shock: a multicentre, randomised, double-blinded trial.
Russell, James A., Williams, Mark D.
core   +1 more source