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Septic Shock

Veterinary Clinics of North America: Small Animal Practice, 1989
Septic shock is a life-threatening condition that results from the combined effects of bacteria and the host's chemical mediators of inflammation. Of particular detriment is the hyperdynamic and hypodynamic vasomotor instability that severely compromises the patient prior to the onset of overt bacteremia.
Resident, From the Department of Small Animal Clinical Sciences, University of Florida College of Veterinary Medicine, Gainesville, Florida ( host institution ), Goodwin, John-Karl ( author ), Schaer, Michael ( author )   +2 more
openaire   +5 more sources

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

Intensive Care Medicine, 2013
ObjectiveTo provide an update to the “Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock,” last published in 2008.DesignA consensus committee of 68 international experts representing 30 international organizations was ...
R. Dellinger, M. Levy, A. Rhodes, D. Annane, H. Gerlach, S. Opal, J. Sevransky, C. Sprung, I. Douglas, R. Jaeschke, T. Osborn, M. Nunnally, S. Townsend, K. Reinhart, R. Kleinpell, D. Angus, C. Deutschman, F. Machado, G. Rubenfeld, S. Webb, R. Beale, J. Vincent, R. Moreno, The Surviving Sepsis Campaign Guidelines Committee inc Subgroup   +23 more
semanticscholar   +1 more source

Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children

Pediatric Critical Care Medicine, 2020
Supplemental Digital Content is available in the text. Objectives: To develop evidence-based recommendations for clinicians caring for children (including infants, school-aged children, and adolescents) with septic shock and other sepsis-associated organ
S. Weiss, M. Peters, W. Alhazzani, M. Agus, H. Flori, D. Inwald, S. Nadel, L. Schlapbach, R. Tasker, A. Argent, J. Brierley, J. Carcillo, E. Carrol, C. Carroll, I. Cheifetz, K. Choong, Jeffry J. Cies, A. Cruz, D. De Luca, A. Deep, S. Faust, C. F. de Oliveira, M. Hall, P. Ishimine, E. Javouhey, K. Joosten, P. Joshi, O. Karam, M. Kneyber, J. Lemson, G. MacLaren, N. Mehta, M. Møller, C. Newth, Trung C. Nguyen, A. Nishisaki, M. Nunnally, M. Parker, Raina M. Paul, A. Randolph, S. Ranjit, L. Romer, Halden F. Scott, L. Tume, J. Verger, E. Williams, J. Wolf, H. Wong, J. Zimmerman, N. Kissoon, P. Tissières   +50 more
semanticscholar   +1 more source

Endothelial damage in septic shock patients as evidenced by circulating syndecan-1, sphingosine-1-phosphate and soluble VE-cadherin: a substudy of ALBIOS

Critical Care, 2021
Background Septic shock is characterized by breakdown of the endothelial glycocalyx and endothelial damage, contributing to fluid extravasation, organ failure and death. Albumin has shown benefit in septic shock patients.
Arianna Piotti, D. Novelli, J. Meessen, D. Ferlicca, Sara Coppolecchia, A. Marino, G. Salati, M. Savioli, G. Grasselli, G. Bellani, A. Pesenti, S. Masson, P. Caironi, L. Gattinoni, M. Gobbi, C. Fracasso, R. Latini, Paola Francesca Riccarda Andrea Chiara Beatrice Stefano Bruzzone Pagan Russo Confalonieri Abbruzzese Vergn, P. Bruzzone, F. Pagan, R. Russo, A. Confalonieri, C. Abbruzzese, B. Vergnano, S. Faenza, A. Siniscalchi, E. Pierucci, A. Noto, A. Pezzi, P. Spanu, V. Parrini, R. Oggioni, G. Pasetti, M. Casadio, Rosa Buontempo, S. Carrer, F. Piccoli, Tatiana Rizzi, A. Caricato, M. La Sala, A. Antonaci, P. Fassini, Silvia Paganini, V. Porta, G. Moise, Silvia Marell, M. Furia, Maria Cristina Urbano, Roberta Carobbi, Simona Poleni, H. Kandil, A. Ballotta, F. Bettini, M. Sanseverino, A. Gatta, F. Cecchini, Luca Guatteri, G. Ciceri, F. Raimondi, Roberto Colombo, S. Ferraris, Massimo Borelli, V. Bellato, Franco Cancellieri, Silvia Senni, Ester Bertocchi, P. Ferri, Gianpietro Moioli, A. Fedele, A. Molin, G. Salati, P. Salsi, E. Brunori, D. Elisei, Giuseppe Maggio, F. Nicola, M. Cavana, G. Morelli, A. Guarino, Michele Isetta, G. Tulli, V. Mangani, N. Rossi, Marta Ferrari, F. Bona, Monica Vay, Teresa M. Bartoli, Mauro Gallo, K. Vettoretto, M. D. Morte, E. Boselli, D. Puscio, Monia Bovo, A. Galzerano, Manuela Carli, G. Zagara   +95 more
semanticscholar   +1 more source

Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008

Intensive Care Medicine, 2007
ObjectiveTo provide an update to the original Surviving Sepsis Campaign clinical management guidelines, “Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock,” published in 2004.DesignModified Delphi method with a ...
R. Dellinger, Mitchell M. Levy, J. Carlet, Julian Bion, Margaret M. Parker, R. Jaeschke, K. Reinhart, D. Angus, C. Brun-Buisson, Richard J. Beale, Thierry Calandra, Jean-François Dhainaut, H. Gerlach, Maurene Harvey, John J. Marini, John C. Marshall, Marco Ranieri, Graham Ramsay, J. Sevransky, B. T. Thompson, S. Townsend, J. Vender, Janice L. Zimmerman, J. Vincent   +23 more
semanticscholar   +1 more source

Mortality in sepsis and septic shock in Europe, North America and Australia between 2009 and 2019— results from a systematic review and meta-analysis

Critical Care, 2020
Background Sepsis and septic shock remain drivers for mortality in critically ill patients. The heterogeneity of the syndrome hinders the generation of reproducible numbers on mortality risks. Consequently, mortality rates range from 15 to 56%.
M. Bauer, H. Gerlach, T. Vogelmann, F. Preissing, J. Stiefel, D. Adam   +5 more
semanticscholar   +1 more source

Impact of Empirical Antibiotic Regimens on Mortality in Neutropenic Patients with Bloodstream Infection Presenting with Septic Shock

Antimicrobial Agents and Chemotherapy, 2021
We analyzed risk factors for mortality in febrile neutropenic patients with bloodstream infections (BSI) presenting with septic shock and assessed the impact of empirical antibiotic regimens.
Mariana Chumbita, P. Puerta-Alcalde, C. Gudiol, Nicole García-Poutón, J. Laporte-Amargós, A. Ladino, A. Albasanz-Puig, Cristina Helguera, A. Bergas, I. Grafia, E. Sastre, M. Suárez-Lledó, X. Durà, Carl Jordan, F. Marco, M. Condom, P. Castro, J. Martinez, J. Mensa, Á. Soriano, J. Carratalá, C. García-Vidal   +21 more
semanticscholar   +1 more source

An overview of the mechanisms and potential roles of extracellular vesicles in septic shock

Frontiers in Immunology
Septic shock, a subset of sepsis, is a fatal condition associated with high morbidity and mortality. However, the pathophysiology of septic shock is not fully understood. Moreover, the diagnostic markers employed for identifying septic shock lack optimal
Meiling Cao, Mingyue Shi, Boru Zhou, Hongkun Jiang   +3 more
doaj   +1 more source

CD63 and C3AR1: The Potential Molecular Targets in the Progression of Septic Shock

International Journal of General Medicine, 2022
Ning Yu, Xuefang Liu, Dandan Shi, Long Bai, Tianfu Niu, Ya Liu Department of Anaesthesiology and Intensive Care, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, 050004, People’s Republic of ChinaCorrespondence: Ya Liu,
Yu N, Liu X, Shi D, Bai L, Niu T, Liu Y
doaj  

Bioinformatic analysis identifies potential biomarkers and therapeutic targets of septic-shock-associated acute kidney injury

Hereditas, 2021
Background Sepsis and septic shock are life-threatening diseases with high mortality rate in intensive care unit (ICU). Acute kidney injury (AKI) is a common complication of sepsis, and its occurrence is a poor prognostic sign to septic patients.
Yun Tang, Xiaobo Yang, Huaqing Shu, Yuan Yu, Shangwen Pan, Jiqian Xu, You Shang   +6 more
doaj   +1 more source