Results 41 to 50 of about 1,097,275 (327)

Tricuspid Annular Plane of Systolic Excursion for the Evaluation of Patients with Severe Sepsis and Septic Shock [PDF]

, 2020
Introduction: Sepsis is a systemic infection that can rapidly progress into multi organ failure and shock if left untreated. Previous studies have demonstrated the utility of point of care ultrasound (POCUS) in the evaluation of patients with sepsis ...
Ali, Qumber, Fischetti, Chanel, Fox, John C., Lahham, Shadi, Lee, Clifton, Moeller, John, Saadat, Soheil, Thompson, Maxwell   +7 more
core  

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2020
Importance It is unclear whether vitamin C, hydrocortisone, and thiamine are more effective than hydrocortisone alone in expediting resolution of septic shock.
T. Fujii, N. Luethi, P. Young, D. Frei, G. Eastwood, C. French, A. Deane, Y. Shehabi, L. Hajjar, G. Oliveira, A. Udy, N. Orford, S. Edney, A. Hunt, H. Judd, L. Bitker, L. Cioccari, T. Naorungroj, Fumitaka Yanase, S. Bates, F. McGain, Elizabeth P Hudson, W. Al-Bassam, D. B. Dwivedi, C. Peppin, P. Mccracken, J. Orosz, M. Bailey, R. Bellomo   +28 more
semanticscholar   +1 more source

Impact of Empirical Antibiotic Regimens on Mortality in Neutropenic Patients with Bloodstream Infection Presenting with Septic Shock

Antimicrobial Agents and Chemotherapy, 2021
We analyzed risk factors for mortality in febrile neutropenic patients with bloodstream infections (BSI) presenting with septic shock and assessed the impact of empirical antibiotic regimens.
Mariana Chumbita, P. Puerta-Alcalde, C. Gudiol, Nicole García-Poutón, J. Laporte-Amargós, A. Ladino, A. Albasanz-Puig, Cristina Helguera, A. Bergas, I. Grafia, E. Sastre, M. Suárez-Lledó, X. Durà, Carl Jordan, F. Marco, M. Condom, P. Castro, J. Martinez, J. Mensa, Á. Soriano, J. Carratalá, C. García-Vidal   +21 more
semanticscholar   +1 more source

Specific Removal of Monocytes from Peripheral Blood of Septic Patients by Polymyxin B-immobilized Filter Column [PDF]

, 2009
Lipopolysaccharide (LPS) is one of the major causes of septic shock. The polymyxin B-immobilized filter column (PMX) was developed for the adsorption of endotoxin by direct hemoperfusion and has been used for the treatment of LPS-induced septic shock. In
Iwagaki, Hiromi, Katayama, Hiroshi, Mori, Shuji, Morita, Kiyoshi, Nishibori, Masahiro, Ohtsuka, Aiji, Saito, Shinya, Takahashi, Hide K., Tanaka, Noriaki   +8 more
core   +1 more source

An overview of the mechanisms and potential roles of extracellular vesicles in septic shock

Frontiers in Immunology
Septic shock, a subset of sepsis, is a fatal condition associated with high morbidity and mortality. However, the pathophysiology of septic shock is not fully understood. Moreover, the diagnostic markers employed for identifying septic shock lack optimal
Meiling Cao, Mingyue Shi, Boru Zhou, Hongkun Jiang   +3 more
doaj   +1 more source

CD63 and C3AR1: The Potential Molecular Targets in the Progression of Septic Shock

International Journal of General Medicine, 2022
Ning Yu, Xuefang Liu, Dandan Shi, Long Bai, Tianfu Niu, Ya Liu Department of Anaesthesiology and Intensive Care, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, 050004, People’s Republic of ChinaCorrespondence: Ya Liu,
Yu N, Liu X, Shi D, Bai L, Niu T, Liu Y
doaj  

Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008

Intensive Care Medicine, 2007
ObjectiveTo provide an update to the original Surviving Sepsis Campaign clinical management guidelines, “Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock,” published in 2004.DesignModified Delphi method with a ...
R. Dellinger, Mitchell M. Levy, J. Carlet, Julian Bion, Margaret M. Parker, R. Jaeschke, K. Reinhart, D. Angus, C. Brun-Buisson, Richard J. Beale, Thierry Calandra, J. Dhainaut, H. Gerlach, Maurene Harvey, John J. Marini, John C. Marshall, Marco Ranieri, Graham Ramsay, J. Sevransky, B. T. Thompson, S. Townsend, J. Vender, Janice L. Zimmerman, Jean-Louis Vincent   +23 more
semanticscholar   +1 more source

Bioinformatic analysis identifies potential biomarkers and therapeutic targets of septic-shock-associated acute kidney injury

Hereditas, 2021
Background Sepsis and septic shock are life-threatening diseases with high mortality rate in intensive care unit (ICU). Acute kidney injury (AKI) is a common complication of sepsis, and its occurrence is a poor prognostic sign to septic patients.
Yun Tang, Xiaobo Yang, Huaqing Shu, Yuan Yu, Shangwen Pan, Jiqian Xu, You Shang   +6 more
doaj   +1 more source

Clinical solutions: not always what they seem? [PDF]

, 2015
Brenner and colleagues, in their article published in Critical Care, showed elevated levels of the reactive carbonyl species (RCS) methylglyoxal (MG) in the circulation of patients with septic shock.
Burke-Gaffney, A, Creagh-Brown, BC
core   +3 more sources

The effect of goal-directed therapy on mortality in patients with sepsis - earlier is better: A meta-analysis of randomized controlled trials [PDF]

, 2014
__Introduction:__ The Surviving Sepsis Campaign guidelines recommend goal-directed therapy (GDT) for the early resuscitation of patients with sepsis. However, the findings of the ProCESS (Protocolized Care for Early Septic Shock) trial showed no benefit ...
Bakker, J. (Jan), Gu, W.-J. (Wan-Jie), Liu, J.-C. (Jing-Chen), Tang, L. (Lu), Wang, F. (Fei)   +4 more
core   +4 more sources