Circulating Biologically Active Adrenomedullin Predicts Organ Failure and Mortality in Sepsis [PDF]
, 2019 BACKGROUND: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Biologically active adrenomedullin (bio-ADM) is an emerging biomarker for sepsis.
Bergmann, A. +4 more
core +1 more source
Hereditas, 2021 Background Sepsis and septic shock are life-threatening diseases with high mortality rate in intensive care unit (ICU). Acute kidney injury (AKI) is a common complication of sepsis, and its occurrence is a poor prognostic sign to septic patients.
Yun Tang +6 more
doaj +1 more source
Usefulness of ischemia-modified albumin in the diagnosis of sepsis/septic shock in the emergency department [PDF]
Clinical and Experimental Emergency Medicine, 2020 Objective No studies have evaluated the diagnostic value of ischemia-modified albumin (IMA) for the early detection of sepsis/septic shock in patients presenting to the emergency department (ED).
Seung Hwa Choo +6 more
doaj +1 more source
Cutoff Values of Hemodynamic Parameters in Pediatric Refractory Septic Shock
Children, 2022 Background: Refractory septic shock can cause severe morbidities and mortalities in children. Resuscitation based on hemodynamics is important in children with critical illness.
En-Pei Lee +5 more
doaj +1 more source
Circulating microparticles from septic shock patients exert differential tissue expression of enzymes related to inflammation and oxidative stress [PDF]
, 2011 Objective: Septic shock is characterized by hypotension and multiple organ failure after infection of microorganisms. Septic shock patients display high levels of circulating microparticles.
F. Meziani +5 more
core +3 more sources
International Journal of Pediatrics, 2019 Background. Paediatric septic shock is a subset of sepsis associated with high mortality. Implementing the existing international Surviving Sepsis Campaign Guidelines 2012 (SSCG) have contributed to reduction of mortality in many places but these have ...
Varsha Vekaria-Hirani +4 more
doaj +1 more source
Acute kidney injury is associated with a decrease in cortical renal perfusion during septic shock
Critical Care, 2018 Background Renal perfusion status remains poorly studied at the bedside during septic shock. We sought to measure cortical renal perfusion in patients with septic shock during their first 3 days of care using renal contrast enhanced ultrasound (CEUS ...
Anatole Harrois +3 more
doaj +1 more source
BMC Infectious Diseases, 2021 Background Identifying the biological subclasses of septic shock might provide specific targeted therapies for the treatment and prognosis of septic shock. It might be possible to find biological markers for the early prediction of septic shock prognosis.
Songchang Shi +5 more
doaj +1 more source
Empiric Antimicrobial Therapy in Patients with Healthcare-Associated, Hospital-Acquired, or Ventilator-Associated Pneumonia in Septic Shock: Does Antimicrobial Reuse Influence Outcomes? [PDF]
, 2017 Appropriate empiric antimicrobial selection is crucial to the survival of septic shock patients. It is suspected that the use of inadequate empiric therapy occurs commonly in practice.
Stagge, Nicole
core +1 more source
Specific Removal of Monocytes from Peripheral Blood of Septic Patients by Polymyxin B-immobilized Filter Column [PDF]
, 2009 Lipopolysaccharide (LPS) is one of the major causes of septic shock. The polymyxin B-immobilized filter column (PMX) was developed for the adsorption of endotoxin by direct hemoperfusion and has been used for the treatment of LPS-induced septic shock. In
Iwagaki, Hiromi +8 more
core +1 more source