Results 91 to 100 of about 3,633 (207)

6-Shogaol Abrogates Parkinson’s Disease in Rotenone-Induced Rodents: Based on In Silico Study and Inhibiting TNF-α/NF-κB/IL-1β/MAO-B

Pharmaceuticals
Background/Objectives: 6-Shogaol is a comparatively innovative anti-Parkinson’s remedy with antioxidant and anti-inflammatory characteristics. This investigation intended to determine the role of 6-shogaol in the Parkinson’s disease (PD) paradigm in ...
Misbahuddin Rafeeq, Fahad A. Al-Abbasi, Muhammad Afzal, Ehssan Moglad, Salwa D. Al-Qahtani, Sami I. Alzrea, Naif A. R. Almalki, Faisal Imam, Nadeem Sayyed, Imran Kazmi   +9 more
doaj   +1 more source

Formation of 6-, 8- and 10-Shogaol in Ginger through Application of Different Drying Methods: Altered Antioxidant and Antimicrobial Activity

Molecules, 2018
Gingerols and shogaols are compounds found in ginger (Zingiber officinale Roscoe); shogaols are found in lower concentration than gingerols but exhibit higher biological activities. This work studied the effects of different drying methods including open
Ali Ghasemzadeh, Hawa Z.E. Jaafar, Ali Baghdadi, Amin Tayebi-Meigooni   +3 more
doaj   +1 more source

PENGARUH SUHU TERHADAP KONSENTRASI GINGEROL DAN SHOGAOL HASIL EKSTRAKSI JAHE (Zingiber officinale) MENGGUNAKAN EKSTRAKTOR BERPENGADUK (Effect of Temperature on the Concentration of Gingerol and Shogaol Extracted from Ginger by Using Agitated Extractor) [PDF]

, 2018
Tanaman jahe termasuk Famili Zingiberaceae yang merupakan tanaman herba menahun, berakar serabut, dan termasuk kelas monokotil atau berkeping satu.
ARIFIANTO, INDRIYANA PUTRI
core   +1 more source

Unraveling the Immune Modulating Potential of Zingiber officinale Bioactive Compounds in Infants Born to Obese Mothers: a Network Pharmacology Approach [PDF]

Research Journal of Pharmacognosy
Background and objectives: Pregnant mothers with obesity may increase the risk of adverse health outcomes for their infants, such as weakened immune systems.
Novriantika Lestari, Melva Louisa*, Puspita Eka Wuyung, Fadilah Fadilah, Badriul Hegar   +4 more
doaj   +1 more source

3-Shogaol demonstrates antibacterial and antibiotic-potentiating effects against methicillin-resistant Staphylococcus aureus

Aims Shogaols, bioactive compounds derived from ginger (Zingiber officinale), exhibit diverse pharmacological properties. This study evaluated the antibacterial potential of 3-, 4-, 5-, 6-, 7-, 8-, 9-, and 10-shogaols, with emphasis ...
Yun Khoon Liew, Yee Ling Yong, Shawn Kai Jie Leong, Haseeb Ahmed Sayeed Khadas, Siang Han Lim, Lai Chun Wong, Vasudeva Rao Avupati, Lu Syuen Lim, Kitisak Ooi, Sin Yee Gan, Chun Wai Mai, Ngai Peng Lau, Yoon Yee Then, Xin Ying Ong, Wan Yi Chew   +14 more
core   +1 more source

Molecular docking study of ginger (Zingiber officinale) on Immunoglobulin A for smoking cessation [PDF]

Pharmacia
Smoking is a big problem that can cause death throughout the world. The main ingredient in cigarettes, nicotine, is toxic to humans in several ways. Quitting smoking with the help of medication is associated with adverse side effects such as drowsiness ...
Rika Mayasari Alamsyah, Mieke Hemiawati Satari, Sondang Pintauli, Shelly Iskandar   +3 more
doaj   +3 more sources

6-Shogaol enhances the chemotherapeutic efficacy of 5-fluorouracil through apoptosis induction and cell cycle arrest in MCF-7 breast cancer cells

Pharmacological Research - Modern Chinese Medicine
Background: Ginger (Zingiber officinale) has a long history of use in Traditional Chinese Medicine (TCM) as a “cure-all remedy”. 6-Shogaol, an essential bioactive element from dried ginger, has been widely used in traditional Chinese medicinal ...
Pitchakorn Sangchang, Chanokbhorn Phaosiri, Gulsiri Senawong, Pakit Kumboonma, Narissara Namwan, Thanaset Senawong   +5 more
doaj   +1 more source

Effect of 6-shogaol on viability and apoptosis in HCC cells.

, 2012
(A) The chemical structure of 6-shogaol. (B) SMMC-7721, BEL-7404 and HepG2 cells were treated with 5, 10, 15, 20, 25, 30, 40 and 50 µM 6-shogaol for 24 h respectively, and the cell viability was determined by MTT assay.
Yong-Bo Peng (153732), Xiaojun Xu (153741), Lei Zhang (38117), Qun Liu (67203), Xiao-Dong Wen (153765), Ning Gao (153779), Jiang Ma (153750), Lian-Wen Qi (153773), Rong Hu (153724), Ping Zhou (144535), Ping Li (31981)   +10 more
core   +1 more source

Characteristics and thermodynamics of the interaction of 6-shogaol with human serum albumin as studied by isothermal titration calorimetry

Brazilian Journal of Pharmaceutical Sciences
The interaction between 6-shogaol, a pharmacologically active ginger constituent, and human serum albumin (HSA), the main in vivo drug transporter, was investigated using isothermal titration calorimetry (ITC). The value of the binding constant, Ka (5.02
Shevin Rizal Feroz, Sri Nurestri Abdul Malek, Saad Tayyab   +2 more
doaj   +1 more source

6-shogaol against 3-Nitropropionic acid-induced Huntington's disease in rodents: Based on molecular docking/targeting pro-inflammatory cytokines/NF-κB-BDNF-Nrf2 pathway.

PLoS ONE
BackgroundHuntington's disease (HD) is an extremely harmful autosomal inherited neurodegenerative disease. Motor dysfunction, mental disorder, and cognitive deficits are the characteristic features of this disease.
Ebtihaj J Jambi, Abdulaziz Alamri, Muhammad Afzal, Fahad A Al-Abbasi, Salwa D Al-Qahtani, Naif A R Almalki, Azizah Salim Bawadood, Sami I Alzarea, Nadeem Sayyed, Imran Kazmi   +9 more
doaj   +1 more source