Results 101 to 110 of about 3,633 (207)

[6]-Shogaol Induces Apoptosis of Murine Bladder Cancer Cells

Cellular Physiology and Biochemistry
Background/Aims: Bladder cancer is considered one of the most aggressive neoplasms due to its recurrence and progression profile, and even with the improvement in diagnosis and treatment methods, the mortality rate has not shown a declining trend in recent decades.
Diana Gabriela, Nina Nina, Thaiane Alcarde, Robeldo, Almada da, Silva, Vitória Shiévila, Dos Santos Gonçalves, Ricardo Carneiro, Borra, Fernanda de Freitas, Anibal   +5 more
openaire   +2 more sources

PENGARUH JUMLAH PELARUT DAN SUHU EKSTRAKSI RIMPANG JAHE TERHADAP HASIL KADAR GINGEROL DAN SHOGAOL MENGGUNAKAN EKSTRAKTOR BERPENGADUK (The Effect of Solvent Amount and Temperature of Ginger Rhizome Extraction on The Results of Gingerol and Shogaol Content by Using Stirred Extractor)

, 2018
Ekstraksi merupakan proses pemisahan dan isolasi zat dari suatu zat dengan penambahan pelarut tertentu untuk mengeluarkan komponen campuran dari zat padat atau zat cair.
Pangesti, Syafa Nur
core   +1 more source

Prophylactic and therapeutic effects of (6)–shogaol on alveolar bone loss in experimental periodontitis

European Oral Research
Purpose: (6)-Shogaol is the most prevalent bioactive compound in ginger. The aim of this study was to examine both the prophylactic and therapeutic effects of (6)-shogaol in an experimental periodontitis model.Materials and Methods: Thirty-five male ...
Didem Bezirci, Meltem Karşıyaka Hendek, Gönen Özcan, Oğuz Kul, Tuğçe Anteplioğlu, Ebru Olgun   +5 more
doaj   +1 more source

6-Shogaol, a natural product, reduces cell death and restores motor function in rat spinal cord injury

, 2006
Spinal cord injury (SCI) results in progressive waves of secondary injuries, which via the activation of a barrage of noxious pathological mechanisms exacerbate the injury to the spinal cord.
J S Jung, Y G Kim, S K Kang, J S Woo, Hyo Kon Chun, J H Kim   +5 more
core   +1 more source

Structures of capsaicin, RTX, [6]-shogaol and [6]-gingerol.

, 2016
All four compounds possess a vanilloid moiety. Capsaicin and RTX have strong potency, while [6]-shogaol and [6]-gingerol have moderate potency against TRPV1.
Katsuya Ohbuchi (559460), Yoshikazu Mori (3032907), Takatsugu Hirokawa (59421), Kazuo Ogawa (652416), Eiji Warabi (640349), Masahiro Yamamoto (39398)   +5 more
core   +1 more source

Evaluation of antioxidant and antiproliferative activities of shogaol and its modulatory effects on key metabolic enzymes

Discover Food
Phenolic compounds are versatile bioactive molecules, particularly in food applications. In this study, the antioxidant capacity of Shogaol, a member of the phenolic class, was evaluated using several methods.
İsmail Yapıcı, İlhami Gülçin
doaj   +1 more source

Effects of 6-shogaol on ER stress signaling proteins.

, 2012
The cells were treated with or without 20 µM 6-shogaol for 1, 3, 6, 12, and 24 h. Total cellular extracts were prepared and subjected to Western blot analysis using antibodies against PARP, caspase-3 and ER stress-related molecular chaperones (A) and ER ...
Yong-Bo Peng (153732), Xiaojun Xu (153741), Lei Zhang (38117), Qun Liu (67203), Xiao-Dong Wen (153765), Ning Gao (153779), Jiang Ma (153750), Lian-Wen Qi (153773), Rong Hu (153724), Ping Zhou (144535), Ping Li (31981)   +10 more
core   +1 more source

Enzymatic reduction of shogaol: A novel biotransformation pathway for the alpha, beta-unsaturated ketone system

, 1992
A novel reductive metabolism of 1-(4-hydroxy-3-methoxyphenyl)-deca-4-ene-3-one (shogaol), a pungent principle of ginger, was investigated in rat liver in vitro.
Lee, SS, Surh, YJ
core  

Unraveling the interconversion pharmacokinetics and oral bioavailability of the major ginger constituents: [6]-gingerol, [6]-shogaol, and zingerone after single-dose administration in rats

Frontiers in Pharmacology
BackgroundThe available in vitro evidences suggest the inherent instability and interconvertibility of [6]-gingerol and [6]-shogaol. However, limited data on their in vivo interconversion hinder understanding of their influence on the pharmacokinetic ...
Phanit Songvut, Watanyoo Nakareangrit, Wanida Cholpraipimolrat, Jackapun Kwangjai, Luksamee Worasuttayangkurn, Piyajit Watcharasit, Piyajit Watcharasit, Jutamaad Satayavivad, Jutamaad Satayavivad   +8 more
doaj   +1 more source

Anti-invasion effects of 6-shogaol and 6-gingerol, two active components in ginger, on human hepatocarcinoma cells

, 2014
Scope: Hepatocellular carcinoma is the most common type of liver cancer and is highly metastatic. Metastasis is considered to be the major cause of death in cancer patients.
Weng, C.J., Yen, G.C., 顏國欽, Wu, C.F., Ho, C.T., Huang, H.W.   +5 more
core   +1 more source