Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes [PDF]
Pharmaceuticals, 2021 Ginger (Zingiber officinale Roscoe) is widely used as medicinal plant. According to the Committee on Herbal Medicinal Products (HMPC), dried powdered ginger rhizome can be applied for the prevention of nausea and vomiting in motion sickness (well ...
Robert Fürst, Iris Bischoff-Kont
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Prophylactic and therapeutic effects of (6)–shogaol on alveolar bone loss in experimental periodontitis [PDF]
European Oral Research, 2023 Purpose: (6)-Shogaol is the most prevalent bioactive compound in ginger. The aim of this study was to examine both the prophylactic and therapeutic effects of (6)-shogaol in an experimental periodontitis model.Materials and Methods: Thirty-five male ...
Didem Bezirci +5 more
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6-Shogaol Mitigates Sepsis-Associated Hepatic Injury through Transcriptional Regulation [PDF]
Nutrients, 2021 Sepsis-associated liver dysfunction presents a significant public health problem. 6-Shogaol is the key bioactive component in dry ginger, which has antioxidant and anti-inflammation capacity. The present study aims to investigate the preventive effect of 6-shogaol on sepsis-induced liver injury. 6-Shogaol was administered to mice for 7 consecutive days
Xiaoxuan Guo, Yongzhong Qian
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Ginger Constituent 6-Shogaol Inhibits Inflammation- and Angiogenesis-Related Cell Functions in Primary Human Endothelial Cells [PDF]
Frontiers in Pharmacology, 2022 Rhizomes from Zingiber officinale Roscoe are traditionally used for the treatment of a plethora of pathophysiological conditions such as diarrhea, nausea, or rheumatoid arthritis.
Iris Bischoff-Kont +5 more
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6-Shogaol inhibits HSCs activation and liver fibrosis by regulating glycolytic reprogramming via targeting HIF-1α [PDF]
Chinese MedicineBackground Liver fibrosis is a representative scarring response that can ultimately lead to liver cancer. However, relevant antifibrotic drugs for the effective treatment of liver fibrosis in humans have not yet been identified. 6-Shogaol is derived from
Junfa Yang +7 more
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Effects of 6-Shogaol on Glucose Uptake and Intestinal Barrier Integrity in Caco-2 Cells [PDF]
Foods, 2023 As the main bioactive component in dried ginger, 6-shogaol has potential hypoglycemic activity, but its mechanism is still unclear. The process of carbohydrate digestion and glucose absorption is closely related to the enzymatic activity of epithelial ...
Wenya Jiao +3 more
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Effect of 6-Shogaol on the Glucose Uptake and Survival of HT1080 Fibrosarcoma Cells [PDF]
Pharmaceuticals, 2019 Ginger is a plant that is native to southern China. In the last decade and research on the components of ginger has significantly increased; of these components, 6-shogaol exhibits the greatest potential antitumor capacity.
Angie C. Romero-Arias +3 more
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6-shogaol is a potential treatment for Head and Neck Squamous Cell Carcinoma. [PDF]
Int J Med Sci, 2023 Objective: Natural products in diet have shown a potential role in the prevention and treatment of cancer. Ginger (Zingiber officinale Roscoe) is a great candidate because of its properties of anti-inflammatory, antioxidant, and anti-cancer, but little is known about its effect on head and neck cancer.
Hsu CM +7 more
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6-Shogaol Inhibits the Cell Migration of Colon Cancer by Suppressing the EMT Process Through the IKKβ/NF-κB/Snail Pathway [PDF]
Integrative Cancer Therapies, 2023 6-Shogaol from ginger has anti-inflammatory, anti-oxidation and anti-cancer effects. Aim of the Study: To study the effects and possible mechanisms of 6-Shogaol on inhibiting the migration of colon cancer cells Caco2 and HCT116 and prove the effects on ...
Min Chen PhD +6 more
doaj +2 more sources
Anticancer effects of 6-shogaol via the AKT signaling pathway in oral squamous cell carcinoma [PDF]
Journal of Applied Oral Science, 2021 Objective Oral squamous cell carcinoma (OSCC) is one of the common type of cancer that leads to death; and is becoming a global concern. Due to the lack of efficient chemotherapeutic agents for patients with oral cancer, the prognosis remains poor.
Hai HUANG, Myoung-Ok KIM, Ki-Rim KIM
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