Results 31 to 40 of about 9,551,377 (187)
6-Shogaol and 10-Shogaol Synergize Curcumin in Ameliorating Proinflammatory Mediators via the Modulation of TLR4/TRAF6/MAPK and NFκB Translocation. [PDF]
Biomol Ther (Seoul), 2023 Extensive research supported the therapeutic potential of curcumin, a naturally occurring compound, as a promising cytokinesuppressive anti-inflammatory drug.
Zhou X +8 more
europepmc +2 more sources
6-Shogaol Overcomes Gefitinib Resistance via ER Stress in Ovarian Cancer Cells. [PDF]
Int J Mol Sci, 2023 In women, ovary cancer is already the fifth leading cause of mortality worldwide. The use of cancer therapies, such as surgery, radiotherapy, and chemotherapy, may be a powerful anti-cancer therapeutic strategy; however, these therapies still have many ...
Kim TW, Lee HG.
europepmc +2 more sources
Cysteine-Conjugated Metabolite of Ginger Component [6]-Shogaol Serves as a Carrier of [6]-Shogaol in Cancer Cells and in Mice [PDF]
Chemical Research in Toxicology, 2013 Shogaols, a series of major constituents in dried ginger (Zingiber officinale), show high anticancer potencies. Previously, we reported that a major metabolite resulting from the mercapturic acid pathway, 5-cysteinyl-[6]-shogaol (M2), showed comparable growth inhibitory effects toward cancer cells to [6]-shogaol (6S).
Huadong, Chen +5 more
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Biomolecules, 2020 Notably, 6-Shogaol, a bioactive natural substance, has anticancer effects on many types of tumors. Up to date, the anticancer effect and mode of action of 6-Shogaol on liposarcoma are not known.
Anil Kumar Yadav, Byeong-Churl Jang
doaj +1 more source
6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death. [PDF]
PLoS ONE, 2015 Cancer stem cells (CSCs) pose a serious obstacle to cancer therapy as they can be responsible for poor prognosis and tumour relapse. In this study, we have investigated inhibitory activity of the ginger-derived compound 6-shogaol against breast cancer ...
Anasuya Ray +2 more
doaj +1 more source
Molecules, 2017 Ginger has many bioactive compounds with pharmacological activities. However, few studies are known about these bioactive compounds activity in chemoresistant cells.
Chi-Ming Liu +4 more
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Heliyon, 2023 Ethnopharmacological relevance: Ginger (Zingiber officinale Roscoe) has been used for food and applied in Ayurvedic medicine in India for thousands of years.
Ha-Rim Kim, Eun-Mi Noh, Seon-Young Kim
doaj +1 more source
EVALUATION OF ANTIDEPRESSANT EFFECT OF 6-SHOGAOL IN ANIMAL MODELS
Current Research in Pharmaceutical Sciences, 2022 The objective of the study was therefore to evaluate the role of 6-shogaol in the antidepressant effect Zingiber officinale using two different animal models viz., tail suspension test and forced swim test. Ginger rhizomes were extracted using water-methanol (80/20) as the solvent using maceration and 6-shogaol was isolated from the extract using ...
PAYAL RAHANGDALE +3 more
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Analisis Bioinformatika 6-Shogaol sebagai Agen Antiproliferasi Kanker Payudara [PDF]
, 2022 Latar Belakang: Senyawa 6-shogaol adalah senyawa aktif dari jahe Zingiber officinale yang banyak dilaporkan aktivitas antikanker serta antiproliferasi nya.
AISY, Maitsaa Rihhadatul
core
6-shogaol suppresses oxidative damage in L6 muscle cells [PDF]
Applied Biological Chemistry, 2020 AbstractGinger (Zingiber Officinale Roscoe) has been known reduce muscle pain after exercise, and 6-shogaol {(E)-1-(4-Hydroxy-3-methoxyphenyl)dec-4-en-3-one)} is the major essential oil contained in ginger. In this study, the protective effect of 6-shogaol on L6 muscle cells against oxidative damage was measured.
Jinyoung Hur +4 more
openaire +1 more source