Results 171 to 180 of about 3,633 (207)

Interindividual Variability in Metabolism of [6]-Shogaol by Gut Microbiota

Journal of Agricultural and Food Chemistry, 2017
[6]-Shogaol (6S), one of the major bioactive components in dry ginger, is attracting considerable attention because of its wide spectrum of biological activities, but its metabolic fate is still not fully understood. In the present study, the microbial metabolism of 6S was examined for the first time in in vitro batch fecal fermentation system and in ...
Pei Wang, Ronghui Wang, Yingdong Zhu, Shengmin Sang   +3 more
openaire   +2 more sources

Gingerols and shogaols: Important nutraceutical principles from ginger

Phytochemistry, 2015
Gingerols are the major pungent compounds present in the rhizomes of ginger (Zingiber officinale Roscoe) and are renowned for their contribution to human health and nutrition. Medicinal properties of ginger, including the alleviation of nausea, arthritis and pain, have been associated with the gingerols.
Semwal, Ruchi Badoni, Semwal, Deepak Kumar, Combrinck, Sandra, Viljoen, Alvaro M.   +3 more
openaire   +3 more sources

Mutagenicity of gingerol and shogaol and antimutagenicity of zingerone in salmonella/microsome assay

Cancer Letters, 1987
Ginger extract and its constituents gingerol, shogaol and zingerone were tested in Salmonella typhimurium strains TA 100, TA 98, TA 1535 and TA 1538 in the presence and in absence of S9 mix. It was observed that ginger extract, gingerol and shogaol were mutagenic on metabolic activation in strains TA 100 and TA 1535, but zingerone was non-mutagenic in ...
M, Nagabhushan, A J, Amonkar, S V, Bhide
openaire   +2 more sources

6-Shogaol, a ginger product, modulates neuroinflammation: A new approach to neuroprotection

Neuropharmacology, 2012
Inflammatory processes in the central nervous system play an important role in a number of neurodegenerative diseases mediated by microglial activation, which results in neuronal cell death. Microglia act in immune surveillance and host defense while resting.
Sang Keun, Ha, Eunjung, Moon, Mi Sun, Ju, Dong Hyun, Kim, Jong Hoon, Ryu, Myung Sook, Oh, Sun Yeou, Kim   +6 more
openaire   +2 more sources

Conversion of gingerols to shogaols in ginger (Zingiber officinale roscoe) by puffing

Food Chemistry
Effect of puffing on conversion of gingerols to shogaols, physicochemical properties as well as antioxidant and anti-inflammatory activities of puffed ginger was investigated. Puffing significantly increased extraction yield and the highest value was 12.52% at 980 kPa.
Yoon-Tae, Kim, Jae-Sung, Shin, Sang-Jin, Ye, Ji Hye, Kim, Seok Hyun, Eom, Moo-Yeol, Baik   +5 more
openaire   +2 more sources

Stability of [6]-gingerol and [6]-shogaol in simulated gastric and intestinal fluids

Journal of Pharmaceutical and Biomedical Analysis, 2007
The degradation kinetics of [6]-gingerol and [6]-shogaol were investigated in simulated gastric (pH 1) and intestinal (pH 7.4) fluids at 37 degrees C. Degradation products were quantitatively determined by HPLC (Lichrospher 60 RP select B column, 5 microm, 125 mm x 4 mm; mobile phase: methanol-water-acetic acid (60:39:1 v/v); flow rate: 0.6 ml/min ...
Sushila, Bhattarai, Van H, Tran, Colin C, Duke   +2 more
openaire   +2 more sources

Gingerols and Shogaols from Food

2019
Wirginia Kukula-Koch, Lidia Czernicka
openaire   +2 more sources

Integrated network pharmacology and cellular assay for the investigation of an anti-obesity effect of 6-shogaol

Food Chemistry, 2022
Bimal Chitrakar, Xianghong Wang, Yaxin Sang   +2 more
exaly  

Metabonomics and the gut microbiome analysis of the effect of 6-shogaol on improving obesity

Food Chemistry, 2023
Xianghong Wang
exaly  

6-Shogaol inhibits the proliferation, apoptosis, and migration of rheumatoid arthritis fibroblast-like synoviocytes via the PI3K/AKT/NF-κB pathway

Phytomedicine, 2023
Jia-Xu Chen, Zhaohui Gong, Dongmei Pan
exaly