Results 31 to 40 of about 3,633 (207)
, 2022 Rhizomes from Zingiber officinale Roscoe are traditionally used for the treatment of a plethora of pathophysiological conditions such as diarrhea, nausea, or rheumatoid arthritis.
Thomas Zech (12136062) +4 more
core +1 more source
Pharmaceuticals, 2022 Although oxaliplatin is a well-known anti-cancer agent used for the treatment of colorectal cancer, treated patients often experience acute cold and mechanical allodynia as side effects. Unfortunately, no optimal treatment has been developed yet. In this
Suyong Kim +7 more
doaj +1 more source
Examination of the protective effect of 6-shogaol against LPS-induced acute lung injury in mice via NF-kB attenuation [PDF]
Archives of Biological Sciences, 2016 Acute lung injury (ALI), the causative factor for acute respiratory distress syndrome, results in significant morbidity and mortality. Due to a lack of effective therapeutic options for ALI, the development of novel therapies is urgently needed.
Wang Jing-Chao +3 more
doaj +1 more source
Antioxidants, 2023 6-shogaol is a natural and the most potent bioactive vanilloid in dried Zingiber officinale rhizomes. Many scientific studies have reported the diverse biological activities of 6-shogaol.
Kit-Kay Mak +7 more
doaj +1 more source
Shogaols from Zingiber officinale as Promising Antifouling Agents [PDF]
Bioscience, Biotechnology, and Biochemistry, 2002 We isolated the highly potent attachment-inhibitors (three times more active than standard CuSO4 in the blue mussel assay), trans-6-, 8-, and 10-shogaols, from a hexane extract of the roots of ginger, Zingiber officinale Roscoe. Trans-8-shogaol showed the highest antifouling activity comparable with that of tributyltin fluoride (TBTF), which is ...
ETOH, Hideo +6 more
openaire +2 more sources
8-Shogaol inhibits rheumatoid arthritis through targeting TAK1
Pharmacological Research, 2022 Rheumatoid arthritis (RA) is a chronic immune-mediated disorder, mainly characterized by synovial inflammation and joint damage. If insufficiently treated, RA can lead to irreversible joint destruction and decreased life expectancy. While better understanding of the pathologies and the development of new antirheumatic drugs have improved the outcome of
Seongin, Jo +11 more
openaire +2 more sources
, 2018 Activation of nuclear factor erythroid-2-related factor 2 (Nrf2) is a crucial cellular defense mechanisms against oxidative stress and also an effective means to decrease the risk of oxidative stress-related diseases including cancer.
Ya-Long Zheng (5541182) +5 more
core +1 more source
Molecules, 2019 Advanced glycation end-products (AGEs) cause diabetes mellitus (DM) complications and accumulate more highly in periodontal tissues of patients with periodontitis and DM.
Kohei Nonaka +6 more
doaj +1 more source
Metabolites of ginger component [6]-shogaol remain bioactive in cancer cells and have low toxicity in normal cells: chemical synthesis and biological evaluation. [PDF]
PLoS ONE, 2013 Our previous study found that [6]-shogaol, a major bioactive component in ginger, is extensively metabolized in cancer cells and in mice. It is unclear whether these metabolites retain bioactivity.
Yingdong Zhu +4 more
doaj +1 more source
Pharmaceuticals, 2023 Oxaliplatin is a chemotherapy drug that can induce severe acute neuropathy in patients within hours of treatment. In our previous study, 10 mg/kg [6]-shogaol (i.p.) significantly alleviated cold and mechanical allodynia induced by a 6 mg/kg oxaliplatin ...
Juan Gang +3 more
doaj +1 more source