Results 11 to 20 of about 3,633 (207)

6-Shogaol and 10-Shogaol Synergize Curcumin in Ameliorating Proinflammatory Mediators via the Modulation of TLR4/TRAF6/MAPK and NFκB Translocation

open access: yesBiomolecules & Therapeutics, 2022
Extensive research supported the therapeutic potential of curcumin, a naturally occurring compound, as a promising cytokinesuppressive anti-inflammatory drug. This study aimed to investigate the synergistic anti-inflammatory and anti-cytokine activities by combining 6-shogaol and 10-shogaol to curcumin, and associated mechanisms in modulating ...
Zhou, Xian (R17201)   +8 more
openaire   +6 more sources

Effect of 6-Shogaol on the Glucose Uptake and Survival of HT1080 Fibrosarcoma Cells

open access: yesPharmaceuticals, 2019
Ginger is a plant that is native to southern China. In the last decade and research on the components of ginger has significantly increased; of these components, 6-shogaol exhibits the greatest potential antitumor capacity.
Angie C. Romero-Arias   +3 more
doaj   +2 more sources

Anti-inflammatory effect and signaling mechanism of 8-shogaol and 10-shogaol in a dextran sodium sulfate-induced colitis mouse model

open access: yesHeliyon, 2023
Ethnopharmacological relevance: Ginger (Zingiber officinale Roscoe) has been used for food and applied in Ayurvedic medicine in India for thousands of years.
Ha-Rim Kim, Eun-Mi Noh, Seon-Young Kim
doaj   +3 more sources

The possibility of using shogaol for treatment of ulcerative colitis. [PDF]

open access: yesIranian journal of basic medical sciences, 2018
This study aimed to investigate the effect of Shogaol on dextran sodium sulfate (DSS)- induced ulcerative colitis (UC) in mice compared to an immune-suppressant chemotherapeutic medicine, known as 6-thioguanine (6-TG).Thirty-six adult BALB/c mice were divided into six groups: group 1 (positive control): no DSS exposure and no treatment; group 2 ...
Hassan, Snur, Hassan, Ali
openaire   +5 more sources

Effects of 6-Shogaol on Glucose Uptake and Intestinal Barrier Integrity in Caco-2 Cells

open access: yesFoods, 2023
As the main bioactive component in dried ginger, 6-shogaol has potential hypoglycemic activity, but its mechanism is still unclear. The process of carbohydrate digestion and glucose absorption is closely related to the enzymatic activity of epithelial ...
Wenya Jiao   +3 more
doaj   +2 more sources

6-shogaol, a neuroactive compound of ginger (jahe gajah) induced neuritogenic activity via NGF responsive pathways in PC-12 cells

open access: yesBMC Complementary and Alternative Medicine, 2017
Background Ginger is a popular spice and food preservative. The rhizomes of the common ginger have been used as traditional medicine to treat various ailments.
Syntyche Ling Sing Seow   +4 more
doaj   +2 more sources

Occurrence, biological activity and metabolism of 6-shogaol

open access: yesFood & Function, 2018
As one of the main bioactive compounds of dried ginger, 6-shogaol has been widely used to alleviate many ailments.
Xingran Kou   +9 more
openaire   +3 more sources

Shogaol, bisdemethoxycurcumin, and curcuminoid: Potential zingiber compounds against covid-19 [PDF]

open access: yes, 2021
Coronavirus disease (COVID-19) is a global pandemic in the world. Some treatments, including vaccines and potential drugs, are still developed. This study investigated the bioactive compounds of Zingiber officinale, Kaempferia rotunda, and Curcuma ...
I.R. Afrida, -
core   +2 more sources

Metabolism of [6]-Shogaol in Mice and in Cancer Cells [PDF]

open access: yesDrug Metabolism and Disposition, 2012
Ginger has received extensive attention because of its antioxidant, anti-inflammatory, and antitumor activities. However, the metabolic fate of its major components is still unclear. In the present study, the metabolism of [6]-shogaol, one of the major active components in ginger, was examined for the first time in mice and in cancer cells.
Huadong, Chen   +8 more
openaire   +3 more sources

6-Shogaol Inhibits the Cell Migration of Colon Cancer by Suppressing the EMT Process Through the IKKβ/NF-κB/Snail Pathway

open access: yesIntegrative Cancer Therapies, 2023
6-Shogaol from ginger has anti-inflammatory, anti-oxidation and anti-cancer effects. Aim of the Study: To study the effects and possible mechanisms of 6-Shogaol on inhibiting the migration of colon cancer cells Caco2 and HCT116 and prove the effects on ...
Min Chen PhD   +6 more
doaj   +1 more source

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