Results 21 to 30 of about 3,633 (207)
Notably, 6-Shogaol, a bioactive natural substance, has anticancer effects on many types of tumors. Up to date, the anticancer effect and mode of action of 6-Shogaol on liposarcoma are not known.
Anil Kumar Yadav, Byeong-Churl Jang
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6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death. [PDF]
Cancer stem cells (CSCs) pose a serious obstacle to cancer therapy as they can be responsible for poor prognosis and tumour relapse. In this study, we have investigated inhibitory activity of the ginger-derived compound 6-shogaol against breast cancer ...
Anasuya Ray +2 more
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Cysteine-Conjugated Metabolite of Ginger Component [6]-Shogaol Serves as a Carrier of [6]-Shogaol in Cancer Cells and in Mice [PDF]
Shogaols, a series of major constituents in dried ginger (Zingiber officinale), show high anticancer potencies. Previously, we reported that a major metabolite resulting from the mercapturic acid pathway, 5-cysteinyl-[6]-shogaol (M2), showed comparable growth inhibitory effects toward cancer cells to [6]-shogaol (6S).
Huadong, Chen +5 more
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Ginger has many bioactive compounds with pharmacological activities. However, few studies are known about these bioactive compounds activity in chemoresistant cells.
Chi-Ming Liu +4 more
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Zingiber officinale (Ginger) was widely known as one of the most herbal medicines containing many bioactive compounds claimed to be useful as an antioxidant, anti-inflammatory, anti-cancer, and anti-coagulant.
Devi Permatasari +2 more
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The glucuronidation pathways of shogaols ([6]-shogaol, [8]-shogaol and [10]-shogaol) were characterized in human tissues and recombinant human UDP-glucosyltransferases, and UGT2B7 was identified as the main contributor to their glucuronidation.
Liangliang He +8 more
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Ginger had been reported to ameliorate painful diabetic neuropathy (PDN) in an animal model. Gingerol and shogaol were active compounds of ginger that potentially act on transient receptor potential cation channel subfamily V member 1 (TRPV1), a key ...
Fifteen Aprila Fajrin +3 more
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Bio valorization and industrial applications of ginger waste: a review
The rapid increase in agricultural waste is rising across the globe and is a big environmental challenge. The utilization of ginger waste as a valuable product is very limited.
Rimsha Gulzar +10 more
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Analisis Bioinformatika 6-Shogaol sebagai Agen Antiproliferasi Kanker Payudara [PDF]
Latar Belakang: Senyawa 6-shogaol adalah senyawa aktif dari jahe Zingiber officinale yang banyak dilaporkan aktivitas antikanker serta antiproliferasi nya.
AISY, Maitsaa Rihhadatul
core
Zingiber officinale formulation reduces hepatic injury and weight gain in rats fed an unhealthy diet [PDF]
: This study investigated the ability of formulation containing Zingiber officinale (ginger) to reverse health changes promoted by unhealthy diet in Wistar rats. Five compounds from the gingerol family and three from the shogaol family were identified in
DALILA T. LEAL +7 more
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