Results 21 to 30 of about 3,633 (207)

Anti-Survival and Pro-Apoptotic Effects of 6-Shogaol on SW872 Human Liposarcoma Cells via Control of the Intrinsic Caspase Pathway, STAT-3, AMPK, and ER Stress

open access: yesBiomolecules, 2020
Notably, 6-Shogaol, a bioactive natural substance, has anticancer effects on many types of tumors. Up to date, the anticancer effect and mode of action of 6-Shogaol on liposarcoma are not known.
Anil Kumar Yadav, Byeong-Churl Jang
doaj   +1 more source

6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death. [PDF]

open access: yesPLoS ONE, 2015
Cancer stem cells (CSCs) pose a serious obstacle to cancer therapy as they can be responsible for poor prognosis and tumour relapse. In this study, we have investigated inhibitory activity of the ginger-derived compound 6-shogaol against breast cancer ...
Anasuya Ray   +2 more
doaj   +1 more source

Cysteine-Conjugated Metabolite of Ginger Component [6]-Shogaol Serves as a Carrier of [6]-Shogaol in Cancer Cells and in Mice [PDF]

open access: yesChemical Research in Toxicology, 2013
Shogaols, a series of major constituents in dried ginger (Zingiber officinale), show high anticancer potencies. Previously, we reported that a major metabolite resulting from the mercapturic acid pathway, 5-cysteinyl-[6]-shogaol (M2), showed comparable growth inhibitory effects toward cancer cells to [6]-shogaol (6S).
Huadong, Chen   +5 more
openaire   +2 more sources

Ginger Phytochemicals Inhibit Cell Growth and Modulate Drug Resistance Factors in Docetaxel Resistant Prostate Cancer Cell

open access: yesMolecules, 2017
Ginger has many bioactive compounds with pharmacological activities. However, few studies are known about these bioactive compounds activity in chemoresistant cells.
Chi-Ming Liu   +4 more
doaj   +1 more source

Simultaneous Isolation of 6-Gingerol, 6-Shogaol, and 6-Paradol from Zingiber Officinale Using Vaccum Liquid Chromatography

open access: yesSains Natural, 2022
Zingiber officinale (Ginger) was widely known as one of the most herbal medicines containing many bioactive compounds claimed to be useful as an antioxidant, anti-inflammatory, anti-cancer, and anti-coagulant.
Devi Permatasari   +2 more
doaj   +1 more source

Glucuronidation of [6]-shogaol, [8]-shogaol and [10]-shogaol by human tissues and expressed UGT enzymes: identification of UGT2B7 as the major contributor

open access: yesRSC Advances, 2018
The glucuronidation pathways of shogaols ([6]-shogaol, [8]-shogaol and [10]-shogaol) were characterized in human tissues and recombinant human UDP-glucosyltransferases, and UGT2B7 was identified as the main contributor to their glucuronidation.
Liangliang He   +8 more
openaire   +2 more sources

Molecular Docking Analysis of Ginger Active Compound on Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1)

open access: yesIndonesian Journal of Chemistry, 2018
Ginger had been reported to ameliorate painful diabetic neuropathy (PDN) in an animal model. Gingerol and shogaol were active compounds of ginger that potentially act on transient receptor potential cation channel subfamily V member 1 (TRPV1), a key ...
Fifteen Aprila Fajrin   +3 more
doaj   +1 more source

Bio valorization and industrial applications of ginger waste: a review

open access: yesInternational Journal of Food Properties, 2023
The rapid increase in agricultural waste is rising across the globe and is a big environmental challenge. The utilization of ginger waste as a valuable product is very limited.
Rimsha Gulzar   +10 more
doaj   +1 more source

Analisis Bioinformatika 6-Shogaol sebagai Agen Antiproliferasi Kanker Payudara [PDF]

open access: yes, 2022
Latar Belakang: Senyawa 6-shogaol adalah senyawa aktif dari jahe Zingiber officinale yang banyak dilaporkan aktivitas antikanker serta antiproliferasi nya.
AISY, Maitsaa Rihhadatul
core  

Zingiber officinale formulation reduces hepatic injury and weight gain in rats fed an unhealthy diet [PDF]

open access: yesAnais da Academia Brasileira de Ciências, 2019
: This study investigated the ability of formulation containing Zingiber officinale (ginger) to reverse health changes promoted by unhealthy diet in Wistar rats. Five compounds from the gingerol family and three from the shogaol family were identified in
DALILA T. LEAL   +7 more
doaj   +1 more source

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