Results 111 to 120 of about 7,270,008 (309)

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

open access: yesFEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Exploring the Therapeutic Effects of the ZhiZhu Pill on Rats with Chronic Transmission Constipation Based on Intestinal Microbiota and Metabolomics

open access: yesNatural Product Communications
Aim The effects of Atractylodes macrocephala Koidz. (Baizhu) and Citrus aurantium L. (Zhishi) (ZhiZhu pill, ZZP) on the defecation function, intestinal bacteria, and short-chain fatty acid metabolism of slow transit constipation (STC) rats were observed,
Lijuan Du   +4 more
doaj   +1 more source

Short-chain fatty acids in nonalcoholic fatty liver disease: New prospects for short-chain fatty acids as therapeutic targets

open access: yesHeliyon
Nonalcoholic fatty liver disease (NAFLD) is a stress-induced liver injury related to heredity, environmental exposure and the gut microbiome metabolism. Short-chain fatty acids (SCFAs), the metabolites of gut microbiota (GM), participate in the regulation of hepatic steatosis and inflammation through the gut-liver axis, which play an important role in ...
Xinyu Li   +7 more
openaire   +3 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Specificity of Mucor miehei lipase on methyl ester substrates

open access: yesGrasas y Aceites, 1993
Fatty acid methyl esters constitute a good substrate for the characterization of lipase typospecificity. In the present work, the hydrolytic action of lipase from Mucor miehei was studied. It was demonstrated that this lipase preferentially catalyses the
G Aggelis   +3 more
doaj   +1 more source

Investigations into β-ketoacyl-ACP Synthase III and enoyl-ACP reductase of plant fatty acid synthase [PDF]

open access: yes, 1999
An antisense transgenic approach was taken in order to assess the importance of P-ketoacyl-ACP- Synthase III (KAS III) in regulation and initiation of de novo fatty acid synthesis in planta.
Clarke, Hayley Diana
core  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

A short chain fatty acid–centric view of Clostridioides difficile pathogenesis

open access: yesPLoS Pathogens, 2021
Clostridioides difficile is an opportunistic diarrheal pathogen responsible for significant morbidity and mortality worldwide. A disrupted (dysbiotic) gut microbiome, commonly engendered by antibiotic treatment, is the primary risk factor for C ...
Anna L. Gregory   +2 more
doaj  

Reye's syndrome and short‐chain fatty acids [PDF]

open access: yesNeurology, 1985
Krause, Klaus-Henning   +2 more
openaire   +3 more sources

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

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