Results 41 to 50 of about 262,405 (315)

Associations between dysbiosis gut microbiota and changes of neurotransmitters and short-chain fatty acids in valproic acid model rats

open access: yesFrontiers in Physiology, 2023
Introduction: The microbiota–gut–brain axis plays an important role in the pathophysiology of autism spectrum disorder, but its specific mechanisms remain unclear.
Jiu-Gen Zhong   +10 more
doaj   +1 more source

Absorption of Short-Chain Fatty Acids by the Colon

open access: yesGastroenterology, 1980
Short-chain fatty acids (SCFAs) constitute the major solute fraction of normal stool water and are responsible for the diarrhea associated with carbohydrate (CHO) malabsorption. Although SCFA absorption from the human small bowel has been reported previously, the fate of SCFAs in the colon--their major site of production--was investigated in the ...
H, Ruppin   +4 more
openaire   +2 more sources

The Pharmacology and Function of Receptors for Short-Chain Fatty Acids [PDF]

open access: yesMolecular Pharmacology, 2016
Despite some blockbuster G protein-coupled receptor (GPCR) drugs, only a small fraction (∼ 15%) of the more than 390 nonodorant GPCRs have been successfully targeted by the pharmaceutical industry. One way that this issue might be addressed is via translation of recent deorphanization programs that have opened the prospect of extending the reach of new
Bolognini, Daniele   +3 more
openaire   +3 more sources

High-throughput analysis of total plasma fatty acid composition with direct in situ transesterification. [PDF]

open access: yes, 2010
Plasma fatty acid (FA) composition reflects dietary intake and endogenous turnover and is associated with health outcomes on a short and long term basis. The total plasma FA pool represents the composition of all FA containing lipid fractions.
Hans Demmelmair   +8 more
core   +1 more source

Short-chain fatty acids mediate enteric and central nervous system homeostasis in Parkinson’s disease: Innovative therapies and their translation

open access: yesNeural Regeneration Research
Short-chain fatty acids, metabolites produced by the fermentation of dietary fiber by gut microbiota, have garnered significant attention due to their correlation with neurodegenerative diseases, particularly Parkinson’s disease.
Shimin Pang   +3 more
doaj   +1 more source

Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs [PDF]

open access: yes, 2012
When it is difficult to develop selective ligands within a family of related G-protein-coupled receptors (GPCRs), chemically engineered receptors activated solely by synthetic ligands (RASSLs) are useful alternatives for probing receptor function. In the
Christiansen, Elisabeth   +16 more
core   +1 more source

The Urinary Microbiome; Axis Crosstalk and Short-Chain Fatty Acid

open access: yesDiagnostics, 2022
Our knowledge that “urine is sterile” is no longer accepted after the development of a next-generation sequencing (NGS) test. Using NGS, microbiota in the human body were discovered, and it is expected that this will improve our understanding of human ...
Hee Jo Yang   +3 more
doaj   +1 more source

Effects of induced subacute ruminal acidosis on milk fat content and milk fatty acid profile [PDF]

open access: yes, 2008
Two lactating dairy cows fitted with a rumen cannula received successively diets containing 0%, 20%, 34% and again 0% of wheat on a dry matter basis. After 5, 10 and 11 days, ruminal pH was measured between 8:00 and 16:00 hours, and milk was analysed for
Troegeler-Meynadier, Annabelle   +3 more
core   +1 more source

Effect of Fatty Acid Chain Length on Properties of Rice Starch-Fatty Acid Complexes

open access: yesShipin gongye ke-ji
Rice starch-fatty acid complexes were prepared by compounding rice starch with different chain lengths of lauric acid (C12), myristic acid (C14), and palmitic acid (C16). By measuring the composite index, gelatinization properties, rheological properties,
Jianhui JIA   +6 more
doaj   +1 more source

Determination of short chain fatty acids isomers, the sensory active products of hops aging, in beer.

open access: yesKvasný průmysl, 2013
Important products of hop aging are the C4 and C5 isomers of short chain fatty acids; namely 2-methyl propionic acid (isobutyric acid), 2-methyl butyric acid and 3-methyl butyric acid (isovaleric acid).
Jiří ČULÍK   +4 more
doaj   +1 more source

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