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Short-chain fatty acids [PDF]

, 2021
Global obesity rates are increasing more and more. Short-chain fatty acids, the end products of fermentation of indigestible carbohydrates by intestinal bacteria, can influence metabolism and therefore play a role in the development of obesity and diabetes.
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Short-Chain Fatty Acids [PDF]

, 2020
The relationship between diet and the diversity and function of the intestinal microbiomeand its importance for human health is currently the subject of many studies. The type and proportionof microorganisms found in the intestines can determine the energy balance of the host.
Paulina Markowiak-Kopeć, Katarzyna Śliżewska   +1 more
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Short Chain Fatty Acids and Colon Cancer [PDF]

The Journal of Nutrition, 2002
The development of intestinal cancer involves complex genetic and epigenetic alterations in the intestinal mucosa. The principal signaling pathway responsible for the initiation of tumor formation, the APC-beta-catenin-TCF4 pathway, regulates both cell proliferation and colonic cell differentiation, but many other intrinsic and extrinsic signals also ...
Leonard H, Augenlicht, John M, Mariadason, Andrew, Wilson, Diego, Arango, WanCai, Yang, Barbara G, Heerdt, Anna, Velcich   +6 more
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Short-chain fatty acid acetate stimulates adipogenesis and mitochondrial biogenesis via GPR43 in brown adipocytes [PDF]

, 2016
Short-chain fatty acids play crucial roles in a range of physiological functions. However, the effects of short-chain fatty acids on brown adipose tissue have not been fully investigated.
GK Dimitriadis (7772033), Kyrou, Ioannis, Tan, B.K, G Tripathi (7804103), J Hu (7741025), V Patel (7804106), Patel, V., Dimitriadis, G.K, Chen, J, Dimitriadis, Georgios K., Ramanjaneya, M., Ramanjaneya, M, Tripathi, G, Tan B.K., I Kyrou (7772027), Ramanjaneya, Manjunath, James, Sean G., Tripathi, G., S James (7748780), Patel, Vanlata H., James, Sean, J Chen (80904), Hu, Jiamiao, Hu, J, Kawan, M, Hu, J., Tan, Bee K., Kawan, Mohamed, M Kawan (7804109), James, S, Tripathi, Gyanendra, Kawan, M., Kyrou, I, James, S., Randeva, Harpal S., M Ramanjaneya (7804100), Kyrou, I., Chen, J., HS Randeva (7772048), Patel, V, BK Tan (7718081), Patel, Vanlata, Dimitriadis, G.K., Randeva, H.S., Randeva, H.S, Chen, Jing   +45 more
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NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells

Cell Reports, 2019
Summary: Autophagy plays a critical role in the maintenance of immunological memory. However, the molecular mechanisms involved in autophagy-regulated effector memory formation in CD8+ T cells remain unclear. Here we show that deficiency in NIX-dependent
Shubhranshu S. Gupta, Robert Sharp, Colby Hofferek, Le Kuai, Gerald W. Dorn, II, Jin Wang, Min Chen   +6 more
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Inverse Association between trans Isomeric and Long-Chain Polyunsaturated Fatty Acids in Pregnant Women and Their Newborns: Data from Three European Countries [PDF]

, 2011
Background: trans unsaturated fatty acids are thought to interfere with essential fatty acid metabolism. To extend our knowledge of this phenomenon, we investigated the relationship between trans isomeric and long-chain polyunsaturated fatty acids ...
Krauss-Etschmann, S., É. Szabó, Marosvolgyi, Tamas, Campoy, C., T. Marosvölgyi, Decsi, Tamás, Marosvölgyi, T., C. Campoy, B. Koletzko, M. Escolano, Campoy, Cristina, Cruz, M., Szabó, É., Krauss-Etschmann, Susanne, S. Krauss-Etschmann, M. Cruz, Szabo, Eva, Escolano, M., Marchal, G., T. Decsi, Koletzko, Berthold, H. Demmelmair, Demmelmair, Hans, G. Marchal   +23 more
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Three-year tracking of fatty acid composition of plasma phospholipids in healthy children [PDF]

, 2007
Objectives: The fatty acid composition of plasma phospholipids reflects the dietary fatty acid intake as well as endogenous turnover. We aimed at investigating the potential tracking of plasma phospholipid fatty acid composition in children that ...
Toschke, Andre Michael, Guerra, Antonio, Koletzko, Berthold, Demmelmair, Hans   +3 more
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Parkinson’s disease patients’ short chain fatty acids production capacity after in vitro fecal fiber fermentation

npj Parkinson's Disease, 2021
Animal models indicate that butyrate might reduce motor symptoms in Parkinson’s disease. Some dietary fibers are butyrogenic, but in Parkinson’s disease patients their butyrate stimulating capacity is unknown.
Florence Baert, Christophe Matthys, Jarissa Maselyne, Christof Van Poucke, Els Van Coillie, Bruno Bergmans, Geertrui Vlaemynck   +6 more
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Regulation of Inflammation by Short Chain Fatty Acids [PDF]

Nutrients, 2011
The short chain fatty acids (SCFAs) acetate (C2), propionate (C3) and butyrate (C4) are the main metabolic products of anaerobic bacteria fermentation in the intestine. In addition to their important role as fuel for intestinal epithelial cells, SCFAs modulate different processes in the gastrointestinal (GI) tract such as electrolyte and water ...
Vinolo, Marco A.R., Rodrigues, Hosana G., Nachbar, Renato T., Curi, Rui   +3 more
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Short-chain fatty acids in cancer pathogenesis

Cancer and Metastasis Reviews, 2023
AbstractCancer is a multi-step process that can be viewed as a cellular and immunological shift away from homeostasis in response to selected infectious agents, mutations, diet, and environmental carcinogens. Homeostasis, which contributes importantly to the definition of “health,” is maintained, in part by the production of short-chain fatty acids ...
Mark A. Feitelson, Alla Arzumanyan, Arvin Medhat, Ira Spector   +3 more
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