Engineering fungal de novo fatty acid synthesis for short chain fatty acid production
The production of short chain fatty acids by microorganisms has numerous industrial and biofuel applications. Here the authors reprogrammeS. cerevisiaefatty acid synthase with five mutations to produce C6- and C8-fatty acids and identify thioesterases ...
Jan Gajewski +4 more
doaj +1 more source
Differences in fatty acid composition between cerebral brain lobes in juvenile pigs after fish oil feeding [PDF]
Very long-chain n-3 PUFA from fish are suggested to play a role in the development of the brain. Fish oil feeding results in higher proportions of n-3 PUFA in the brains of newborn piglets. However, the effect of fish oil on the fatty acid composition of
Coronel, R. +22 more
core +1 more source
Allosteric modulation of zinc speciation by fatty acids [PDF]
Background: Serum albumin is the major protein component of blood plasma and is responsible for the circulatory transport of a range of small molecules that include fatty acids, hormones, metal ions and drugs.
Sadler, P. J. +6 more
core +2 more sources
Essential fatty acids and their long-chain polyunsaturated metabolites in maternal and cord plasma triglycerides during late gestation [PDF]
The fatty acid composition of plasma lipids was determined in 41 pairs of mothers and their term infants at time of birth (38-42 postmenstrual weeks) by high-resolution capillary gas-liquid chromatography, Linoleic and alpha-linolenic acids were found at
Koletzko, Berthold +2 more
core +1 more source
The roles of long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy: review of current knowledge and consensus recommendations. [PDF]
This paper reviews current knowledge on the role of the long-chain polyunsaturated fatty acids (LC-PUFA), docosahexaenoic acid (DHA, C22:6n-3) and arachidonic acid (AA, 20:4n-6), in maternal and term infant nutrition as well as infant development ...
Alexandre Lapillonne +63 more
core +1 more source
Butyrate and propionate represent two of three main short-chain fatty acids produced by the intestinal microbiota. In healthy populations, their levels are reportedly equimolar, whereas a deviation in their ratio has been observed in various diseased ...
Pranvera Hiseni +5 more
doaj +1 more source
Placental transfer of long-chain polyunsaturated fatty acids (LC-PUFA) [PDF]
Considerable evidence exists for marked beneficial effects of omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) during pregnancy. The omega-3 LCPUFA docosahexaenoic acid (DHA) is incorporated in large amounts in fetal brain and other tissues ...
Hans Demmelmair +5 more
core +2 more sources
De novo fatty acid synthesis and elongation of fatty acids by subcellular fractions of lung
Fatty acid synthesis by subcellular fractions of rabbit lung was studied by measuring the incorporation of either radioactive acetyl coenzyme A or malonyl coenzyme A into long-chain fatty acids.
HARVEY SCHILLER, KLAUS BENSCH
doaj +1 more source
Regulation of short-chain fatty acid production [PDF]
Short-chain fatty acid (SCFA) formation by intestinal bacteria is regulated by many different host, environmental, dietary and microbiological factors. In broad terms, however, substrate availability, bacterial species composition of the microbiota and intestinal transit time largely determine the amounts and types of SCFA that are produced in healthy ...
Sandra, Macfarlane, George T, Macfarlane
openaire +2 more sources
FADS Gene Cluster Polymorphisms: Important Modulators of Fatty Acid Levels and Their Impact on Atopic Diseases [PDF]
Long-chain polyunsaturated fatty acids (LC-PUFAs) play an important role in several physiological processes and their concentration in phospholipids has been associated with several complex diseases, such as atopic disease.
Lattka, E. +7 more
core +1 more source

