Results 251 to 260 of about 400,864 (307)

Commensal-derived short-chain fatty acids disrupt lipid membrane homeostasis in <i>Staphylococcus aureus</i>. [PDF]

mBio
Fletcher JR, Hansen LA, Hoyser JR, Hanna AE, Martinez R, Freeman CD, Thorns NT, Penningroth MR, Villarreal AR, Vogt GA, Tyler MA, Hines KM, Hunter RC.   +12 more
europepmc   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

Members of Lachnospiraceae produce valerate and caproate in response to short-chain fatty acids. [PDF]

Microbiome
Fitzgerald BG, Govind M, Firth IJ, Herold L, Froment J, Vancuren SJ, Allen-Vercoe E, Kimber MS, Sorbara MT.   +8 more
europepmc   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

Modifying microbially derived short chain fatty acids to promote health. [PDF]

J Physiol
Ornelas A, Countess JA, Kim JY, Colgan SP.   +3 more
europepmc   +1 more source

Improving Oxidative Stress Through a Wheat Aleurone-Rich Diet: Are Short-Chain Fatty Acids Possible Mediators? [PDF]

Nutrients
Testa R, Salamone D, Rivellese AA, Riccardi G, Vitale M, Giacco R, Costabile G.   +6 more
europepmc   +1 more source

Investigation of Intestinal Microbiota and Short-Chain Fatty Acids in Colorectal Cancer and Detection of Biomarkers. [PDF]

Pathogens
Saylam E, Özden Ö, Yerlikaya FH, Sivrikaya A, Yormaz S, Arslan U, Topkafa M, Maçin S.   +7 more
europepmc   +1 more source

Deciphering the modulatory role of short-chain fatty acids in Parkinson's disease <i>via</i> phosphorylation-dependent signaling mechanisms. [PDF]

PeerJ
Liu J, Su R.
europepmc   +1 more source

Short-chain fatty acids mediate interactions between immune responses and commensal bacteria in high altitude yaks. [PDF]

Commun Biol
Guo N, Gou N, Shi F, Wang W, Li S, Bi S, Jiao J, Luo B, Huang M, Degen AA, Shang Z.   +10 more
europepmc   +1 more source