Results 71 to 80 of about 405,625 (304)

The effects of species ortholog and SNP variation on receptors for free fatty acids [PDF]

open access: yes, 2013
Although it is widely assumed that species orthologs of hormone responsive G protein-coupled receptors will be activated by the same endogenously produced ligand(s), variation in potency, particularly in cases where more than one receptor responds to the
1000 Genomes Project Consortium   +72 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Phospholipid and triglyceride metabolism of excised rat diaphragm and the role of these lipids in fatty acid uptake and oxidation*

open access: yesJournal of Lipid Research, 1960
After a 48-hour fast, the phospholipid fatty acids of rat diaphragm are reduced much more than the triglyceride fatty acids. Phospholipid thus appears to contribute more to the labile fatty acids than triglyceride.
E.M. Neptune, Jr.   +3 more
doaj   +1 more source

Acute oral sodium propionate supplementation raises resting energy expenditure and lipid oxidation in fasted humans [PDF]

open access: yes, 2018
Short chain fatty acids (SCFAs), produced from fermentation of dietary fibre by the gut microbiota, have been suggested to modulate energy metabolism. Previous work using rodent models have demonstrated that oral supplementation of the SCFA propionate ...
Baldwin   +19 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Identification and Analyses of Short Chain Fatty Acids in Apple Seed Parts During Stratification [PDF]

open access: yes, 1994
Penelitian ini bertujuan untuk mengidentifikasi dan menganalisis Perubahan kandungan asam lemak rantai pendek (ALRP) pada biji apel selama stratifikasi.
Powell, L. E. (Loyd)   +1 more
core  

The therapeutic potential of allosteric ligands for free fatty acid sensitive GPCRs [PDF]

open access: yes, 2013
G protein coupled receptors (GPCRs) are the most historically successful therapeutic targets. Despite this success there are many important aspects of GPCR pharmacology and function that have yet to be exploited to their full therapeutic potential.
Hudson, Brian D.   +2 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Effect of Fatty Acid Chain Length on Properties of Rice Starch-Fatty Acid Complexes

open access: yesShipin gongye ke-ji
Rice starch-fatty acid complexes were prepared by compounding rice starch with different chain lengths of lauric acid (C12), myristic acid (C14), and palmitic acid (C16). By measuring the composite index, gelatinization properties, rheological properties,
Jianhui JIA   +6 more
doaj   +1 more source

Evaluation of the hypocholesterolemic effect and prebiotic activity of a lentil (Lens culinaris Medik) extract

open access: yes, 2017
The aim of our work was to produce a hydroalcoholic extract of lentils and to examine: a) the hypocholesterolemic action in an animal model, by studying the plasma cholesterol level and the concentration of bile acids in the faeces; b) the potential ...
Bingham   +20 more
core   +1 more source

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