Results 11 to 20 of about 4,886,903 (295)
, 2022 Alternative splicing can lead to distinct protein isoforms. These can have different functions in specific cells and tissues or in different developmental stages.
Aidan P. Tay (1538278) +4 more
core +4 more sources
Investigating the Performance of Oxford Nanopore Long-Read Sequencing with Respect to Illumina Microarrays and Short-Read Sequencing [PDF]
International Journal of Molecular SciencesClaire Troakes +2 more
exaly +2 more sources
An analysis of the feasibility of short read sequencing [PDF]
Nucleic Acids Research, 2005 Several methods for ultra high-throughput DNA sequencing are currently under investigation. Many of these methods yield very short blocks of sequence information (reads). Here we report on an analysis showing the level of genome sequencing possible as a function of read length.
Whiteford, N. +7 more
openaire +6 more sources
Comparative Meta-Analysis of Long-Read and Short-Read Sequencing for Metagenomic Profiling of the Lower Respiratory Tract Infections [PDF]
MicroorganismsLorenzin G, Carlin M.
exaly +2 more sources
Short read sequence typing (SRST): multi-locus sequence types from short reads [PDF]
BMC Genomics, 2012 Abstract Background Multi-locus sequence typing (MLST) has become the gold standard for population analyses of bacterial pathogens. This method focuses on the sequences of a small number of loci (usually seven) to divide the population and is simple, robust and facilitates comparison of results between laboratories ...
Inouye, M +3 more
openaire +4 more sources
Estimation of sequencing error rates in short reads [PDF]
BMC Bioinformatics, 2012 Abstract Background Short-read data from next-generation sequencing technologies are now being generated across a range of research projects. The fidelity of this data can be affected by several factors and it is important to have simple and reliable approaches for monitoring it at the level of individual experiments.
Blades, Natalie +4 more
openaire +5 more sources
African Journal of Laboratory Medicine, 2020 No abstract available.
Boluwatife A. Adewale
doaj +1 more source
Long-Read Sequencing Annotation of the Transcriptome in DNA-PK Inactivated Cells
Frontiers in Oncology, 2022 The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) with a Ku70/Ku80 heterodimer constitutes the intact DNA-PK kinase, which is an upstream component of the DNA repair machinery that signals the DNA damage, orchestrates the DNA repair, and ...
Liwei Song +10 more
doaj +1 more source
Microindel detection in short-read sequence data [PDF]
Bioinformatics, 2010 Abstract Motivation: Several recent studies have demonstrated the effectiveness of resequencing and single nucleotide variant (SNV) detection by deep short-read sequencing platforms. While several reliable algorithms are available for automated SNV detection, the automated detection of microindels in deep short-read data presents a new ...
Peter M. Krawitz +5 more
openaire +5 more sources
mSystems, 2022 Long-read sequencing offers the potential to improve metagenome assemblies and provide more robust assessments of microbial community composition and function than short-read sequencing.
N. V. Patin, K. D. Goodwin
doaj +1 more source