Results 21 to 30 of about 308,842 (252)
Detection of trait-associated structural variations using short-read sequencing [PDF]
Cell Genomics, 2023 Shunichi Kosugi +2 more
exaly +2 more sources
Impact of short-read sequencing on the misassembly of a plant genome. [PDF]
BMC Genomics, 2021 Abstract Background: Availability of plant genome sequences has led to significant advances. However, with few exceptions, the great majority of existing genome assemblies are derived from short read sequencing technologies with highly uneven read coverages indicative of sequencing and assembly issues that could significantly impact any ...
Wang P, Meng F, Moore BM, Shiu SH.
europepmc +5 more sources
Investigating the Performance of Oxford Nanopore Long-Read Sequencing with Respect to Illumina Microarrays and Short-Read Sequencing [PDF]
International Journal of Molecular SciencesRenato Santos +2 more
exaly +2 more sources
An analysis of the feasibility of short read sequencing [PDF]
Nucleic Acids Research, 2005 Several methods for ultra high-throughput DNA sequencing are currently under investigation. Many of these methods yield very short blocks of sequence information (reads). Here we report on an analysis showing the level of genome sequencing possible as a function of read length.
Whiteford, N. +7 more
openaire +6 more sources
Short read sequence typing (SRST): multi-locus sequence types from short reads [PDF]
BMC Genomics, 2012 Abstract Background Multi-locus sequence typing (MLST) has become the gold standard for population analyses of bacterial pathogens. This method focuses on the sequences of a small number of loci (usually seven) to divide the population and is simple, robust and facilitates comparison of results between laboratories ...
Inouye, M +3 more
openaire +4 more sources
Estimation of sequencing error rates in short reads [PDF]
BMC Bioinformatics, 2012 Abstract Background Short-read data from next-generation sequencing technologies are now being generated across a range of research projects. The fidelity of this data can be affected by several factors and it is important to have simple and reliable approaches for monitoring it at the level of individual experiments.
Blades, Natalie +4 more
openaire +5 more sources
mSystems, 2022 Long-read sequencing offers the potential to improve metagenome assemblies and provide more robust assessments of microbial community composition and function than short-read sequencing.
N. V. Patin, K. D. Goodwin
doaj +1 more source
Microindel detection in short-read sequence data [PDF]
Bioinformatics, 2010 Abstract Motivation: Several recent studies have demonstrated the effectiveness of resequencing and single nucleotide variant (SNV) detection by deep short-read sequencing platforms. While several reliable algorithms are available for automated SNV detection, the automated detection of microindels in deep short-read data presents a new ...
Peter M. Krawitz +5 more
openaire +4 more sources
Long-Read Sequencing Annotation of the Transcriptome in DNA-PK Inactivated Cells
Frontiers in Oncology, 2022 The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) with a Ku70/Ku80 heterodimer constitutes the intact DNA-PK kinase, which is an upstream component of the DNA repair machinery that signals the DNA damage, orchestrates the DNA repair, and ...
Liwei Song +10 more
doaj +1 more source
Fast search of thousands of short-read sequencing experiments [PDF]
Nature Biotechnology, 2016 The amount of sequence information in public repositories is growing at a rapid rate. Although these data are likely to contain clinically important information that has not yet been uncovered, our ability to effectively mine these repositories is limited.
Solomon, Brad, Kingsford, Carl
openaire +2 more sources