Results 51 to 60 of about 405,626 (304)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Potential Effects of Short-Chain Fatty Acids on the Epigenetic Regulation of Innate Immune Memory

open access: yesChallenges, 2020
The regulation of innate immunity is substantially more ‘plastic’ than previously appreciated. Innate immune memory (manifested through trained immunity and tolerance) is a recently described epigenetic phenomenon that is a model example, with broad ...
Raphael Watt   +2 more
doaj   +1 more source

Does canine inflammatory bowel disease influence gut microbial profile and host metabolism? [PDF]

open access: yes, 2016
Background: Inflammatory bowel disease (IBD) refers to a diverse group of chronic gastrointestinal diseases, and gut microbial dysbiosis has been proposed as a modulating factor in its pathogenesis.
Bosch, Guido   +13 more
core   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

G-protein-coupled receptors for free fatty acids: nutritional and therapeutic targets [PDF]

open access: yes, 2014
It is becoming evident that nutrients and metabolic intermediates derived from such nutrients regulate cellular function by activating a number of cell-surface G-protein coupled receptors (GPCRs).
Brian D. Hudson   +6 more
core   +2 more sources

Nuts, bolts and short-chain fatty acids [PDF]

open access: yesCanadian Medical Association Journal, 2011
I recall precisely two lectures on nutrition in medical school. True, we heard physiology lectures on short-chain fatty acids, and our biochemistry professors encouraged us to remember the structures of the amino acids, but just how these things related to what a person should eat remained ...
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

(Tinjauan Pustaka) Efek Perbedaan Sumber Dan Struktur Kimia Asam Lemak Jenuh Terhadap Kesehatan [PDF]

open access: yes, 2010
. For decades, all saturated fatty acids have always been judged as the only cause of cardiovascular disease without considering the difference of their sources and the length of their carbon chains.
Tuminah, S. (Sulistyowati)
core  

Preparation and characterization of highly pure fractions of outer membrane, cytoplasmic and intracytoplasmic membranes from Ectothiorhodospira mobilis [PDF]

open access: yes, 1993
Outer membrane (OM), cytoplasmic membrane (CM) and intracytoplasmic membranes (ICM) from the halophilic phototrophic purple sulphur bacterium Ectothiorhodospira mobilis 9903 were purified and characterized. The three membrane fractions were significantly
Ditandy, Toni, Imhoff, Johannes F.
core   +1 more source

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