Results 51 to 60 of about 405,626 (304)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The regulation of innate immunity is substantially more ‘plastic’ than previously appreciated. Innate immune memory (manifested through trained immunity and tolerance) is a recently described epigenetic phenomenon that is a model example, with broad ...
Raphael Watt +2 more
doaj +1 more source
Does canine inflammatory bowel disease influence gut microbial profile and host metabolism? [PDF]
Background: Inflammatory bowel disease (IBD) refers to a diverse group of chronic gastrointestinal diseases, and gut microbial dysbiosis has been proposed as a modulating factor in its pathogenesis.
Bosch, Guido +13 more
core +2 more sources
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
G-protein-coupled receptors for free fatty acids: nutritional and therapeutic targets [PDF]
It is becoming evident that nutrients and metabolic intermediates derived from such nutrients regulate cellular function by activating a number of cell-surface G-protein coupled receptors (GPCRs).
Brian D. Hudson +6 more
core +2 more sources
Nuts, bolts and short-chain fatty acids [PDF]
I recall precisely two lectures on nutrition in medical school. True, we heard physiology lectures on short-chain fatty acids, and our biochemistry professors encouraged us to remember the structures of the amino acids, but just how these things related to what a person should eat remained ...
openaire +2 more sources
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
(Tinjauan Pustaka) Efek Perbedaan Sumber Dan Struktur Kimia Asam Lemak Jenuh Terhadap Kesehatan [PDF]
. For decades, all saturated fatty acids have always been judged as the only cause of cardiovascular disease without considering the difference of their sources and the length of their carbon chains.
Tuminah, S. (Sulistyowati)
core
Preparation and characterization of highly pure fractions of outer membrane, cytoplasmic and intracytoplasmic membranes from Ectothiorhodospira mobilis [PDF]
Outer membrane (OM), cytoplasmic membrane (CM) and intracytoplasmic membranes (ICM) from the halophilic phototrophic purple sulphur bacterium Ectothiorhodospira mobilis 9903 were purified and characterized. The three membrane fractions were significantly
Ditandy, Toni, Imhoff, Johannes F.
core +1 more source

