Results 61 to 70 of about 197,388 (261)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Effects of the gut microbiota and its metabolite short-chain fatty acids on endometriosis
Frontiers in Cellular and Infection MicrobiologyIn recent years, a growing body of research has confirmed that the gut microbiota plays a major role in the maintenance of human health and disease. A gut microbiota imbalance can lead to the development of many diseases, such as pregnancy complications,
Menghe Liu +8 more
doaj +1 more source
Diabetic wounds and short-chain fatty acids
Journal of Diabetes & Metabolic DisordersDiabetes mellitus is a debilitating and worrisome chronic disease with many complications such as cardiovascular disease, kidney damage, blindness and diabetic wounds. Despite advances in the treatment of diabetic wounds, there are still concerns regarding the management of diabetic wound healing, particularly the inflammatory phase.
Zahra Rezaeiasl, Mahmoud Salami Zavareh
openaire +2 more sources
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Gut microbiota facilitate chronic spontaneous urticaria
Nature CommunicationsChronic spontaneous urticaria (CSU) comes with gut dysbiosis, but its relevance remains elusive. Here we use metagenomics sequencing and short-chain fatty acids metabolomics and assess the effects of human CSU fecal microbial transplantation, Klebsiella ...
Lei Zhu +10 more
doaj +1 more source
Kvasný průmysl, 2013 Important products of hop aging are the C4 and C5 isomers of short chain fatty acids; namely 2-methyl propionic acid (isobutyric acid), 2-methyl butyric acid and 3-methyl butyric acid (isovaleric acid).
Jiří ČULÍK +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Roles of short-chain fatty acids in kidney diseases
Chinese Medical Journal, 2019 . Objective:. In kidney diseases, uncontrolled blood pressure, inflammation, oxidative stress, imbalanced immunity response, and metabolic dysfunction were associated with the progressive deterioration of renal function.
Ling-Zhi Li +4 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Grasas y Aceites, 2004 The effect of seasonal and geographical influences on the fatty acid compositions of cow's milk fat from Asturias (northern Spain ) was studied. The majority of the fatty acids analysed presented differences (p < 0.05) due to the seasonal factor, only ...
Leocadio Alonso +2 more
doaj +1 more source