(Tinjauan Pustaka) Efek Perbedaan Sumber Dan Struktur Kimia Asam Lemak Jenuh Terhadap Kesehatan [PDF]
, 2010 . For decades, all saturated fatty acids have always been judged as the only cause of cardiovascular disease without considering the difference of their sources and the length of their carbon chains.
Tuminah, S. (Sulistyowati)
core
Acute oral sodium propionate supplementation raises resting energy expenditure and lipid oxidation in fasted humans [PDF]
, 2018 Short chain fatty acids (SCFAs), produced from fermentation of dietary fibre by the gut microbiota, have been suggested to modulate energy metabolism. Previous work using rodent models have demonstrated that oral supplementation of the SCFA propionate ...
Baldwin +19 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Acetate suppresses myocardial contraction via the short-chain fatty acid receptor GPR43
Frontiers in Physiology, 2022 The heart has high energy requirements, with an estimated 40%–60% of myocardial ATP production derived from the oxidation of fatty acids under physiological conditions.
Xuan Jiang +10 more
doaj +1 more source
Effect of starter cultures on various classes of fatty acids in Sudanese fermented camel milk (Camelus dromedaries) Gariss [PDF]
, 2015 The objective of this research was to study the variation of classes of fatty acids in gariss (fermented camel milk) prepared under controlled conditions (starter cultures and time of fermentation).
Ahmed, Adam Ismail +4 more
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Bioscience of Microbiota, Food and Health, 2020 In recent years, short-chain fatty acids (SCFAs) have been reported to play an important role in maintaining human health. Fecal SCFA concentrations correlate well with colonic SCFA status and gut microbiota composition. However, the associations with the gut microbiota functional pathway, dietary intake, blood SCFAs, and fecal SCFAs remain uncertain ...
Yamamura, Ryodai +8 more
openaire +4 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Binding to medium and long chain fatty acyls is a common property of HEAT and ARM repeat modules. [PDF]
, 2019 Covalent post-translational modification (PTM) of proteins with acyl groups of various carbon chain-lengths regulates diverse biological processes ranging from chromatin dynamics to subcellular localization.
Chua, Katrin F +7 more
core +1 more source
The therapeutic potential of allosteric ligands for free fatty acid sensitive GPCRs [PDF]
, 2013 G protein coupled receptors (GPCRs) are the most historically successful therapeutic targets. Despite this success there are many important aspects of GPCR pharmacology and function that have yet to be exploited to their full therapeutic potential.
Hudson, Brian D. +2 more
core +1 more source
Short Chain Fatty Acids and Colon Cancer [PDF]
The Journal of Nutrition, 2002 The development of intestinal cancer involves complex genetic and epigenetic alterations in the intestinal mucosa. The principal signaling pathway responsible for the initiation of tumor formation, the APC-beta-catenin-TCF4 pathway, regulates both cell proliferation and colonic cell differentiation, but many other intrinsic and extrinsic signals also ...
Leonard H. Augenlicht +6 more
openaire +1 more source