Results 61 to 70 of about 237,743 (266)

King post truss as a motif for internal structure of (meta)material with controlled elastic properties [PDF]

, 2017
One of the most interesting challenges in the modern theory of materials consists in the determination of those microstructures which produce, at the macro-level, a class of metamaterials whose elastic range is many orders of magnitude wider than the one
Dell'Isola, Francesco, Giorgio, Ivan, Misra, Anil, Turco, Emilio   +3 more
core   +4 more sources

Controllability of protein-protein interaction phosphorylation-based networks: Participation of the hub 14-3-3 protein family [PDF]

, 2016
Posttranslational regulation of protein function is an ubiquitous mechanism in eukaryotic cells. Here, we analyzed biological properties of nodes and edges of a human protein-protein interaction phosphorylation-based network, especially of those nodes ...
Bustos, Diego Martin, Flores, Gabriel, Uhart, Marina   +2 more
core   +1 more source

A dynamic view of domain-motif interactions. [PDF]

PLoS Computational Biology, 2012
Many protein-protein interactions are mediated by domain-motif interaction, where a domain in one protein binds a short linear motif in its interacting partner.
Eyal Akiva, Gilgi Friedlander, Zohar Itzhaki, Hanah Margalit   +3 more
doaj   +1 more source

Structure and Dynamics in the ATG8 Family From Experimental to Computational Techniques

Frontiers in Cell and Developmental Biology, 2020
Autophagy is a conserved and essential intracellular mechanism for the removal of damaged components. Since autophagy deregulation is linked to different kinds of pathologies, it is fundamental to gain knowledge on the fine molecular and structural ...
Valentina Sora, Mukesh Kumar, Emiliano Maiani, Matteo Lambrughi, Matteo Tiberti, Elena Papaleo, Elena Papaleo   +6 more
doaj   +1 more source

Cell signaling in Ehrlichia infection and cancer: Parallels in pathogenesis

Frontiers in Cellular and Infection Microbiology
Ehrlichia chaffeensis (E. chaffeensis) has recently emerged as an intracellular bacterial pathogen with sophisticated survival mechanisms that include repurposing evolutionarily conserved eukaryotic cell signaling pathways for immune evasion.
Regina N. Solomon, Nicholas A. Pittner, Jaclyn R. McCoy, Paityn A. Warwick, Jere W. McBride, Jere W. McBride, Jere W. McBride, Jere W. McBride, Jere W. McBride   +8 more
doaj   +1 more source

Mutation of CD2AP and SH3KBP1 binding motif in alphavirus nsP3 hypervariable domain results in attenuated virus [PDF]

, 2018
Infection by Chikungunya virus (CHIKV) of the Old World alphaviruses (family Togaviridae) in humans can cause arthritis and arthralgia. The virus encodes four non-structural proteins (nsP) (nsP1, nsp2, nsP3 and nsP4) that act as subunits of the virus ...
Aquilimeba, Muriel, Kasvandik, Sergo, Lulla, Aleksei, Lulla, Valeria, McInerney, Gerald M., Merits, Andres, Morro, Ainhoa Moliner, Mutso, Margit, Saul, Sirle, Smedberg, Cecilia, Tarve, Liisi, Teppor, Mona, Thaa, Bastian, Varjak, Margus   +13 more
core   +3 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Computational Investigation of Structural Interfaces of Protein Complexes with Short Linear Motifs [PDF]

Journal of Proteome Research, 2020
AbstractProtein complexes with short linear motifs (SLiMs) are known to play important regulatory functions in eukaryotes. In this investigation, I have studied the structures deposited in PDB with SLiMs. The structures Were grouped into three broad categories of protein-protein, protein-peptide and the rest as others.
openaire   +2 more sources

Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins

Biomolecules, 2021
Motifs within proteins help us categorize their functions. Intrinsically disordered proteins (IDPs) are rich in short linear motifs, conferring them many different roles.
Estella A. Newcombe, Catarina B. Fernandes, Jeppe E. Lundsgaard, Inna Brakti, Kresten Lindorff-Larsen, Annette E. Langkilde, Karen Skriver, Birthe B. Kragelund   +7 more
doaj   +1 more source

Complete and incomplete spin transitions in 1D chain iron(II) compounds. [PDF]

, 2011
The synthesis and characterisation of two new octahedral iron(II) SCO coordination polymers [FeL1(bimm)] (1) and [FeL2(bppa)](MeOH)0.5 (2) (L1 = [3,30]-[1,2- phenylenebis-(iminomethylidyne)bis(4-phenyl-,4-butanedionato)(2-)-N,N0,O2,O20], L2 = [E,E ...
Altomare, Bauer, Bauer, Birgit Weber, Brooker, Dirtu, Farrugia, Galet, Gallois, Garcia, Garcia, Genre, Goodwin, Guionneau, Gütlich, Halcrow, Heyn, Jäger, Kahn, Kepert, Kitchen, Koudriavtsev, Koudriavtsev, Koudriavtsev, König, Létard, Macrae, Matouzenko, Matouzenko, Money, Murray, Murray, Müller, Nakano, Neville, Pfaffeneder, Real, Real, Real, Sato, Sebastian Thallmair, Spiering, Toni M. Pfaffeneder, van Koningsbruggen, Weber, Weber, Weber, Weber, Weber, Weber, Weber, Weber, Weber, Weber, Weber, Weber, Weber, Wolf, Wolfgang Bauer   +58 more
core   +2 more sources