Peripheral glia and neurons jointly regulate activity-induced synaptic remodeling at the Drosophila neuromuscular junction [PDF]
eLifeIn the nervous system, reliable communication depends on the ability of neurons to adaptively remodel their synaptic structure and function in response to changes in neuronal activity.
Yen-Ching Chang +4 more
doaj +2 more sources
Cloning of SHV-2, OHIO-1, and OXA-6 beta-lactamases and cloning and sequencing of SHV-1 beta-lactamase [PDF]
Antimicrobial Agents and Chemotherapy, 1990 Molecular cloning of DNA fragments permitted the isolation of structural genes coding for SHV-1, SHV-2, OHIO-1, and OXA-6 beta-lactamases. DNA probes were constructed for SHV-1, and under conditions of high stringency, hybridization was observed only between SHV-1 and SHV-2. Oligonucleotide typing with a 15-mer SHV-1 probe was capable of discriminating
J, Mercier, R C, Levesque
exaly +3 more sources
Comparative genomic insights into multidrug resistance in classical and hypervirulent K. pneumoniae clinical isolates [PDF]
Scientific ReportsKlebsiella pneumoniae is a highly adaptable opportunistic pathogen responsible for various infections, particularly in immunocompromised individuals. The recent genetic evolution of K.
Azra +13 more
doaj +2 more sources
High burden and genetic diversity of β-lactamase-producing Escherichia coli and Klebsiella pneumoniae causing community-acquired urinary tract infections in Southeastern Gabon. [PDF]
PLoS ONEBackgroundThe increasing prevalence of β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in community-acquired urinary tract infections (CA-UTIs) represents a growing public health challenge in low-resource settings.
Yann Mouanga-Ndzime +10 more
doaj +2 more sources
Microorganisms, 2021 Resistance of bacteria to 3rd generation cephalosporins mediated by beta-lactamases (ESBL, pAmpC) is a public health concern. In this study, 1517 phenotypically cephalosporin-resistant E. coli were screened for the presence of blaSHV genes.
Alexandra Irrgang +4 more
doaj +1 more source
Nucleotide sequence of SHV-2 beta-lactamase gene [PDF]
Antimicrobial Agents and Chemotherapy, 1990 The nucleotide sequence of plasmid-mediated beta-lactamase SHV-2 from Salmonella typhimurium (SHV-2pHT1) was determined. The gene was very similar to chromosomally encoded beta-lactamase LEN-1 of Klebsiella pneumoniae. Compared with the sequence of the Escherichia coli SHV-2 enzyme (SHV-2E.coli) obtained by protein sequencing, the deduced amino acid ...
Garbarg-Chenon, A. +3 more
openaire +3 more sources
Nucleotide sequence and phylogeny of SHV-2 beta-lactamase [PDF]
Antimicrobial Agents and Chemotherapy, 1990 We determined the nucleotide sequence of the blaSHV-2(pBP60-1) gene from Klebsiella ozaenae which confers resistance to broad-spectrum cephalosporins. The structural gene encodes a polypeptide product of 286 amino acids, and the estimated molecular weight of the mature protein is 28,900.
A, Huletsky, F, Couture, R C, Levesque
openaire +2 more sources
The Subjective Visual Vertical and the Subjective Haptic Vertical Access Different Gravity Estimates. [PDF]
PLoS ONE, 2015 The subjective visual vertical (SVV) and the subjective haptic vertical (SHV) both claim to probe the underlying perception of gravity. However, when the body is roll tilted these two measures evoke different patterns of errors with SVV generally ...
Lindsey E Fraser +2 more
doaj +1 more source
Single amino acid substitution between SHV‐1 β‐lactamase and cefotaxime‐hydrolyzing SHV‐2 enzyme [PDF]
FEBS Letters, 1988 SHV‐2 β‐lactamase was purified from an overproducing variant of a clinical isolate of Escherichia coli resistant to cefotaxime. Pure protein was digested by trypsin and Lys‐C endoproteinase. Proteolytic peptides, isolated by reverse‐phase HPLC, were submitted to manual Edman degradation and aligned by homology with the sequence of SHV‐1 β‐lactamase.
Barthélémy, Michel +3 more
openaire +2 more sources
Inhibition of Klebsiella β-Lactamases (SHV-1 and KPC-2) by Avibactam: A Structural Study. [PDF]
PLoS ONE, 2015 β-Lactamase inhibition is an important clinical strategy in overcoming β-lactamase-mediated resistance to β-lactam antibiotics in Gram negative bacteria.
Nikhil P Krishnan +4 more
doaj +1 more source