Results 31 to 40 of about 863,961 (270)
Sialic Acids: An Important Family of Carbohydrates Overlooked in Environmental Biofilms
Applied Sciences, 2020 Sialic acids in the structural matrix of biofilms developing in engineered water systems constitute a potential target in the battle against biofouling.
Ingrid S.M. Pinel +5 more
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Sialic acid utilization by Cronobacter sakazakii [PDF]
, 2013 Background: The Cronobacter genus is composed of seven species, and can cause infections in all age groups. Of particular concern is C. sakazakii, as this species is strongly associated with severe and often fatal cases of necrotizing enterocolitis and ...
Forsythe, S +7 more
core +1 more source
Sialic acids and viruses [PDF]
, 2021 Let us study viruses and the role of sialic acids in their first step of reproduction, the attachment to cells. We begin our study with the help of the "Earth's virology course", created by Vincent Racaniello, with David Tuller and Gertrud U. Rey.
Sparavigna, Amelia Carolina +1 more
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Free and bound forms of sialic acid in blood plasma of patients with chronic lymphocytic leukemia
Regulatory Mechanisms in Biosystems, 2015 The level of free and bound forms of sialic acids (SА) was investigated in chronic lymphocytic leukemia (CLL) and at different stages of receiving chemotherapy.
O. V. Netronina
doaj +1 more source
mBio, 2021 All cells in vertebrates are coated with a dense array of glycans often capped with sugars called sialic acids. Sialic acids have many functions, including serving as a signal for recognition of “self” cells by the immune system, thereby guiding an ...
Sudeshna Saha +15 more
doaj +1 more source
Sialic acids: An Avenue to Target Cancer Progression, Metastasis, and Resistance to Therapy
Forum of Clinical Oncology, 2022 Sialic acids are alpha-keto acids with nine carbons that are commonly present in the terminal sugars of glycans on glycoproteins and glycolipids on the cell surface.
Goni Mallikarjun +3 more
doaj +1 more source
Human Neuraminidases Have Reduced Activity Towards Modified Sialic Acids on Glycoproteins [PDF]
, 2020 This work investigated the substrate specificity of hNEU enzymes for a glycoprotein substrate (bovine submaxillary mucin) containing 9-O-acetylated and Neu5Gc residues.
Carmanah D., Hunter +2 more
core +2 more sources
Distinct Roles for Sialoside and Protein Receptors in Coronavirus Infection
mBio, 2020 Coronaviruses (CoVs) are common human and animal pathogens that can transmit zoonotically and cause severe respiratory disease syndromes. CoV infection requires spike proteins, which bind viruses to host cell receptors and catalyze virus-cell membrane ...
Enya Qing +3 more
doaj +1 more source
Sialic Acid Mimetics to Target the Sialic Acid–Siglec Axis
Trends in Biochemical Sciences, 2016 Sialic acid sugars are vital regulators of the immune system through binding to immunosuppressive sialic acid-binding immunoglobulin-like lectin (Siglec) receptors on immune cells. Aberrant sialic acid-Siglec interactions are associated with an increasing number of pathologies including infection, autoimmunity, and cancer.
Büll, C. +3 more
openaire +3 more sources
Multivalent sialic acid binding proteins as novel therapeutics for influenza and parainfluenza infection [PDF]
, 2014 In nature, proteins with weak binding affinity often use a multivalency approach to enhance protein affinity via an avidity effect. Interested in this multivalency approach, we have isolated a carbohydrate binding module (CBM) that recognises sialic ...
Alias, Nadiawati
core +2 more sources