α2,3-Linked Sialic Acids Are the Potential Attachment Receptor for Shaan Virus Infection in MARC-145 Cells [PDF]
Shaan virus (ShaV), a novel species of the genus Jeilongvirus, family Paramyxoviridae, was isolated from an insectivore bat (Miniopterus schreibersii) in Korea in 2016.
Seong Sik Jang +5 more
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Sialic Acids in Health and Disease
Vertebrate cell surfaces exhibit intricate arrangements of glycosaminoglycan polymers, which are primarily linked to lipids and proteins. Numerous soluble secreted proteins are also decorated with either individual sugar molecules or their polymers.
Gerardo N. Guerrero-Flores +5 more
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Genome-wide CRISPR screen reveals key role of sialic acids in PEDV and porcine coronavirus infections [PDF]
Porcine epidemic diarrhea virus (PEDV) is a globally distributed alphacoronavirus with economic importance that can cause severe watery diarrhea and even death in piglets.
Guanghao Guo +12 more
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Sialic acids, sialoconjugates and enzymes of their metabolism in fungi
Sialic acids (Sia) represent a set of derivatives of nine-carbon sugar neuraminic acid that occupy a terminal position in oligosaccharide chains located on the surface of cells. They are very important for several physiological and pathological processes,
Rumyana Eneva +2 more
exaly +2 more sources
Characterization of sialate-O-acetylesterases in the gut commensal bacterium Bacteroides thetaiotamicron [PDF]
The sialic acids are a family of acid sugars that are widely distributed in mammal cells and are found typically linked to the distal end of glycan chains in mammalian glycoproteins, including the mucin proteins found on mucosal surfaces. The most common
Nadat, Fatima
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Sialic acids on B cells are crucial for their survival and provide protection against apoptosis [PDF]
Lars Nitschke +2 more
exaly +2 more sources
Sialometabolism in Brain Health and Alzheimer’s Disease
Sialic acids refer to a unique family of acidic sugars with a 9-carbon backbone that are mostly found as terminal residues in glycan structures of glycoconjugates including both glycoproteins and glycolipids.
Punam Rawal, Liqin Zhao, Liqin Zhao
doaj +1 more source
Early postnatal development encounters milk as a key environmental variable and yet the sole nutrient source. One evolutionary conserved constituent of milk is sialic acid, which is generally displayed on glycoconjugates and free glycans. During early postnatal development, high sialic acid need was proposed to be unmet by the endogenous sialic acid ...
Norbert, Sprenger, Peter I, Duncan
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Determination of sialic acids in the nervous system of silkworm (Bombyx mori L.): Effects of aging and development [PDF]
Sialic acids mainly occur as components on cell surface glycoproteins and glycolipids. They play a major role in the chemical and biological diversity of glycoconjugates. Although sialic acids exhibit great structural variability in vertebrates,
Soya Seçkin +3 more
doaj +1 more source
Synthesis of Sialic Acids and Sialic Acid Derivatives [PDF]
Sialic acids as such, sialic acid derivatives, analogues, glycosides and sialooligosaccharides have been subject of many synthetic investigations. These studies were aimed at a further exploration of the properties of sialic acids, the preparation of substrates and inhibitors for sialidases, sialyltransferases or for sialic acid converting enzymes, and
Vliegenthart, J.F.G., Kamerling, J.P.
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