Results 31 to 40 of about 20,212 (212)

Vaccination targeting a surface sialidase of P. acnes: implication for new treatment of acne vulgaris. [PDF]

PLoS ONE, 2008
Acne vulgaris afflicts more than fifty million people in the United State and the severity of this disorder is associated with the immune response to Propionibacterium acnes (P. acnes). Systemic therapies for acne target P.
Teruaki Nakatsuji, Yu-Tsueng Liu, Cheng-Po Huang, Christos C Zouboulis, Richard L Gallo, Chun-Ming Huang   +5 more
doaj   +1 more source

Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation [PDF]

, 2015
The authors acknowledge the support of the Biotechnology and Biological Sciences Research Council (BBSRC), this research was partly funded by the BBSRC Institute Strategic Programme for The Gut Health and Food Safety (BB/J004529/1) and by the BB/L008602 ...
Vos, W.M., de, Hardy-Goddard, Jemma, Crost, Emmanuelle H., de Vos, Willem M., Gall, G., Le, Taylor, Garry L., Walshaw, J., Tailford, L.E., Crost, E.H., Taylor, G.L., Juge, N., Owen, C.D., Tailford, Louise E., Owen, C. David, Le Gall, G., Le Gall, Gwenaelle, Hardy-Goddard, J., Juge, Nathalie, Walshaw, John, de Vos, W.M.   +19 more
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Evaluation of inhibitor activity of bacterial sialidase from Clostridium perfringens against Newcastle disease virus in the cell culture model using chicken embryo fibroblast

Journal of Advanced Veterinary and Animal Research, 2022
Objective: The Newcastle disease virus (NDV) is an infectious disease that causes very high eco¬nomic losses due to decreased livestock production and poultry deaths.
Ryan Septa Kurnia, Rahajeng Setiawaty, Ketut Karuni Nyanakumari Natih, Christian Marco Hadi Nugroho, Otto Sahat Martua Silaen, Silvia Tri Widyaningtyas, Simson Tarigan, Fera Ibrahim, Pratiwi Pudjilestari Sudarmono   +8 more
doaj   +1 more source

Retrospective survey for sialidase activity in Mycoplasma pneumoniae isolates from cases of community-acquired pneumonia

BMC Research Notes, 2011
Background Sialidase is a well-known virulence factor of other respiratory pathogens, but was only recently documented to occur in some species of Mycoplasma.
Brown Daniel R, May Meghan
doaj   +1 more source

Structural characterization of the carbohydrate-binding module of NanA sialidase, a pneumococcal virulence factor [PDF]

, 2015
This research was supported by the University of St Andrews and grants provided by the Medical Research Council.Background: Streptococcus pneumoniae Neuraminidase A (NanA) is a multi-domain protein anchored to the bacterial surface.
Helen Connaris, Yang, Lei, Garry L. Taylor, Taylor, Garry Lindsay, Lei Yang, Potter, Jane Alexandra, Connaris, Helen, Jane A. Potter   +7 more
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Sialidase Inhibitors with Different Mechanisms [PDF]

, 2022
[Image: see text] Sialidases, or neuraminidases, are enzymes that catalyze the hydrolysis of sialic acid (Sia)-containing molecules, mostly removal of the terminal Sia (desialylation).
Joseph M. Keil, Majdi A. Aljohani, Rafn, Garrett R., Sahebjam-Atabaki, Reza, Garrett R. Rafn, Reza Sahebjam-Atabaki, Keil, Joseph M., Sun, Xue-Long, Isaac M. Turan, Xue-Long Sun, Turan, Isaac M., Aljohani, Majdi A., Keil, Joseph M.   +12 more
core   +1 more source

Hypomorphic sialidase expression decreases serum cholesterol by downregulation of VLDL production in mice

Journal of Lipid Research, 2012
Lipoprotein metabolism is an important contributing factor in the development and progression of atherosclerosis. Plasma lipoproteins and their receptors are heavily glycosylated and sialylated, and levels of sialic acids modulate their biological ...
Abraham Yang, Gabriel Gyulay, Mark Mitchell, Elizabeth White, Bernardo L. Trigatti, Suleiman A. Igdoura   +5 more
doaj   +1 more source

Transmembrane Peptides as a New Strategy to Inhibit Neuraminidase-1 Activation

Frontiers in Cell and Developmental Biology, 2020
Sialidases, or neuraminidases, are involved in several human disorders such as neurodegenerative, infectious and cardiovascular diseases, and cancers.
Camille Albrecht, Camille Albrecht, Andrey S. Kuznetsov, Andrey S. Kuznetsov, Andrey S. Kuznetsov, Aline Appert-Collin, Aline Appert-Collin, Zineb Dhaideh, Zineb Dhaideh, Maïté Callewaert, Maïté Callewaert, Yaroslav V. Bershatsky, Yaroslav V. Bershatsky, Anatoly S. Urban, Anatoly S. Urban, Eduard V. Bocharov, Eduard V. Bocharov, Dominique Bagnard, Dominique Bagnard, Stéphanie Baud, Stéphanie Baud, Sébastien Blaise, Sébastien Blaise, Béatrice Romier-Crouzet, Béatrice Romier-Crouzet, Roman G. Efremov, Roman G. Efremov, Roman G. Efremov, Manuel Dauchez, Manuel Dauchez, Manuel Dauchez, Laurent Duca, Laurent Duca, Marc Gueroult, Marc Gueroult, Pascal Maurice, Pascal Maurice, Amar Bennasroune, Amar Bennasroune   +38 more
doaj   +1 more source

3-Exomethylene Sialic Acid Disaccharides as Substrate-Type Mechanism-Based Sialidase Inhibitors [PDF]

, 2022
We designed α(2,3)- and α(2,6)-sialylgalactose analogues bearing an exomethylene unit at C3 of sialic acid (3-exoSia) as a novel type of mechanism-based inhibitors of sialidases.
Taeko , Miyagi, Keiya , Uezono, Risa , Maeda, Masaki , Morita, Kana , Oonuma, Ryo , Fukazawa, Mikiko, Sodeoka, Marie, Kato, Hiroyuki , Koshino, Go, Hirai   +9 more
core   +2 more sources

Glycohistochemical study of the toadfish Halobatrachus didactylus (Scheider, 1801) stomach

Scientia Marina, 2009
Toadfish Halobatrachus didactylus gastric mucosa was studied using conventional and lectin histochemistry. Conventional histochemistry revealed neutral glycoconjugates predominating over acidic ones in the apical zone of both surface epithelial cells and
Salvatore Desantis, Franca Acone, Sara Zizza, Michele Deflorio, Josè Luis Palazón Fernández, Carmen Sarasquete, Gregorio De Metrio   +6 more
doaj   +1 more source