Results 21 to 30 of about 26,062 (215)

Two different sialidases, KDN-sialidase and regular sialidase in the starfish Asterina pectinifera [PDF]

Biochemical Journal, 1996
We have found the coexistence of two different sialidases in the entrails of the starfish Asterina pectinifera: a regular sialidase (RS), which cleaves sialic acid from sialoglycoconjugates, and a KDN-sialidase (KS) which releases the sialic acid analogue KDN (2-keto-3-deoxy-D-glycero-d-galacto-nononic acid) from KDN-containing glycoconjugates that are
J A, Yuziuk, H, Nakagawa, A, Hasegawa, M, Kiso, S C, Li, Y T, Li   +5 more
openaire   +2 more sources

Characterization of NanR Regulation of Sialidase Production, Sporulation and Enterotoxin Production by Clostridium perfringens Type F Strains Carrying a Chromosomal Enterotoxin Gene

Toxins, 2022
Clostridium perfringens type F food poisoning (FP) strains produce C. perfringens enterotoxin (CPE) to cause a common bacterial food-borne illness in the United States. During FP, CPE is synthesized in the intestines when C.
Jihong Li, Eric Mi, Arhat Pradhan, Bruce A. McClane   +3 more
doaj   +1 more source

Cutaneous Sialidase

Journal of Investigative Dermatology, 1982
A fluorometric microassay is described for sialidase using the natural substrate sialyllactose. This technique has been used to characterize and quantify cutaneous sialidase. The enzyme was found exclusively in the particulate fraction of skin homogenates.
Mier, P.D., van Rennes, Helga, van Erp, P.E.J., Roelfzema, H.   +3 more
openaire   +2 more sources

Role of Sialidase in Long-Term Potentiation at Mossy Fiber-CA3 Synapses and Hippocampus-Dependent Spatial Memory. [PDF]

PLoS ONE, 2016
Sialic acid bound to glycans in glycolipids and glycoproteins is essential for synaptic plasticity and memory. Sialidase (EC 3.2.1.18), which has 4 isozymes including Neu1, Neu2, Neu3 and Neu4, regulates the sialylation level of glycans by removing ...
Akira Minami, Masakazu Saito, Shou Mamada, Daisuke Ieno, Tomoya Hikita, Tadanobu Takahashi, Tadamune Otsubo, Kiyoshi Ikeda, Takashi Suzuki   +8 more
doaj   +1 more source

Sialidase Activity in the Cervicovaginal Fluid Is Associated With Changes in Bacterial Components of Lactobacillus-Deprived Microbiota

Frontiers in Cellular and Infection Microbiology, 2022
IntroductionSialidase activity in the cervicovaginal fluid (CVF) is associated with microscopic findings of bacterial vaginosis (BV). Sequencing of bacterial 16S rRNA gene in vaginal samples has revealed that the majority of microscopic BV cases fit into
Carolina Sanitá Tafner Ferreira, Camila Marconi, Camila Marconi, Cristina M. G. L. Parada, Jacques Ravel, Marcia Guimaraes da Silva   +5 more
doaj   +1 more source

Sialidase Activity in Human Blood Serum Has a Distinct Seasonal Pattern: A Pilot Study

Biology, 2020
Desialylation—loss of terminal sialic acid residues from glycoconjugates catalyzed by sialidases—is involved in many human diseases and is considered a key molecular event of atherosclerosis onset.
Victor Y. Glanz, Dmitry A. Kashirskikh, Andrey V. Grechko, Shaw-Fang Yet, Igor A. Sobenin, Alexander N. Orekhov   +5 more
doaj   +1 more source

Genetic and functional characterization of the NanA sialidase from Clostridium chauvoei

Veterinary Research, 2011
Clostridium chauvoei is the causative agent of blackleg, a wide spread serious infection of cattle and sheep with high mortality. In this study we have analyzed the sialidase activity of the NanA protein of C. chauvoei and cloned the sialidase gene nanA.
Vilei Edy M, Johansson Anders, Schlatter Yvonne, Redhead Keith, Frey Joachim   +4 more
doaj   +1 more source

Increase of intestinal bacterial sialidase activity exacerbates acute colitis in mice

Frontiers in Molecular Biosciences, 2022
The availability of endogenous and dietary carbohydrates in the gastrointestinal tract influences the composition of the gut microbiota. Carbohydrate foraging requires the action of bacterially-encoded glycoside hydrolases, which release mono- and ...
Tobias Hasler, Leticia Tavares-Gomes, Sereina Gut, Meghna Swayambhu, Mario Gysi, Martin Hausmann, Natasha Arora, Thierry Hennet   +7 more
doaj   +1 more source

Antibody against Microbial Neuraminidases Recognizes Human Sialidase 3 (NEU3): the Neuraminidase/Sialidase Superfamily Revisited

mBio, 2017
Neuraminidases (NAs) are critical virulence factors for several microbial pathogens. With a highly conserved catalytic domain, a microbial NA “superfamily” has been proposed.
Chiguang Feng, Jihong Li, Greg Snyder, Wei Huang, Simeon E. Goldblum, Wilbur H. Chen, Lai-Xi Wang, Bruce A. McClane, Alan S. Cross   +8 more
doaj   +1 more source

Evaluation of inhibitor activity of bacterial sialidase from Clostridium perfringens against Newcastle disease virus in the cell culture model using chicken embryo fibroblast

Journal of Advanced Veterinary and Animal Research, 2022
Objective: The Newcastle disease virus (NDV) is an infectious disease that causes very high eco¬nomic losses due to decreased livestock production and poultry deaths.
Ryan Septa Kurnia, Rahajeng Setiawaty, Ketut Karuni Nyanakumari Natih, Christian Marco Hadi Nugroho, Otto Sahat Martua Silaen, Silvia Tri Widyaningtyas, Simson Tarigan, Fera Ibrahim, Pratiwi Pudjilestari Sudarmono   +8 more
doaj   +1 more source